Optic Neuritis (DBCOND0027863)

Identifiers

Synonyms
Optic neuritis / Unspecified optic neuritis / Optic neuritis (disorder) / Optic neuritis NOS / Optic neuritis, unspecified / Neuritis optic

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Corticotropin
A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Cortisone acetate
A steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
Dexamethasone
A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Hydrocortisone
A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
Methylprednisolone
A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
Prednisolone
A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
Prednisone
A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
Tetracosactide
A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02573792
Optical Coherence Tomography and Optic Neuritis (OCTON)No drug interventionsNot AvailableNot Availablecompleted
NCT01623076
The Longitudinal CONQUER Study of Rare Neuroimmunologic DisordersNo drug interventionsNot AvailableNot Availablerecruiting
NCT04942002
Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis Trialtreatment2 / 3unknown_status
NCT01274702
Visual Reconstitution Therapy After Optic NeuritisNo drug interventionstreatment2completed
NCT02004054
Interest of Dynamic Measures of the Pupil in Optic NeuritisNo drug interventionsNot AvailableNot Availablecompleted
NCT00000147
Longitudinal Optic Neuritis Study (LONS)treatmentNot Availableunknown_status
NCT03630497
BN201 SAD MAD Study in Healthy Subjectstreatment1completed
NCT02521311
Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)treatment2recruiting
NCT01451593
Neuroprotection With Phenytoin in Optic Neuritistreatment2completed
NCT00179478
Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosistreatment4completed
NCT04289909
Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics (RETIMUS)No drug interventionsotherNot Availableunknown_status
NCT03302585
High-Dose Vitamin D Induction in Optic Neuritistreatment2terminated
NCT00037115
Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event.treatment4withdrawn
NCT05017142
Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)No drug interventionsNot AvailableNot Availablerecruiting
NCT00000117
Intravenous Immunoglobulin Therapy in Optic NeuritisNo drug interventionstreatment3completed
NCT04257734
Epidemiologic and Clinical Characteristics of Optic Neuritis in ChinaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00856635
A Randomized, Double-blind, Placebo-controlled, Multicenter Study of the Effects of Glatiramer Acetate (GA) on the Retinal Nerve Fiber Layer (RNFL) and Visual Function in Patients With a First Episode of Acute Optic Neuritis (AON). (Octagon)treatment3completed
NCT01424735
TLR-9 Antagonism in Steroid Resistant Optic NeuritistreatmentNot Availablecompleted
NCT04042363
Effect of Transorbital Electrical STIMulation of Optic Nerve on Remyelination After an Acute Optic NeuritisNo drug interventionstreatmentNot Availableunknown_status
NCT01337986
Ampyra for Optic Neuritis in Multiple Sclerosistreatment2 / 3completed
NCT03586557
Effectiveness of Plasma Exchange in Treating With Severe Acute AQP4-Ab Positive Optic NeuritisNo drug interventionstreatmentNot Availableunknown_status
NCT00261326
Simvastatin Treatment of Patients With Acute Optic Neuritistreatment3unknown_status
NCT04792866
3D FLAIR Versus Coronal T2-WI MRI in Detecting Optic Neuritis (FLACON)No drug interventionsNot AvailableNot Availablecompleted
NCT02976766
Gypenosides Treatment for Optic NeuritisNo drug interventionstreatment2terminated
NCT01294176
Lipoic Acid as a Treatment for Acute Optic Neuritistreatment1completed
NCT03651362
Linking Optic Nerve MRI and the Retinal Axonal Loss After Optic NeuritisNo drug interventionsNot AvailableNot Availableunknown_status
NCT05540262
Edaravone in the Treatment of Aquaporin-4 Antibody-positive Optic NeuritistreatmentNot Availablerecruiting
