keratinization disorders (DBCOND0021324)

Identifiers

Synonyms

Hyperkeratoses / Ichthyoses / Keratinization / Diffuse palmoplantar keratoderma of Thost-Unna (disorder) / Hyperkeratosis (morphologic abnormality) / Hyperkeratosis / Ichthyosis (disorder) / Skin change ichthyosiform / Ichthyosis / Keratinization (function)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Acitretin	An oral retinoid used in the treatment of severe psoriasis.	Retinoic acid receptor alphatarget Retinoic acid receptor RXR-betatarget Retinoic acid receptor gammatarget Retinoic acid receptor betatarget Retinoic acid receptor RXR-gammatarget Retinoic acid receptor RXR-alphatarget Albumincarrier Retinol-binding protein 1target Retinoic acid receptor RXRtarget Signal transducer and activator of transcription 3target
Salicylic acid	An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.	Albumincarrier Prostaglandin G/H synthase 1target Prostaglandin G/H synthase 2target Aldo-keto reductase family 1 member C1target Solute carrier family 22 member 6transporter Solute carrier family 22 member 10transporter Organic anion transporter 3transporter Solute carrier family 22 member 11transporter Solute carrier organic anion transporter family member 2B1transporter Monocarboxylate transporter 1transporter Solute carrier family 22 member 7transporter Cytochrome P450 2C9enzyme Carbonic anhydrase 6target Carbonic anhydrase 12target Carbonic anhydrase 2target Carbonic anhydrase 4target Carbonic anhydrase 1target

Clinical Trials

Not Available