Salicylic acid



Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.

Brand Names
Actikerall, Bensal, Bioelements Active Astringent, Cantharone Plus, Clearasil, Diprosalic, Keralyt, Salex, Saliject, Salinocaine, Salvax, Ultrasal, Virasal
Generic Name
Salicylic acid
DrugBank Accession Number

A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.

Small Molecule
Approved, Investigational, Vet approved
Average: 138.1207
Monoisotopic: 138.031694058
Chemical Formula
  • 2-Carboxyphenol
  • 2-Hydroxybenzoic acid
  • ácido salicílico
  • Acidum salicylicum
  • O-carboxyphenol
  • O-hydroxybenzoic acid
  • Salicylic acid
External IDs
  • FEMA NO. 3985
  • K-557
  • NSC-180



Key additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to treatAcneCombination Product in combination with: Benzoic acid (DB03793), Octasulfur (DB09353)••••••••••••••••••••
Treatment ofAcne••• •••
Used in combination to treatActinic keratosisCombination Product in combination with: Fluorouracil (DB00544)••••••••••••
Used in combination to treatAlopecia areata (aa)Combination Product in combination with: Flumethasone (DB00663)••••••••••••••••••••
Used in combination to treatAtopic dermatitis (ad)Combination Product in combination with: Flumethasone (DB00663)••••••••••••••••••••
Associated Therapies
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Salicylic acid treats acne by causing skin cells to slough off more readily, preventing pores from clogging up. This effect on skin cells also makes salicylic acid an active ingredient in several shampoos meant to treat dandruff. Use of straight salicylic solution may cause hyperpigmentation on unpretreated skin for those with darker skin types (Fitzpatrick phototypes IV, V, VI), as well as with the lack of use of a broad spectrum sunblock. Subsalicylate in combination with bismuth form the popular stomach relief aid known commonly as Pepto-Bismol. When combined the two key ingredients help control diarrhea, nausea, heartburn, and even gas. It is also very mildly anti-biotic.

Mechanism of action

Salicylic acid directly irreversibly inhibits COX-1 and COX-2 to decrease conversion of arachidonic acid to precursors of prostaglandins and thromboxanes. Salicylate's use in rheumatic diseases is due to it's analgesic and anti-inflammatory activity. Salicylic acid is a key ingredient in many skin-care products for the treatment of acne, psoriasis, calluses, corns, keratosis pilaris, and warts. Salicylic acid allows cells of the epidermis to more readily slough off. Because of its effect on skin cells, salicylic acid is used in several shampoos used to treat dandruff. Salicylic acid is also used as an active ingredient in gels which remove verrucas (plantar warts). Salicylic acid competitively inhibits oxidation of uridine-5-diphosphoglucose (UDPG) with nicotinamide adenosine dinucleotide (NAD) and noncompetitively with UDPG. It also competitively inhibits the transferring of the glucuronyl group of uridine-5-phosphoglucuronic acid (UDPGA) to a phenolic acceptor. Inhibition of mucopoly saccharide synthesis is likely responsible for the slowing of wound healing with salicylates.

AProstaglandin G/H synthase 1
AProstaglandin G/H synthase 2
UAldo-keto reductase family 1 member C1

Not Available

Volume of distribution

The volume of distribution is about 170 mL/kg of body weight.3

Protein binding

Salicylic acid is about 90% plasma protein bound.3


Salicylic acid is extensively metabolized.3

Route of elimination

About 10% is excreted unchanged in the urine.3


Not Available


Not Available

Adverse Effects
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Oral rat LD50: 891 mg/kg. Inhalation rat LC50: > 900 mg/m3/1hr. Irritation: skin rabbit: 500 mg/24H mild. Eye rabbit: 100 mg severe. Investigated a mutagen and reproductive effector.

Salicylic Acid Action PathwayDrug action
Pharmacogenomic Effects/ADRs
Not Available


Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
AbacavirSalicylic acid may decrease the excretion rate of Abacavir which could result in a higher serum level.
AbataceptThe metabolism of Salicylic acid can be increased when combined with Abatacept.
AbciximabThe risk or severity of bleeding and hemorrhage can be increased when Salicylic acid is combined with Abciximab.
AbrocitinibThe metabolism of Abrocitinib can be decreased when combined with Salicylic acid.
AcamprosateThe excretion of Acamprosate can be decreased when combined with Salicylic acid.
Food Interactions
No interactions found.


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Product Ingredients
IngredientUNIICASInChI Key
Choline magnesium trisalicylateDJJ95FJP1H64425-90-7FQCQGOZEWWPOKI-UHFFFAOYSA-K
Diethylamine salicylate5V7PT38BJU4419-92-5JGMKRAUEFASZKH-UHFFFAOYSA-N
Potassium salicylateK91YT16P5M578-36-9FRMWBRPWYBNAFB-UHFFFAOYSA-M
Active Moieties
Product Images
International/Other Brands
Dr. Scholl's Callus Removers / Dr. Scholl's Corn Removers / Dr. Scholl's Wart Remover Kit / Duofil Wart Remover / Duoplant / Ionil Plus shampoo / Salonil / Salsonin / Stridex
Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
28.5% Salicylic AcidSolution285 mg/1mLTopicalElorac, Inc.2018-04-30Not applicableUS flag
AcNesic Acne TreatmentGel0.5 g/100gTopicalBlaine Labs Inc.2021-04-06Not applicableUS flag
AliclenShampoo60 mg/1mLTopicalPrasco, Laboratories2011-02-022014-01-31US flag
Bensal HPOintment30 mg/1gTopicalSmg Pharmaceuticals, Llc1998-10-01Not applicableUS flag
Bioelements Active AstringentLiquid0.5 mL/100mLTopicalBioelements2009-01-01Not applicableUS flag
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
111MedCo 2% Salicylic Acid Cleansing BarSoap20 mg/1gTopical111MedCo LLC2022-07-01Not applicableUS flag
24 Hour Pimple PunisherCream; Kit2 g/100mLTopicalKATE SOMERVILLE SKINCARE, LLC2014-06-222018-11-18US flag
28 Remedy Acne Pore Deep CleanserGel0.6 g/120mLTopicalNoTS Co.,Ltd2016-01-022018-12-01US flag
28 Remedy Balancing Toner 10mLCream0.001 mg/10mLTopicalNoTS Co Ltd2015-09-012018-12-01US flag
3 in 1 CleanserLiquid1 mg/1mgTopicalSGII, INC.2018-06-292020-09-30US flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
2% Salicylic Acid FACIAL CLEANSERSalicylic acid (20 mg/236mL) + Azelaic acid (10 mg/236mL) + Glycerin (50 mg/236mL) + Kaolin (20 mg/236mL) + Zinc pidolate (10 mg/236mL)LiquidTopicalVolans Epic LLC2023-04-06Not applicableUS flag
24 Alopecia ReliefshampooSalicylic acid (0.25 g/100mL) + Menthol (0.3 g/100mL) + Panthenol (0.2 g/100mL)ShampooTopicalDERMA CENTRIC INC2020-08-08Not applicableUS flag
3 Part Acne Treatment Kit Ceela NaturaalsSalicylic acid (20 mg/1mL) + Salicylic acid (20 mg/1mL)KitTopicalCeela Naturals, Llc2017-10-09Not applicableUS flag
3 Part Acne Treatment Kit Ceela NaturaalsSalicylic acid (20 mg/1mL) + Salicylic acid (20 mg/1mL)KitTopicalCeela Naturals, Llc2017-10-09Not applicableUS flag
30 day Acne Treatment KitSalicylic acid (0.5 g/100mL) + Benzoyl peroxide (5 g/100mL)KitTopicalCOSMETIC ENTERPRISES LTD2023-08-23Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
24 Alopecia ReliefshampooSalicylic acid (0.25 g/100mL) + Menthol (0.3 g/100mL) + Panthenol (0.2 g/100mL)ShampooTopicalDERMA CENTRIC INC2020-08-08Not applicableUS flag
28 Remedy Balancing Toner 10mLSalicylic acid (0.001 mg/10mL)CreamTopicalNoTS Co Ltd2015-09-012018-12-01US flag
28.5% Salicylic AcidSalicylic acid (285 mg/1mL)SolutionTopicalElorac, Inc.2018-04-30Not applicableUS flag
AC Out Spot stOp SerumSalicylic acid (0.1 mg/100mL)LiquidTopicalThe Doctors Cosmetics Co., Ltd2012-09-27Not applicableUS flag
Ac7Salicylic acid (0.000001 g/10mL)GelTopicalMicell Korea Co.,ltd2017-03-20Not applicableUS flag