NCT01987167
Defining the Functional and Neuro-Protective Potential of ACTHAR in Acute Optic Neuritistreatment0completed
NCT06389968
Light Stimulation to Improve Visual Function After Optic Neuritis in Persons With Multiple SclerosisNo drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT02894281
Pupillometry Dynamic Measures in Patients Without Ocular or Neurological DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT04131764
Diagnosis of ON With or Without MS or NMOSDNo drug interventionsNot AvailableNot Availableterminated
NCT03401879
Retinal Neuro-vascular Coupling in Patients With Multiple SclerosisNo drug interventionsbasic_scienceNot Availableunknown_status
NCT04793087
Post-COntrast 3D SE T1 Versus Coronal SE T1-WI MRI in Detecting Optic Neuritis (COCON)No drug interventionsNot AvailableNot Availablecompleted
NCT05605951
Acute Optic Neuritis Network: an International Study That Invesitages Subjects With a First-ever Episode of Acute Inflammation of the Optic NerveNo drug interventionsNot AvailableNot Availablerecruiting
NCT02886377
The Correlation Between AQP-4 Ab and the Visual Function of Patients With Demyelinating ON at OnsetNo drug interventionsNot AvailableNot Availableunknown_status
NCT01465893
Effect of Vitamin D on Retinal Changes in Patient With Optic Neuritis by Optic Coherence Tomographytreatment2unknown_status
NCT03753893
Ocular Manifestations in Rheumatic DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT01962571
Treatment of Optic Neuritis With Erythropoietin: a Randomised, Double-blind, Placebo-controlled Trialtreatment3completed
NCT03570385
Can Diffusion Tensor Imaging (DTI) of the Optic Ways Contributes to Predict the 6 Months Prognosis of Optic Neuritis (ON)?No drug interventionsotherNot Availablecompleted
NCT03345537
Initial Clinical Presentation of Inflammatory Optic Neuritis Associated or Not With Autoantibodies Anti-Myelin-oligodendrocyte-glycoproteinNo drug interventionsNot AvailableNot Availablecompleted
NCT02939937
Effect of Phenytoin on the Ganglion Cell Layer in Patients With Optic Neuritistreatment2completed
NCT05353413
Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.No drug interventionsdiagnosticNot Availableunknown_status
NCT01073813
Neuroprotection and Repair in Optic Neuritistreatment2terminated
NCT04762017
OCS-05 in Patients With Acute Optic NeuritisNo drug interventionstreatment2recruiting
NCT02864134
Optic Neuritis and Ganglion Cell LayerNo drug interventionsNot AvailableNot Availablecompleted
NCT03370965
Optic Neuritis Differential Diagnosis StudyNo drug interventionsdiagnosticNot Availablerecruiting
NCT06453694
Efgartigimod for the Treatment of Acute Optic Neuritistreatment2not_yet_recruiting
NCT01802489
Amiloride Clinical Trial In Optic Neuritistreatment2completed
NCT05487989
VIsual Pathways Model in Neuro-inflammatory DisordersNo drug interventionsNot AvailableNot Availablerecruiting
NCT00445367
Biobank For MS And Other Demyelinating DiseasesNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00624468
Atacicept in Subjects With Optic Neuritistreatment2terminated
NCT00000146
Optic Neuritis Treatment Trial (ONTT)treatment3unknown_status
NCT03963310
Optical Coherence Tomography and Optic Neuritis Not Related to Multiple SclerosisNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04148781
Fampridine-SR and Optic Neuritis Recoverytreatment0unknown_status
NCT00355095
Safety and Efficacy Study of Erythropoietin as add-on Therapy of Methylprednisolone to Treat Acute Optic Neuritisprevention2completed
NCT03451955
The Effect of a Gluten Free Diet on the Permeability of the Blood Brain Barrier in Patients With CISNo drug interventionstreatmentNot Availablecompleted
NCT01524250
Optic Neuritis Recovery After Oral or IV Corticosteroidstreatment2 / 3completed
NCT01774123
Optical Coherence Tomography in Multiple Sclerosis PatientsNo drug interventionsNot AvailableNot Availablecompleted