ATC Codes
D01AE12 — Salicylic acidG04BX17 — Sodium salicylate and methenamineN02BA04 — Sodium salicylateN02BA12 — Potassium salicylateS01BC08 — Salicylic acid
Drug Categories
Chemical TaxonomyProvided by Classyfire
This compound belongs to the class of organic compounds known as salicylic acids. These are ortho-hydroxylated benzoic acids.
Organic compounds
Super Class
Benzene and substituted derivatives
Sub Class
Benzoic acids and derivatives
Direct Parent
Salicylic acids
Alternative Parents
Benzoic acids / Benzoyl derivatives / 1-hydroxy-4-unsubstituted benzenoids / 1-hydroxy-2-unsubstituted benzenoids / Vinylogous acids / Monocarboxylic acids and derivatives / Carboxylic acids / Organooxygen compounds / Organic oxides / Hydrocarbon derivatives
1-hydroxy-2-unsubstituted benzenoid / 1-hydroxy-4-unsubstituted benzenoid / Aromatic homomonocyclic compound / Benzoic acid / Benzoyl / Carboxylic acid / Carboxylic acid derivative / Hydrocarbon derivative / Monocarboxylic acid or derivatives / Organic oxide
Molecular Framework
Aromatic homomonocyclic compounds
External Descriptors
monohydroxybenzoic acid (CHEBI:16914)
Affected organisms
  • Humans and other mammals

Chemical Identifiers

CAS number
InChI Key
2-hydroxybenzoic acid


Synthesis Reference

Howard Jones, Robert W. Houser, "Process for preparing 4-(2,4-difluorophenyl)-salicyclic acid." U.S. Patent US4225730, issued August, 1972.

General References
  1. Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971 Jun 23;231(25):232-5. [Article]
  2. Flower R, Gryglewski R, Herbaczynska-Cedro K, Vane JR: Effects of anti-inflammatory drugs on prostaglandin biosynthesis. Nat New Biol. 1972 Jul 26;238(82):104-6. [Article]
  3. FDA Approved Drug Products: HELIDAC Therapy (bismuth subsalicylate, metronidazole, and tetracycline) [Link]
Human Metabolome Database
KEGG Compound
PubChem Compound
PubChem Substance
Therapeutic Targets Database
Guide to Pharmacology
GtP Drug Page
PDBe Ligand
PDB Entries
1fiq / 1fo4 / 1jgs / 1m6e / 1pth / 1wyg / 1y7i / 2e1q / 2fn1 / 2i2z
show 60 more

Clinical Trials

Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package
PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
Not AvailableRecruitingBasic ScienceBullous Pemphigoid (BP)1somestatusstop reasonjust information to hide
4Active Not RecruitingBasic ScienceChronic Obstructive Pulmonary Disease (COPD)1somestatusstop reasonjust information to hide
4Active Not RecruitingTreatmentAcute Hemorrhagic Stroke1somestatusstop reasonjust information to hide
4Active Not RecruitingTreatmentCongenital Hypothyroidism1somestatusstop reasonjust information to hide
4Active Not RecruitingTreatmentDimethicone Adverse Reaction / Dimethicone Allergy / Ivermectin / Pediculus Capitis Infestation / Permethrin Adverse Reaction / Permethrin Allergy / School Age Children1somestatusstop reasonjust information to hide


Not Available
  • 7 Oaks Pharmaceutical Corp.
  • Aeropak (Uk)
  • Auriga Pharmaceuticals LLC
  • Avidas Pharmaceuticals
  • Breckenridge Pharmaceuticals
  • Collegium Pharmaceutical Inc.
  • Contract Pharm
  • Coria Laboratories
  • Direct Dispensing Inc.
  • DPT Laboratories Ltd.
  • Elorac Inc.
  • EMS Acquisition Corp.
  • Groupe Parima Inc.
  • Harmony Laboratories Inc.
  • Hi Tech Pharmacal Co. Inc.
  • JSJ Pharmaceuticals Inc.
  • Kaiser Foundation Hospital
  • Kamins Dermatologics Inc.
  • Major Pharmaceuticals
  • Medtech Labs
  • Murfreesboro Pharmaceutical Nursing Supply
  • Nucare Pharmaceuticals Inc.
  • Onset Therapeutics LLC
  • PD-Rx Pharmaceuticals Inc.
  • Perrigo Co.
  • Pharmedix
  • Physicians Total Care Inc.
  • Pliva Inc.
  • Prasco Labs
  • PruGen Inc. Pharmaceuticals
  • Qualitest
  • River's Edge Pharmaceuticals
  • Seton Pharmaceuticals LLC
  • Sheffield Laboratories Div Faria Limited LLC
  • Sonar Products Inc.
  • Southwood Pharmaceuticals
  • Span Packaging Services LLC
  • Stiefel Labs
  • Summers Labs
  • Valeant Ltd.
Dosage Forms
Cream; kitTopical2 g/100mL
GelTopical0.6 g/120mL
CreamTopical0.001 mg/10mL
LiquidTopical1 g/100g
LiquidTopical1 mg/1mg
SwabTopical0.024 g/1
LiquidTopical0.1 mg/100mL
GelTopical0.000001 g/10mL
SolutionTopical22.5 mg/15mL
Injection, solutionIntramuscular1000 mg
Injection, solutionIntramuscular; Intravenous1 g/5ml
CreamTopical14 g/100g
LiquidTopical1.2 g/240mL
DiscTopical20 g/1000g
GelTopical7 mg/354mg
LiquidTopical3.61 g/3.61g
LotionTopical1.18 g/1.18g
GelTopical2 mg/100mg
LiquidTopical0.02 g/1
CreamTopical2000 mg/100mL
SoapTopical3.4 g/168g
SprayTopical0.5 g/100mL
LiquidTopical29.2 mg/1
PatchPercutaneous5 mg/1000mg
PatchTransdermal5 mg/1000mg
LotionTopical1 g/50mL
CreamTopical18 mg/1g
LiquidTopical0.75 mg/150mL
GelTopical0.5 %
CreamTopical2 mg/100mg
GelTopical20 g/100g
LotionTopical18.6 mg/1mL
LotionTopical0.295 g/59mL
GelTopical21 mg/1mL
GelTopical0.01 g/1g
CreamTopical0.5 mg/1mL
CreamTopical0.15 g/30g
SolutionTopical0.2 g/40g
LotionTopical1.0 mL/100mL
LiquidTopical.5 g/100mL
LiquidTopical.5 g/.5mL
CreamTopical0.5 g/100mL
GelTopical5 mg/1g
CreamTopical2 g/1mL
PatchTopical2 g/100mL
LiquidTopical2 g/200mL
LiquidTopical2 g/100mL
SwabTopical.5 g/100mL
SwabTopical5 mg/1000mg
SwabTopical5 mg/1mL
SprayTopical2.84 g/142g
SolutionTopical20 mg/1
GelTopical2 mg/100mL
ClothTopical5 mg/1
GelTopical0.6 g/30mL
LotionTopical1.0 mg/1mL
LiquidTopical1.93 mL/96.5mL
CreamTopical1.5 %
CreamCutaneous0.3 g/15mL
PatchTopical2 mg/100mg
Cream; gel; kitTopical
SoapTopical2 g/100g
PlasterTopical.4 1/1001
PlasterTopical40 1/1
Aerosol, foamTopical1.5 g/100g
ClothTopical2 g/1
CreamTopical2 g/100g
ClothTopical2 g/101
ClothTopical2 g/301
EmulsionTopical2 g/100g
LotionTopical1 g/100g
LotionTopical2.0 g/100g
LotionTopical2.0 mL/100mL
CreamTopical2.0 g/100g
OintmentTopical0.1 g/g
CreamTopical10 %
SprayTopical10 %
ShampooTopical60 mg/1mL
Kit; tabletOral
GelTopical.5 %
PowderTopical0.6 mg/1mL
LiquidTopical0.01 g/1mL
LiquidTopical2 mg/2mL
LiquidTopical0.5 mg/1mL
EmulsionTopical1 mg/1mL
PowderTopical0.002 g/1g
PowderTopical0.6 %
StripTopical1.4 %
Liquid; swabTopical.5 %
LiquidTopical.5 %
LiquidTopical1.0 g/200mL
LiquidTopical0.25 g/50mL
LiquidTopical0.018 mg/1mg
LotionTopical250 g/5g
ShampooTopical200 g/6g
CreamTopical50 g/1g
GelOral; Topical2 g
GelTopical2 g
LotionTopical2 g
CreamTopical0.08 g/20mL
CreamTopical5 mg/1g
GelTopical15 mg/1g
ShampooTopical2.5 g/100mL
GelTopical2 mL/100mL
ShampooTopical0.2 g/100mL
LiquidTopical0.1 g/100mL
GelTopical15 uL/1mL
SwabTopical10 uL/1mL
JellyTopical1 %
LotionTopical3 g/100mL
RinseTopical2.0 g/397g
ShampooTopical2.0 g/414g
GelTopical0.1 g/1g
LotionTopical2 g/100g
DiscTopical20 mg/1
StickTopical2 g/100g
LotionTopical1 mg/100mL
LotionTopical10 mg/1g
LotionTopical5 % w/v
SprayTopical2 g/100mL
ShampooTopical30 mg/100mL
ShampooTopical3 mg/100mL
PasteTopical0.0401 g
CreamTopical2.6 g/130mL
SwabTopical0.0046 g/1
LotionTopical0.75 mg/150mL
LotionTopical11 mg/1mL
OilTopical18 mg/1mL
ClothTopical20 mg/1mL
ClothTopical176 mg/1
LotionTopical8 mg/1mL
ClothTopical0.5 g/100g
CreamTopical.5 mL/100mL
LotionTopical2 mL/100mL
ShampooTopical2 g/414g
RinseTopical2 g/397g
PatchTopical0.5 g/100g
SolutionTopical1.5 g/100mL
SolutionTopical15 mg/1g
SoapTopical0.50 %
SoapTopical0.5 g/100g
ClothTopical6 mg/1
SoapTopical.5 %
SoapTopical5 mg/1g
LiquidTopical2 mg/200mL
LotionTopical0.7 %
StickTopical2 %
LotionTopical1.5 %
LiquidTopical1.5 %
SwabTopical40 %
EmulsionTopical20 mg/1mL
EmulsionTopical10 mg/1g
PowderTopical30 mg/6g
LiquidTopical5 mg/100mL
SolutionTopical0.05 g/100mL
GelTopical1.3 g/91g
LiquidTopical2.1 g/100mL
SolutionTopical.5 g/100mL
LotionTopical0.064 % w/v
OintmentTopical0.05 % w/w
LotionTopical1 %
ShampooTopical0.24 mg/355mL
SprayTopical2 mg/355mL
OintmentTopical2.8 g/140g
GelTopical1.8 %
LiquidTopical0.5 mL/100mL
GelTopical1.27 g/127g
GelTopical2.5 g/127g
LiquidTopical4.3 g/200mL
LiquidTopical4.56 g/236mL
SuspensionTopical0.5 g/100mL
GelTopical2 g/200mL
GelTopical1.3 g/127g
LiquidTopical2.8 g/141g
LiquidTopical2.54 g/127g
SolutionTopical1.8 g/100mL
ShampooTopical0.6 g/300mL
SprayTopical0.24 g/120mL
Kit; liquid; shampooTopical
ShampooTopical0.4 g/200mL
GelTopical19.4 mg/1g
RinseTopical0.2 mg/100mg
LotionTopical0.587 g/118mL
LotionTopical1500 mg/29000mg
LiquidTopical15 mg/1mL
LotionTopical2 g/120mL
ClothTopical0.8 mg/80g
LotionTopical1.5 g/15mL
LotionTopical0.6 g/200mL
LotionTopical0.6 g/100mL
LotionTopical2 g/40mL
ClothTopical10 mg/1
StripTopical0.03 mg/1
LotionTopical0.75 g/100mL
SprayTopical1.95 g/100mL
SprayTopical1.8 g/100mL
SprayTopical20 mg/1g
GelTopical25 mg/1mL
GelTopical1.25 g/250mL
LiquidTopical10 mg/1mL
GelTopical0.4 g/20g
PatchTransdermal0.5 1/1
SolutionTopical20 g
SolutionOral; Topical12.6 g
OintmentTopical5 g/1g
PatchTopical0.19 mg/1
PatchTopical11.9 mg/21
ShampooTopical0.3 g/100mL
LiquidTopical0.2 g/100mL
CreamTopical7.0753 g/237mL
PlasterTopical40 %
OintmentTopical10 mg/1g
LotionTopical2 % w/v
CreamTopical20.6 mg/1mL
LiquidOral500 mg/5mL
PowderTopical1 g/100g
CreamTopical0.156 g/8.9mL
CreamTopical0.28 g/14g
LiquidTopical0.623 g/130mL
LiquidTopical0.691 g/133mL
PasteTopical5 mg/1g
Kit; liquid; lotionTopical
LiquidTopical0.07 g/30mL
Kit; liquidTopical0.5 g/100mL
LiquidTopical2 mg/100mg
SwabTopical2 g/100mL
SprayTopical2 g/118mL
LiquidTopical14.4 mg/1mL
LotionTopical28.8 mg/1mL
LiquidTopical28.8 mg/1mL
GelTopical2 g/151mL
GelTopical30 mg/1mL
CreamTopical50 mg/1mL
LiquidTopical50 mg/1mL
GelTopical1.0 g/100g
LotionTopical0.5 g/100mL
GelTopical0.3 g/15mL
CreamTopical0.6 g/60mL
LiquidTopical2.4 g/240mL
ClothTopical283.5 mg/56.7g
LotionTopical0.0053 g/100mL
LotionTopical0.0091 g/100mL
ClothTopical0.5 mg/90mL
GelTopical0.5 mg/118mL
LotionTopical2 mg/15mL
LotionTopical0.5 mg/50mL
Kit; oilTopical0.3 g/50mL
LiquidTopical2.00 %
GelTopical1 g/100mL
GelTopical2 %
Gel; kit; liquidTopical
SolutionTopical2 g/100g
SalveTopical20 mg/1mL
LiquidTopical3.57 mg/1mL
ClothTopical10 mg/1mL
Aerosol, foamTopical20 mg/1mL
GelTopical2 g/100g
LotionTopical0.01 g/1g
LotionTopical.01 g/1g
CreamTopical.02 g/1g
LotionTopical7 mg/1mL
Cloth; cream; kit; lotionTopical
SolutionTopical0.03 g/1
SolutionTopical0.01 g/1
SolutionTopical0.015 g/1
LotionTopical1 g/100mL
SolutionTopical1 g/100mL
LiquidTopical2 %
SolutionTopical1.25 g
Kit; lotionTopical
ClothTopical0.02 g/1
Cloth; kit; lotionTopical
ClothTopical0.03 g/1
LotionTopical1.9 g/100mL
CreamTopical1.9 g/100mL
SolutionTopical0.02 g/1
SolutionTopical2 g/100mL
LotionTopical2 g/100mL
GelTopical10 g/0.2g
CreamTopical50 g/0.5g
GelTopical0.5 g/100g
LiquidTopical0.5 mg/100mL
GelTopical18.4 mg/1mL
CreamTopical10 mg/1g
LotionTopical0.5 g/59g
LiquidTopical5 mL/250mL
PasteTopical5 mg/1mL
LotionTopical0.6 mL/30mL
LiquidTopical10 mg/1g
GelTopical0.3 mL/15mL
CreamTopical1.5 mL/75mL
GelTopical0.022 mL/1.1mL
CreamTopical1 mL/50mL
GelTopical0.375 mL/75mL
GelTopical5 mg/1mL
GelTopical0.30 mL/15mL
LiquidTopical20 mg/1mL
StickTopical2 g/2mL
SprayTopical2 %
LiquidTopical1 %
CreamTopical1 %
GelTopical1 %
PowderTopical0.5 g/100g
LiquidTopical2.5 mg/500mL
OintmentTopical2 % w/w
LiquidTopical1.5 g/100mL
SolutionTopical100 mg
GelTopical0.17 g/7g
GelTopical170 mg/1g
GelTopical17 %
LiquidTopical20 %
LiquidTopical0.17 g/9g
LiquidTopical30 %
Gel; kitTopical170 mg/1g
CreamTopical2 1/100g
EmulsionTopical0.24 mg/29.6mg
EmulsionTopical1.89 mg/237mg
Powder, for solutionOral
PlasterTopical40 mg/1
OintmentTopical15 %
PlasterTopical50 %w/w
CreamTopical1 g/100g
GelTopical0.3 mg/30mL
StickTopical0.025 g/2.5g
GelTopical0.1425 g/30mL
Gel; kitTopical10 mg/1mL
CreamTopical1 mg/100mL
LiquidTopical2 mg/30mg
CreamTopical1.5 g/50mL
LotionTopical1.5 mg/100mg
StickTopical2 mg/100mg
PatchTopical40 mg/1
GelTopical20 mg/1mL
SoapTopical20 mg/1mL
LiquidTopical5 mg/1mL
StickTopical40 g/100g
SoapTopical20 mg/1g
ShampooTopical30 mg/1mL
LiquidTopical3 g/100mL
LiquidTopical20.5 mg/1mL
Kit; liquid; sprayTopical
ShampooTopical0.018 g/1mL
SwabTopical0.02 mL/1
CreamTopical5.05 mg/1mL
SolutionTopical2.4 mL/120mL
CreamTopical1 mg/1mg
LotionTopical0.015 g/1g
LiquidTopical17.64 mg/1mL
LiquidTopical2 g/1mL
PasteTopical20 mg/1g
ShampooTopical0.03 g/1mL
LotionTopical.5 %
GelTopical18 mg/1g
LotionTopical2 mg/1mL
GelTopical2 mg/1g
LiquidTopical20 mg/1g
GelTopical3 %
GelTopical3.54 mL/118mL
LiquidTopical1.15 mg/230mL
LiquidTopical1.8 mg/180mL
CreamTopical0.5 mg/50mL
LotionTopical0.5 g/1
LotionTopical2 g/1
LiquidTopical0.5 g/100g
LiquidTopical50.5 mg/2.5mL
LotionTopical30 mg/1.5mL
ShampooTopical3.0 %
ShampooTopical0.035 g/1g
SoapTopical4.8 g/240g
SolutionTopical20 mg/1mL
Aerosol, sprayTopical2 g/100g
LiquidTopical0.25 g/100mL
LiquidTopical25 g/100mL
ShampooTopical1.25 g/500mL
TabletOral325 mg
TabletOral325 mg / tab
TabletOral500 mg / tab
Solution / dropsBuccal
OintmentTopical20 mg/1mL
Cream; kitTopical
CreamTopical0.75 g/150mL
GelTopical1 g/50mL
CreamTopical0.01 g/15mL
SprayTopical0.14 g/140mL
GelTopical0.1 g/100mL
LiquidTopical0.3 g/10mL
ShampooTopical0.25 mg/100mL
LiquidTopical0.17 g/70mL
LiquidTopical12.64 %
SolutionTopical150 mg/1mL
DiscTopical4 mg/1
SolutionTopical1.7 mg/1mL
DiscTopical0.4 g/1
DiscTopical4.00 mg/1
LiquidTopical0.48 mL/100mL
LiquidTopical0.48 g/100mL
LiquidCutaneous0.5 mg/100mg
CreamCutaneous0.5 mg/100mg
LiquidTopical1 mg/100mL
CreamTopical0.00001 g/100mL
SolutionTopical16.7 %
GelTopical11 %
LiquidTopical150.28 mg/1mL
GelTopical27 g
SolutionTopical260 mg/1mL
PatchTopical3.0 mg/30mL
PatchTopical0.002 1/1
LotionTopical6 %w/w
CreamTopical2.0 g/100mL
PowderTopical1.0 g/100g
PasteTopical2.0 g/100g
LiquidTopical1.0 g/100g
PasteTopical1.0 g/100g
OintmentTopical1 mg/g
StickTopical2 g/100mL
CreamTopical0.5 g/100g
LotionTopical1.0 mg/1g
CreamTopical2.8 g/141g
GelTopical0.006 g/1g
GelTopical20 g/1000mL
Liquid, extended releaseTopical2 mg/100mL
PasteTopical20 mg/1mL
SwabTopical20 mg/1
ShampooTopical20 mg/1mL
SoapTopical2000 mg/100mL
LiquidTopical170 mL/1mL
LiquidTopical40 mg/1
CreamTopical1 g/100mL
GelTopical50 mg/1mL
Tablet, film coatedOral
GelTopical0.5 g/100mL
LiquidTopical17 g/100mL
PatchTopical0.012 mg/3mg
ClothTopical2 g/100mL
DiscTopical2 g/100mL
GelTopical5 % w/w
SoapTopical2 %
CreamTopical2 %
LiquidTopical2.16 mg/120mL
LiquidTopical158.4 mg/1mL
SolutionTopical13.4 g
Cream, augmentedTopical5 mg/1mL
LotionTopical7.2 % w/v
LotionTopical5 mg/100mL
ShampooTopical2 mg/100mL
OilTopical10 mg/1mL
Kit; liquidTopical20 mg/1mL
LiquidTopical2 g/100g
SolutionTopical30 mg/1mL
SolutionTopical15 mg/1mL
SprayTopical20 mg/1mL
SolutionTopical4.8 g/240mL
Aerosol, foamTopical.5 mL/100mL
LotionTopical10 mg/1
LiquidTopical4 mL/200mL
GelTopical2000 mg/1g
Gel; kitTopical
GelTopical21.2 mg/100mL
LotionTopical3 g/100g
SuspensionTopical0.56 g/29mL
LiquidTopical3 g/100g
Aerosol, foamTopical0.7 mg/1mL
CreamTopical1. g/100g
Lotion / shampooTopical20 mg/1mL
CreamTopical1 g/120g
RinseTopical17.575 mg/1mL
RinseTopical18.13 mg/1mL
GelTopical2.0 %
SolutionTopical1.0 mg/200mL
SoapTopical0.4 g/100g
LiquidTopical3 mg/118mL
Lotion / shampooTopical18.5 mg/1mL
PatchTopical; Transdermal0.0401 g
ShampooTopical0.1 1/300mL
LiquidTopical0.02 kg/1kg
OilTopical1 mg/100mL
LiquidTopical1.6 g/320mL
LiquidTopical3 %
CreamCutaneous2 mg/100mL
Kit; liquidTopical10 mg/1mL
LotionTopical1.184 mL/59.2mL
GelTopical17 g/100g
GelTopical0.55 g/100mL
Kit; liquid; oil; patchTopical
LiquidTopical0.003 g/1mL
LiquidTopical0.0001 g/1mL
LotionTopical2.15 g/110mL
LiquidTopical1.2 g/120mL
SoapTopical1.35 g/135g
GelTopical20 g/1000g
CreamTopical3 %
LiquidTopical1.5 g/100g
GelTopical2 mg/2mL
CreamTopical0.5 mg/0.5mL
LiquidTopical20 g/1L
GelTopical0.02 mL/1mL
LotionTopical0.02 mL/1mL
ShampooTopical0.5 g/100mL
CreamTopical0.5 %
JellyTopical.5 %
CreamTopical.5 %
CreamTopical0.0015 g/15g
ShampooTopical28 mg/1g
RinseTopical15 mg/1mL
CreamTopical100 mg/1g
GelTopical6 g/100g
Gel; kit; shampooTopical
ShampooTopical5 g/100mL
ShampooTopical6 g/92.6mL
GelTopical3 g/100g
GelTopical5 g/100g
GelTopical6 %
ShampooTopical10 mg/1mL
ShampooTopical19 mg/1mL
LotionTopical15 mg/1mL
LotionTopical12 mg/1mL
CreamTopical0.15105 g/15mL
PatchTopical0.0125 mg/0.6216mg
LiquidTopical5.88 mg/1mL
CreamTopical0.025 mg/5mL
CreamTopical2.0 mCi/100mL
SolutionTopical5 mg/1mL
PatchTopical5 g/100g
LiquidTopical0.5 g/100mL
LiquidTopical0.6 g/100mL
OintmentTopical53.3 g
PatchTopical2 g/1
PatchTopical0.005 g/1
PatchTopical5 g/1
Cream; suspensionTopical0.5 %
GelTopical10 mg/1mL
ShampooTopical1 g/100mL
SprayTopical4.72 mL/118mL
ClothTopical.6 mL/60mL
GelTopical.75 mL/50mL
GelTopical0.425 mL/25mL
PasteTopical0.75 mL/150mL
StickTopical36 mg/1.8g
ShampooTopical0.1 mg/100mL
LiquidTopical0.25 mg/100mL
OintmentTopical53.33 g
LiquidTopical.75 %
ShampooTopical29 mg/1mL
Aerosol, foamTopical5 mg/1g
PlasterTopical0.4 g/1g
PlasterTopical0.40 g/1g
LiquidTopical17 mg/100mg
SwabTopical.02 mL/1
GelTopical19.8 mg/1g
DiscTopical40 %
SoapTopical2 g/100mL
PatchTopical0.4 g/181
ShampooTopical1.8 g/100mL
PlasterTopical40 g/100g
PatchTopical0.056 mg/1
PlasterTopical2.068 mg/1
PlasterTopical3.175 mg/1
PlasterTopical5.51 mg/1
ShampooTopical2 g / 100 g
LiquidTopical7 mg/100mL
SolutionTopical14.8 g
ShampooTopical0.03 g/1g
PatchTopical0.5 mg/100mg
OintmentTopical10 %
PatchTopical5 mg/1g
CreamTopical2.016 g/112g
LiquidTopical0.5 mg/100mg
LotionTopical30 mg/1mL
SolutionTopical0.15 mg/30mL
ClothTopical1 g/100g
ShampooTopical0.2 1/300g
LiquidTopical10 mg/100mL
LiquidTopical150 mg/1mL
PlasterTopical4 mg/1
OintmentTopical40 %
LotionTopical0.501 g/100mL
LiquidTopical0.3 g/120mL
SolutionTopical0.10 g/25mL
LotionTopical1.5 g/100mL
LiquidTopical0.06 g/1mL
ShampooTopical0.06 g/1mL
EmulsionTopical1 g/100g
LiquidTopical0.75 g/100g
LiquidTopical1 g/1001
CreamTopical30 mL/100mL
LotionTopical10 mg/1mL
LiquidTopical1.0 mL/100mL
LotionTopical0.5 mg/1mL
ShampooTopical0.01 g/100mL
CreamTopical20 mg/1g
GelTopical0.7 g/100mL
GelTopical0.02 g/1g
SwabTopical0.5 g/100mL
SwabTopical2 mL/100mL
GelTopical1.0 mg/1g
Aerosol, foamTopical20 mg/1g
StripTopical20 mg/1
Cream; kit; lotionTopical
LiquidTopical1.8 %
ClothTopical20 mg/1
LotionTopical5 mg/1mL
SuspensionTopical20 mg/1mL
GelTopical20 mg/1g
ShampooTopical25 mg/1mL
LotionTopical2.0 %
CreamTopical5.5 mg/1g
LiquidTopical5 mg/1g
GelTopical1.5 %
CreamTopical1.0 %
PowderTopical5 mg/1g
SprayTopical5 mg/1mL
CreamTopical20 mg/1mL
OintmentTopical2 g/100g
GelTopical1 mL/100mL
GelTopical3 mg/15mL
LiquidTopical1 g/50g
GelTopical0.1 g/20mL
SoapTopical0.01 g/1g
ClothTopical0.02 g/1g
ClothTopical.05 mg/100mg
LotionTopical5 g/1000mL
GelTopical5 g/1000mL
GelTopical5.5 g/1000mL
Solution, gel forming / dropsTopical20 mg/1mL
ShampooTopical9 mg/500g
LiquidTopical170 mg / g
ClothTopical20.5 mg/1mL
LiquidTopical2.5 g/125g
LotionTopical20.6 mg/1mL
LotionTopical20 mg/1mL
LiquidTopical18 mg/1mL
GelTopical3 g/150g
GelTopical4 mg/177mg
CreamTopical.5 mL/50mL
GelTopical1.15 mL/115mL
GelTopical.06 mL/15mL
LiquidTopical19.6 mg/1mL
Solution / dropsOphthalmic
PatchTopical0.4 g/1g
SoapTopical0.27 g/55g
SoapTopical0.50 g/100g
SoapTopical0.40 g/80g
SolutionTopical10 mg/1mL
SwabTopical5 mg/1
SolutionTopical5 mg/1g
LotionTopical5 mg/1g
SuspensionTopical0.5 %
LotionTopical2 %
SwabTopical2 %
SwabTopical.5 %
PatchTopical5 mg/1
SprayTopical2 g/100mg
CreamTopical30 mg/1g
PlasterTopical0.4 g/1
PasteTopical0.57 g
KitTopical5 mg/1g
Kit; patchTopical5 mg/1g
Kit; lotion; solutionTopical
SprayTopical20.6 mg/1mL
PatchTopical0.359 mg/1
PatchTopical0.5 mg/1
PatchTopical0.1575 mg/1
PatchTopical4 mg/1
PlasterTopical17.67 mg/44.18mg
StripTopical4.42 mg/1
PlasterTopical11.04 mg/1
CreamTopical1 mg/20mg
RinseTopical2 g/100g
LotionTopical2.0 g/100mL
SolutionTopical2.0 g/100mL
LiquidTopical0.025 g/1
LiquidTopical2.0 mL/100mL
CreamTopical15 mg/1mL
ConcentrateTopical2 g/100mL
GelTopical2.0 g/100mL
LiquidTopical0.05 g/100mL
SolutionTopical0.013 mg/2.5mL
LiquidTopical.7 %
CreamTopical0.02 g/1mL
CreamTopical100 mg / g
PatchTopical40 mg/100mg
OintmentCutaneous0.40 g
GelTopical0.008776 g/1mL
OintmentTopical5 % w/w
LotionTopical1.8 mg/180mg
SoapTopical2 mg/100g
SprayTopical2 mg/100mL
LotionTopical0.5 mg/100mL
Lotion / shampooTopical2 g/100mL
CreamTopical0.02 g/1000mL
LotionTopical2 mg/100mL
GelTopical5 mg/1000mL
SolutionTopical5 mg/1000mL
CreamTopical1.5 g/100g
LiquidTopical2 mg/100mL
CreamTopical0.01 g/1g
GelTopical0.2 g/100mL
Lotion / shampooTopical0.02 g/1000mL
GelTopical0.5 mg/100mL
LiquidTopical0.5 %
LotionTopical0.5 %
SwabTopical0.5 %
LiquidTopical0.02 g/45mL
GelTopical1.77 g/59mL
Gel; kitTopical1.77 g/59mL
Lotion / shampooTopical1.33 g/74mL
CreamTopical2.26 g/113g
CreamTopical1.1 g/56.7g
SoapTopical3 g/100g
ShampooTopical3 g/100g
CreamTopical2.5 g/100g
CreamTopical3 g/100g
GelTopical3 g/100mL
CreamTopical3 g/100mL
LiquidTopical1.8 g/100mL
EmulsionTopical2 g/100mL
GelTopical0.0001 g/120g
GelTopical0.012 g/120g
PatchTopical0.6 g/100mm
CreamTopical0.5 ug/1mL
SolutionIntragingival; Oropharyngeal
LiquidTopical0.003 g/ml
SolutionBuccal; Oral
CreamTopical17 g/100g
LiquidTopical2 mg/1mL
EmulsionTopical15 mg/1mL
LiquidTopical1.5 g/1
CreamTopical59 mg/1g
ShampooTopical2 g/100mL
SwabTopical20 mg/1mL
SprayTopical4.8 mL/240mL
SoapTopical0.6 g/100g
CreamTopical2 mL/100mL
PatchTopical0.04 g/40mL
CreamTopical3 g/150mL
SwabTopical0.005 mg/1mL
SwabTopical0.02 mg/1mL
OilTopical2 mg/100mL
LiquidTopical1 mL/100mL
StickTopical1 %
SoapTopical0.3 g/100g
SwabTopical21 mg/1
LotionTopical0.18 g/30g
LotionTopical0.95 %
ShampooTopical0.25 g/100mL
OintmentTopical40 g
GelCutaneous0.020 g
SoapTopical1.2 g/1.2g
CreamTopical0.5 g/0.5g
GelTopical0.72 g/0.72g
PlasterTopical14.13 mg/1
CreamTopical24 g/400g
LotionTopical24.84 mg/414mL
LotionTopical60 mg/1mL
GelTopical1.2 g/60g
GelTopical10 mg/100mL
LotionTopical1 g/1g
CreamTopical1 g/0.25mL
CreamTopical6 g/100g
GelTopical0.17 g/1g
GelTopical0.21 g/1.25g
GelTopical60 mg/1g
KitTopical60 mg/1mL
KitTopical60 mg/1g
LiquidTopical0.17 mg/9.8g
LiquidTopical0.17 mg/15mL
LiquidTopical0.17 mg/9mL
LiquidTopical0.17 g/9.8mL
LiquidTopical0.17 mg/151mL
LiquidTopical0.17 mg/9.8mL
LiquidTopical0.17 g/9mL
LiquidTopical2.1 g/14.7mL
LiquidTopical260 mg/1mL
LiquidTopical275 mg/1mL
LotionTopical0.5 g/60mL
LotionTopical2.1 g/100g
LotionTopical6 g/100mL
LotionTopical6 mg/100mL
LotionTopical60 mg/1g
OintmentTopical30 mg/1g
PatchTopical40 mg/61
PatchTopical40 mg/141
PatchTopical40 mg/81
PatchTopical40 mg/121
PatchTopical40 mg/181
PatchTopical40 mg/91
PatchTopical40 mg/241
PatchTopical40 mg/41
PatchTopical400 mg/1g
PlasterTopical0.4 g/141
PlasterTopical0.4 g/1411
PlasterTopical0.4 g/181
PlasterTopical40 mg/141
PowderNot applicable1 g/1g
ShampooTopical2 g/100g
ShampooTopical6 mg/100mL
ShampooTopical60 mg/1g
SolutionTopical275 mg/1mL
SolutionTopical285 mg/1mL
CreamTopical2 % w/w
SwabTopical0.5 mg/100mg
StripTopical40 mg/1
TabletTopical2 g/1001
SoapTopical3.5 %
GelTopical.01 mg/1g
LiquidIntravenous570 mg / mL
GelTopical15 mg/1mL
LotionTopical1.66 g/1.66g
GelTopical2 g/2g
CreamTopical60 mg/1g
LotionTopical0.06 g/1mL
Aerosol, foamTopical6 g/100g
LotionTopical20 mg
Aerosol, foamTopical3.88 g/70g
PatchTopical40 g/1001
LiquidTopical3.4 g/20mL
SoapTopical0.54 g/100mL
GelTopical0.54 g/100.00mL
GelTopical2.18 g/100.00mL
SolutionTopical8.85 % w/v
LiquidTopical12 g/100mL
OintmentTopical6 % w/w
ShampooTopical3.0 g/100mL
LiquidTopical30 mg/1g
LiquidTopical0.01 mg/1mg
SolutionTopical2.8 % w/w
LiquidTopical17 %
LiquidTopical1.7 mg/1mL
DiscTopical0.4 g/1g
LiquidTopical1 g/100mL
LiquidTopical1.22 g/490mL
GelTopical0.4 g/200g
GelTopical8 g/100g
PasteTopical1 g/100g
GelTopical1 g/100g
ShampooTopical0.2 mg/100mL
Liquid; shampooTopical
ShampooTopical0.02 g/1mL
LotionTopical6.3 % w/v
GelTopical154 mg/30mL
CreamTopical1.8 %
PatchTopical32 mg/1
PatchTopical25.6 mg/1001
LiquidTopical1.5 mg/100mL
RinseTopical0.50 mL/100mL
LiquidTopical20 g/2mL
LiquidTopical5 g/2mL
CreamTopical1.8 mg/1g
CreamTopical1.8 g/100g
PatchTopical2 g/100g
Cream; kit; liquidTopical
Kit; liquidTopical2 g/100mL
LiquidTopical4 g/100g
LiquidTopical0.2 g/1g
OintmentTopical1.8 g/50g
GelTopical.5 g/100g
ClothTopical2 g/100g
LiquidTopical20 mg/1
SprayTopical9.72 mg/1mL
SolutionTopical17 %
ShampooTopical18 mg/1L
LiquidTopical0.005 g/100mL
LiquidTopical0.01 g/100mL
GelTopical0.001 g/100mL
SolutionTopical170 mg/1g
LiquidTopical2 g/29mL
GelTopical1 g/59mL
SwabTopical3 g/100g
CreamTopical2.0 %
PatchTopical1.24 g/1
LiquidTopical0.009506 g/100mL
CreamTopical0.065 mg/13mL
SolutionTopical10 %
GelTopical10 %
EmulsionTopical0.02 g/1g
EmulsionTopical0.01 g/1g
LotionTopical0.02 g/1g
EmulsionTopical0.01 g/1mL
EmulsionTopical0.02 mL/1mL
EmulsionTopical0.02 g/1mL
EmulsionTopical0.01 mL/1mL
LiquidTopical2.2 %
SoapTopical0.01 mL/1mL
SoapTopical0.02 mL/1mL
SoapTopical0.02 g/1g
GelCutaneous; Topical0.572 mg/50000mg
GelTopical2 g/100mL
LiquidTopical0.1 g/1
OintmentTopical20 mg/1g
OilTopical15 mg/1mL
LotionTopical0.95 % w/v
ShampooTopical2 %
SuspensionTopical2 %
ShampooTopical3 %
GelTopical1.5 g/100mL
SolutionTopical170 mg/1mL
OintmentTopical3 g/100g
StickTopical12.0 g/100g
StickTopical15.0 g/100g
LotionTopical1.0 g/100g
LotionTopical0.02 g/1
LiquidCutaneous10 mg/1mL
GelCutaneous5 mg/1mL
OintmentTopical0.14 g/28g
CreamTopical1 g/50g
ShampooTopical18 mg/1mL
CreamTopical16 mg/1g
ShampooTopical9 g/500g
OintmentTopical5 % w/w
LiquidTopical0.2 g/100g
LiquidTopical.0024 mg/.120mg
PlasterTopical15 %
OintmentExtracorporeal17 mg/100mL
ShampooTopical3 g/100mL
SoapTopical1 g/100g
SwabTopical0.02 g/1
LiquidTopical0.1 mg/1mL
PatchTopical40 mg/100g
SolutionTopical50 mg/1mL
CreamTopical2 g/100mL
CreamTopical11.4 g/100mL
CreamTopical0.005 g/1mL
CreamTopical170 mg/1mL
EmulsionTopical20 mg/1g
TapeTopical4 mg/1
SolutionTopical8 g/100g
PatchTopical0.4 g/100g
LiquidTopical170 mg/1mL
LiquidTopical17 mL/10mL
LiquidTopical2 mL/100mL
DiscTopical17.67 mg/44.18mg
LiquidTopical0.15 g/100mL
SprayTopical15 mg/1mL
LotionTopical20 mg/1g
EmulsionTopical1.2 g/120mL
Lotion / shampooTopical30 mg/1mL
LiquidTopical30 mg/1mL
LiquidTopical1.7 mg/10mL
LiquidTopical12 mg/100mL
PlasterTopical40 mL/1
LiquidTopical0.17 g/1g
SolutionTopical10 g/100mL
LiquidTopical2.51 mL/14.78mL
StickTopical.4 g/1g
LiquidTopical0.02 g/1g
GelTopical4 g/200g
SwabTopical0.5 g/100g
SwabTopical1 g/100g
SwabTopical2 g/100g
SoapTopical0.001 g/0.1g
SoapTopical1 mg/100g
SolutionTopical280 mg/1g
OintmentCutaneous2 % w/w
ShampooTopical10 g/325g
GelTopical5 mg/237mg
GelTopical0.75 mg/150mL
PlasterTopical40 g/1
PlasterTopical; Transdermal40 g/1
PlasterTopical156 mg/1
SoapTopical0.5 g/110g
LiquidTopical5.3 g/265mL
GelTopical1.0 g/100mL
ClothTopical5 mg/1mL
SuspensionTopical10 mg/1g
StickTopical1 g/100g
GelTopical1.0 mg/100mL
StripTopical5 mg/1mL
CreamTopical10 mg/1mL
CreamTopical5 mg/1mL
SolutionTopical2.0 mg/100mL
CreamTopical0.47 g/100mL
CreamTopical0.47 mL/100mL
LiquidTopical0.47 mL/100mL
LiquidTopical0.47 g/100mL
GelTopical0.47 g/100mL
GelTopical0.47 mL/100mL
ClothCutaneous20 mg/1300mg
GelTopical0.06 g/25mL
LiquidTopical0.4 g/100mL
KitTopical20 mg/1mL
StickTopical20 mg/1g
PatchTopical20 mg/1mL
Kit; patchTopical20 mg/1mL
Unit descriptionCostUnit
Keralyt scalp complete kit67.8USD kit
Keralyt 6% Gel 100 gm Tube51.99USD tube
Keralyt 6% Gel 40 gm Tube49.99USD tube
Compound W 17% Liquid 9.3ml Bottle11.99USD bottle
Keralyt 3% Gel 28.4 gm Tube11.35USD tube
Sastid soap4.32USD each
Salicylic acid 6% gel1.14USD g
Salactic film solution0.74USD ml
Compound w pads0.5USD each
Keralyt 6% gel0.5USD g
Freezone corn-callus liquid0.42USD ml
Keralyt 3% gel0.39USD g
Salicylic acid 6% shampoo0.21USD ml
Ionil plus 2% shampoo0.05USD ml
Ionil t plus shampoo0.05USD ml
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Not Available


Experimental Properties
melting point (°C)158 °CPhysProp
boiling point (°C)211 °C at 2.00E+01 mm HgPhysProp
water solubility2240 mg/L (at 25 °C)YALKOWSKY,SH & DANNENFELSER,RM (1992)
logP2.26HANSCH,C ET AL. (1995)
logS-1.82ADME Research, USCD
Caco2 permeability-4.79ADME Research, USCD
Predicted Properties
Water Solubility11.3 mg/mLALOGPS
pKa (Strongest Acidic)2.79Chemaxon
pKa (Strongest Basic)-6.3Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area57.53 Å2Chemaxon
Rotatable Bond Count1Chemaxon
Refractivity35.3 m3·mol-1Chemaxon
Polarizability12.81 Å3Chemaxon
Number of Rings1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Human Intestinal Absorption+0.9756
Blood Brain Barrier+0.6165
Caco-2 permeable+0.8867
P-glycoprotein substrateNon-substrate0.734
P-glycoprotein inhibitor INon-inhibitor0.9815
P-glycoprotein inhibitor IINon-inhibitor0.9937
Renal organic cation transporterNon-inhibitor0.9167
CYP450 2C9 substrateNon-substrate0.7962
CYP450 2D6 substrateNon-substrate0.9233
CYP450 3A4 substrateNon-substrate0.766
CYP450 1A2 substrateNon-inhibitor0.9517
CYP450 2C9 inhibitorNon-inhibitor0.7984
CYP450 2D6 inhibitorNon-inhibitor0.9659
CYP450 2C19 inhibitorNon-inhibitor0.7644
CYP450 3A4 inhibitorNon-inhibitor0.8675
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.8525
Ames testNon AMES toxic0.9829
BiodegradationReady biodegradable0.8086
Rat acute toxicity2.2160 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9631
hERG inhibition (predictor II)Non-inhibitor0.9734
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397)


Mass Spec (NIST)
Download (8.17 KB)
SpectrumSpectrum TypeSplash Key
GC-MS Spectrum - GC-MS (2 TMS)GC-MSsplash10-014i-3890000000-62eae168a9d7ab3ada6f
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSsplash10-0079-8900000000-e8ee46d81fcc1ce3766e
GC-MS Spectrum - EI-BGC-MSsplash10-00du-9700000000-e1e2ee6b61d86c596403
GC-MS Spectrum - GC-MSGC-MSsplash10-014i-3890000000-62eae168a9d7ab3ada6f
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-014i-2960000000-1b6b46cbb2b643b71448
Mass Spectrum (Electron Ionization)MSsplash10-00du-9600000000-6d4a0ff2d48d814b5c54
MS/MS Spectrum - Quattro_QQQ 10V, NegativeLC-MS/MSsplash10-059j-9600000000-54545731fceee84be340
MS/MS Spectrum - Quattro_QQQ 25V, NegativeLC-MS/MSsplash10-00xu-9500000000-2f1c989b672669aaf083
MS/MS Spectrum - Quattro_QQQ 40V, NegativeLC-MS/MSsplash10-0gb9-9000000000-a0049e982e8ecd7ab730
LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, NegativeLC-MS/MSsplash10-000i-0900000000-f1e71df6894bcc8dda74
LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, NegativeLC-MS/MSsplash10-0006-9200000000-f9fd317c182ec7ca90dc
LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, NegativeLC-MS/MSsplash10-0006-9000000000-2b17aea4ee0ddd6321cf
LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, NegativeLC-MS/MSsplash10-0006-9000000000-320b7cd879b61439cf42
LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, NegativeLC-MS/MSsplash10-0006-9000000000-7d1b96d60026076a7ecc
MS/MS Spectrum - ESI-TOF , NegativeLC-MS/MSsplash10-002b-0496100000-97708001d2a6d031beff
MS/MS Spectrum - ESI-TOF 10V, NegativeLC-MS/MSsplash10-002b-0496100000-97708001d2a6d031beff
MS/MS Spectrum - ESI-TOF , NegativeLC-MS/MSsplash10-002b-0496100000-97708001d2a6d031beff
MS/MS Spectrum - ESI-TOF 10V, NegativeLC-MS/MSsplash10-000i-0900000000-f88c693bac9b89416a52
MS/MS Spectrum - DI-ESI-qTof , PositiveLC-MS/MSsplash10-00di-0900000000-2aeace8112266d938c2b
LC-MS/MS Spectrum - LC-ESI-QFT , negativeLC-MS/MSsplash10-0006-9400000000-b0fb5458dfa73429b976
LC-MS/MS Spectrum - LC-ESI-QFT , negativeLC-MS/MSsplash10-0006-9400000000-b0fb5458dfa73429b976
LC-MS/MS Spectrum - LC-ESI-QFT , negativeLC-MS/MSsplash10-0006-9100000000-237ee14e8af5262c0dab
LC-MS/MS Spectrum - LC-ESI-QFT , negativeLC-MS/MSsplash10-0006-9000000000-3ec5d7a9114e37b8af2a
LC-MS/MS Spectrum - LC-ESI-QFT , negativeLC-MS/MSsplash10-0006-9000000000-d8fdab29114453b10280
LC-MS/MS Spectrum - LC-ESI-QFT , negativeLC-MS/MSsplash10-0006-9000000000-4a337e3639c9f42a9000
LC-MS/MS Spectrum - LC-ESI-QFT , negativeLC-MS/MSsplash10-0006-9000000000-2deb0e843e099fdcea99
LC-MS/MS Spectrum - LC-ESI-QFT , negativeLC-MS/MSsplash10-00kf-9000000000-951b374b351c5534628a
LC-MS/MS Spectrum - LC-ESI-QFT , negativeLC-MS/MSsplash10-014l-9000000000-4ea52d5aa4344a40c007
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-000i-0900000000-f1e71df6894bcc8dda74
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-0006-9200000000-65f3f297188dc07b53be
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-0006-9000000000-2b17aea4ee0ddd6321cf
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-0006-9000000000-320b7cd879b61439cf42
LC-MS/MS Spectrum - LC-ESI-QQ , negativeLC-MS/MSsplash10-0006-9000000000-7d1b96d60026076a7ecc
LC-MS/MS Spectrum - LC-ESI-TOF , negativeLC-MS/MSsplash10-000i-0900000000-f88c693bac9b89416a52
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-00di-0900000000-dd7c7e9bb99d16d9e3b3
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-00di-0900000000-2106a18c58cc09ba35d2
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-00di-0900000000-79094eef5dfa59aa3723
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-00di-1900000000-333f3c35ef30a1009fde
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-00di-3900000000-1650d1f6c5415fb2e6c3
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-01b9-9700000000-e00d66b41e77653cb63f
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-014i-9100000000-37a9d14bd1eea4079faa
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-014i-9000000000-38a1383fd22f1277e48e
LC-MS/MS Spectrum - LC-ESI-QFT , positiveLC-MS/MSsplash10-014i-9000000000-af5a2b43adf8dc36435f
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-00di-2900000000-54ec0ff4eb6aca6bd639
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-00xu-9300000000-8719923b080ae4a17ade
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-9000000000-221b5c08a6ad94e05f34
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-9000000000-28c69a70af451a39ae02
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0gb9-9000000000-aaf910fd3a0a6c5f4511
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-02tc-9000000000-53309ffe434005aea194
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-00di-2900000000-54ec0ff4eb6aca6bd639
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-9000000000-221b5c08a6ad94e05f34
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-00xu-9300000000-8719923b080ae4a17ade
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0006-9000000000-28c69a70af451a39ae02
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-0gb9-9000000000-aaf910fd3a0a6c5f4511
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-02tc-9000000000-53309ffe434005aea194
1H NMR Spectrum1D NMRNot Applicable
1H NMR Spectrum1D NMRNot Applicable
13C NMR Spectrum1D NMRNot Applicable
Predicted 1H NMR Spectrum1D NMRNot Applicable
Predicted 13C NMR Spectrum1D NMRNot Applicable
[1H,1H] 2D NMR Spectrum2D NMRNot Applicable
[1H,13C] 2D NMR Spectrum2D NMRNot Applicable
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DeepCCS 1.0 (2019)
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DeepCCS 1.0 (2019)
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DeepCCS 1.0 (2019)
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DeepCCS 1.0 (2019)
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DeepCCS 1.0 (2019)
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DarkChem Lite v0.1.0
DeepCCS 1.0 (2019)


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Pharmacological action
General Function
Prostaglandin-endoperoxide synthase activity
Specific Function
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gas...
Gene Name
Uniprot ID
Uniprot Name
Prostaglandin G/H synthase 1
Molecular Weight
68685.82 Da
  1. Moon C, Ahn M, Jee Y, Heo S, Kim S, Kim H, Sim KB, Koh CS, Shin YG, Shin T: Sodium salicylate-induced amelioration of experimental autoimmune encephalomyelitis in Lewis rats is associated with the suppression of inducible nitric oxide synthase and cyclooxygenases. Neurosci Lett. 2004 Feb 12;356(2):123-6. [Article]
  2. Graham GG, Scott KF: Mechanisms of action of paracetamol and related analgesics. Inflammopharmacology. 2003;11(4):401-13. [Article]
  3. Sun R, Carlson NG, Hemmert AC, Kishore BK: P2Y2 receptor-mediated release of prostaglandin E2 by IMCD is altered in hydrated and dehydrated rats: relevance to AVP-independent regulation of IMCD function. Am J Physiol Renal Physiol. 2005 Sep;289(3):F585-92. Epub 2005 Apr 19. [Article]
  4. Celik G, Pasaoglu G, Bavbek S, Abadoglu O, Dursun B, Mungan D, Misirligil Z: Tolerability of selective cyclooxygenase inhibitor, celecoxib, in patients with analgesic intolerance. J Asthma. 2005 Mar;42(2):127-31. [Article]
  5. Liu X, Lee TL, Wong PT: Cyclooxygenase-1 inhibition shortens the duration of diazepam-induced loss of righting reflex in mice. Anesth Analg. 2006 Jan;102(1):135-40. [Article]
  6. Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971 Jun 23;231(25):232-5. [Article]
  7. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [Article]
Pharmacological action
General Function
Prostaglandin-endoperoxide synthase activity
Specific Function
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and...
Gene Name
Uniprot ID
Uniprot Name
Prostaglandin G/H synthase 2
Molecular Weight
68995.625 Da
  1. Graham GG, Scott KF: Mechanisms of action of paracetamol and related analgesics. Inflammopharmacology. 2003;11(4):401-13. [Article]
  2. Fiebich BL, Chrubasik S: Effects of an ethanolic salix extract on the release of selected inflammatory mediators in vitro. Phytomedicine. 2004 Feb;11(2-3):135-8. [Article]
  3. Chae HJ, Chae SW, Reed JC, Kim HR: Salicylate regulates COX-2 expression through ERK and subsequent NF-kappaB activation in osteoblasts. Immunopharmacol Immunotoxicol. 2004 Feb;26(1):75-91. [Article]
  4. Wu KK: Aspirin and other cyclooxygenase inhibitors: new therapeutic insights. Semin Vasc Med. 2003 May;3(2):107-12. [Article]
  5. Elvira C, Gallardo A, Lacroix N, Schacht E, San Roman J: Incorporation of salicylic acid derivatives to hydrophilic copolymer systems with biomedical applications. J Mater Sci Mater Med. 2001 Jun;12(6):535-42. [Article]
  6. Vane JR: Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971 Jun 23;231(25):232-5. [Article]
  7. Zheng L, Howell SJ, Hatala DA, Huang K, Kern TS: Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy. Diabetes. 2007 Feb;56(2):337-45. [Article]
Pharmacological action
General Function
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
Specific Function
Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the in...
Gene Name
Uniprot ID
Uniprot Name
Aldo-keto reductase family 1 member C1
Molecular Weight
36788.02 Da
  1. Dhagat U, Carbone V, Chung RP, Matsunaga T, Endo S, Hara A, El-Kabbani O: A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase. Med Chem. 2007 Nov;3(6):546-50. [Article]


Pharmacological action
General Function
Steroid hydroxylase activity
Specific Function
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally un...
Gene Name
Uniprot ID
Uniprot Name
Cytochrome P450 2C9
Molecular Weight
55627.365 Da
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [Article]
  2. Bojic M, Sedgeman CA, Nagy LD, Guengerich FP: Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450. Eur J Pharm Sci. 2015 Jun 20;73:49-56. doi: 10.1016/j.ejps.2015.03.015. Epub 2015 Mar 31. [Article]


Pharmacological action
General Function
Toxic substance binding
Specific Function
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloid...
Gene Name
Uniprot ID
Uniprot Name
Serum albumin
Molecular Weight
69365.94 Da
  1. Bertucci C, Wainer IW: Improved chromatographic performance of a modified human albumin based stationary phase. Chirality. 1997;9(4):335-40. [Article]
  2. Xiao HR, Sheng LQ, Shi CH, Xu XL, Xie YS, Liu QL: [Fluorescence study on the interaction of salicylic acid and bovine serum albumin]. Guang Pu Xue Yu Guang Pu Fen Xi. 2004 Jan;24(1):78-81. [Article]
  3. Yin T, Wei W, Yang L, Liu K, Gao X: Kinetics parameter estimation for the binding process of salicylic acid to human serum albumin (HSA) with capacitive sensing technique. J Biochem Biophys Methods. 2007 Jun 10;70(4):587-93. Epub 2007 Jan 27. [Article]
  4. Yu T, Tao Z: [Fluorescence study on the interaction of salicylic acid and human serum albumin]. Guang Pu Xue Yu Guang Pu Fen Xi. 1999 Jun;19(3):453-5. [Article]


Pharmacological action
General Function
Sodium-independent organic anion transmembrane transporter activity
Specific Function
Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one ...
Gene Name
Uniprot ID
Uniprot Name
Solute carrier family 22 member 6
Molecular Weight
61815.78 Da
  1. Cihlar T, Ho ES: Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1. Anal Biochem. 2000 Jul 15;283(1):49-55. [Article]
  2. Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71. [Article]
  3. Race JE, Grassl SM, Williams WJ, Holtzman EJ: Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3). Biochem Biophys Res Commun. 1999 Feb 16;255(2):508-14. [Article]
  4. Uwai Y, Saito H, Inui K: Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter. Eur J Pharmacol. 2000 Dec 1;409(1):31-6. [Article]
  5. Apiwattanakul N, Sekine T, Chairoungdua A, Kanai Y, Nakajima N, Sophasan S, Endou H: Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Mol Pharmacol. 1999 May;55(5):847-54. [Article]
Pharmacological action
General Function
Sodium-independent organic anion transmembrane transporter activity
Specific Function
Not Available
Gene Name
Uniprot ID
Uniprot Name
Solute carrier family 22 member 10
Molecular Weight
60256.57 Da
  1. Youngblood GL, Sweet DH: Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney. Am J Physiol Renal Physiol. 2004 Aug;287(2):F236-44. Epub 2004 Apr 6. [Article]
Pharmacological action
General Function
Sodium-independent organic anion transmembrane transporter activity
Specific Function
Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenad...
Gene Name
Uniprot ID
Uniprot Name
Solute carrier family 22 member 8
Molecular Weight
59855.585 Da
  1. Cha SH, Sekine T, Fukushima JI, Kanai Y, Kobayashi Y, Goya T, Endou H: Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Mol Pharmacol. 2001 May;59(5):1277-86. [Article]
  2. Takeda M, Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine T, Endou H: Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71. [Article]
  3. Ohtsuki S, Kikkawa T, Mori S, Hori S, Takanaga H, Otagiri M, Terasaki T: Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier. J Pharmacol Exp Ther. 2004 Jun;309(3):1273-81. Epub 2004 Feb 4. [Article]
Pharmacological action
General Function
Sodium-independent organic anion transmembrane transporter activity
Specific Function
Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.
Gene Name
Uniprot ID
Uniprot Name
Solute carrier family 22 member 11
Molecular Weight
59970.945 Da
  1. Cha SH, Sekine T, Kusuhara H, Yu E, Kim JY, Kim DK, Sugiyama Y, Kanai Y, Endou H: Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. J Biol Chem. 2000 Feb 11;275(6):4507-12. [Article]
Pharmacological action
General Function
Sodium-independent organic anion transmembrane transporter activity
Specific Function
Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.
Gene Name
Uniprot ID
Uniprot Name
Solute carrier organic anion transporter family member 2B1
Molecular Weight
76709.98 Da
  1. Satoh H, Yamashita F, Tsujimoto M, Murakami H, Koyabu N, Ohtani H, Sawada Y: Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos. 2005 Apr;33(4):518-23. Epub 2005 Jan 7. [Article]
Pharmacological action
General Function
Symporter activity
Specific Function
Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucin...
Gene Name
Uniprot ID
Uniprot Name
Monocarboxylate transporter 1
Molecular Weight
53943.685 Da
  1. Tamai I, Sai Y, Ono A, Kido Y, Yabuuchi H, Takanaga H, Satoh E, Ogihara T, Amano O, Izeki S, Tsuji A: Immunohistochemical and functional characterization of pH-dependent intestinal absorption of weak organic acids by the monocarboxylic acid transporter MCT1. J Pharm Pharmacol. 1999 Oct;51(10):1113-21. [Article]
Pharmacological action
General Function
Sodium-independent organic anion transmembrane transporter activity
Specific Function
Mediates sodium-independent multispecific organic anion transport. Transport of prostaglandin E2, prostaglandin F2, tetracycline, bumetanide, estrone sulfate, glutarate, dehydroepiandrosterone sulf...
Gene Name
Uniprot ID
Uniprot Name
Solute carrier family 22 member 7
Molecular Weight
60025.025 Da
  1. Kobayashi Y, Ohshiro N, Shibusawa A, Sasaki T, Tokuyama S, Sekine T, Endou H, Yamamoto T: Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice. Mol Pharmacol. 2002 Jul;62(1):7-14. [Article]
  2. Sekine T, Cha SH, Tsuda M, Apiwattanakul N, Nakajima N, Kanai Y, Endou H: Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. FEBS Lett. 1998 Jun 12;429(2):179-82. [Article]
  3. Morita N, Kusuhara H, Sekine T, Endou H, Sugiyama Y: Functional characterization of rat organic anion transporter 2 in LLC-PK1 cells. J Pharmacol Exp Ther. 2001 Sep;298(3):1179-84. [Article]

Drug created at June 13, 2005 13:24 / Updated at July 22, 2024 03:26