Status Epilepticus (DBCOND0028922)

Identifiers

Synonyms
Refractory seizure disorders / Status-epilepticus / Status Epileptics / Epilepticus Status / Status epilepticus / Prolonged seizure / Grand Mal Status Epilepticus / Status epilepticus grand mal / Grand mal status, epileptic / Grand mal status (disorder) / Convulsive status epilepticus

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Clobazam
A benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome.
Diazepam
A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.
Felbamate
An anticonvulsant used to treat severe epilepsy.
Fosphenytoin
An antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery.
Lacosamide
An antiepileptic drug used to treat partial-onset seizures and primary generalized tonic-clonic seizures.
Lorazepam
A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures.
Midazolam
A short-acting benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01355211
Putting Electroencephalography (EEG) in the Emergency DepartmentNo drug interventionsNot AvailableNot Availablecompleted
NCT06194747
Improving Status Epilepticus Treatment TimesNo drug interventionstreatmentNot Availablerecruiting
NCT06441760
Simulation Trial of Telemedical Support for ParamedicsNo drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT06590883
The STatus Epilepticus Prognosis StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00116064
Intranasal Lorazepam Versus Intramuscular Paraldehyde in Paediatric Convulsionstreatment3completed
NCT03378687
A Clinical Study of Children With Status Epilepticus in ChinaNo drug interventionsNot AvailableNot Availableunknown_status
NCT02381977
Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological AssessmentNo drug interventionsNot AvailableNot Availablecompleted
NCT02383745
EEG in In-hospital Patients With Seizure or Altered Mental StateNo drug interventionsNot AvailableNot Availablecompleted
NCT05267405
Mainz Epilepsy RegistryNo drug interventionsNot AvailableNot Availableunknown_status
NCT02958605
Smartphone Apps for Pediatric ResuscitationNo drug interventionstreatmentNot Availablecompleted
NCT02560597
Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of EpilepsyNo drug interventionstreatmentNot Availableterminated
NCT00004297
Phase III Randomized Study of Diazepam Vs Lorazepam Vs Placebo for Prehospital Treatment of Status Epilepticustreatment3completed
NCT06540378
Stiripentol for the Treatment of Refractory Status EpilepticusNot AvailableNot Availablecompleted
NCT00318578
Prognosis Factors Associated With Convulsive Status Epilepticus in AdultsNo drug interventionsNot AvailableNot Availablecompleted
NCT06401707
PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrestprevention2recruiting
NCT04758052
Tracheostomy With Bedside Simultaneous Gastrostomy Vs Usual Care Tracheostomy And Delayed Gastrostomy PlacementNo drug interventionstreatmentNot Availablewithdrawn
NCT05674552
Exogenous Ketone Esters for Refractory Status EpilepticsNo drug interventionstreatment2 / 3recruiting
NCT03245099
Management of Non Convulsive Status EpilepticusNo drug interventionsNot AvailableNot Availableunknown_status
NCT02344706
Diagnostic Value of Prehospital EEG in Non-convulsive Status EpilepticusNo drug interventionsNot AvailableNot Availableunknown_status
NCT05839418
Sustained Effort Network for Treatment of Status Epilepticus/European Academy of Neurology Registry on Refractory Status Epilepticus (SENSE-II/AROUSE)No drug interventionsNot AvailableNot Availablerecruiting
NCT00362141
Safety and Tolerability Study of Levetiracetam to Treat Patients With Status Epilepticustreatment2unknown_status
NCT05418634
Point-of-care EEG in the Pediatric Emergency DepartmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT01870024
Comparison Between Lorazepam, Clonazepam and Clonazepam + Fosphenytoin for the Treatment of Out-of-hospital Generalized Status Epilepticustreatment3completed
NCT00265616
Treatment of Refractory Status Epilepticustreatment3terminated
NCT03883516
Improving Emergency Management of Status EpilepticusNo drug interventionshealth_services_researchNot Availablerecruiting
NCT00343096
Randomized Trial Comparing 3 Routes of Delivering Lorazepam to Children.treatment3terminated
NCT06334796
Artificial Intelligence-powered Virtual Assistant for Emergency Triage in NeurologyNo drug interventionsdiagnostic0completed
NCT03350035
Intravenous Ganaxolone as Adjunctive Therapy to Treat Subjects With Status Epilepticustreatment2completed
NCT05647525
The Etiology of New-onset Status EpilepticusNo drug interventionsNot AvailableNot Availablecompleted
NCT05140265
De-identified UNMH EEG Corpus Database Creation With Fully De-identified Clinical InformationNo drug interventionsNot AvailableNot Availablerecruiting
NCT01796574
Ketogenic Diet for Refractory Status EpilepticusNo drug interventionstreatmentNot Availablecompleted
NCT04333082
Refractory Status Epilepticus Treatment: Quality and Efficacy of Coma InductionNo drug interventionsNot AvailableNot Availablecompleted
NCT03457831
Status Epilepticus in the Critically Ill PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT06017973
The Role of Imaging in the Diagnosis, Management and Prognosis of Possible Non-convulsive Status EpilepticusNo drug interventionsdiagnosticNot Availablerecruiting
NCT05851391
buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac ArrestNo drug interventionstreatment2recruiting
NCT04170491
EEG Monitoring for Refractory Status EpilepticusNo drug interventionsotherNot Availablesuspended
NCT05259891
eegCap Application in Paediatrics wiTh redUced GCS in REsusNo drug interventionsNot AvailableNot Availablecompleted
NCT05757544
Safety and Efficacy Study of IV Ganaxolone as Adjuvant Therapy for Established Status Epilepticus (ESE)treatment2withdrawn
NCT02726867
Levetiracetam, Lacosamide and Ketamine as Adjunctive Treatment of Refractory Status Epilepticustreatment3withdrawn
NCT04391569
Randomized Therapy In Status Epilepticustreatment3active_not_recruiting
NCT00114569
Lorazepam for the Treatment of Status Epilepticus in Childrentreatment1completed
NCT06067412
Efficacy of Phenytoin vs Levetiracetam in Status Epilepticus at Institute of Child Health,FaisalabadtreatmentNot Availablecompleted
NCT06067750
Comparison of Narcotrend and Cerebral Function Analysing Monitor in Intensive Care to Monitor Seizures and Deep SedationNo drug interventionsNot AvailableNot Availablerecruiting
NCT06403150
The Efficacy and Safety of Levetiracetam Versus Fosphenytoin in Convulsive Status Epilepticustreatment4enrolling_by_invitation
NCT04679623
Study of Midazolam in Healthy Adultstreatment1completed
NCT05591508
Ketogenic Diet for Status Epilepticus in Children Post Cessation of Convulsive Status EpilepticusNo drug interventionstreatmentNot Availablerecruiting
NCT04829838
Comparison of Efficacy of Phenytoin With Levetireacetam for the Management of Children With Status EpilepticusNo drug interventionstreatment4unknown_status
NCT03819543
SURESTEP: Transcranial Direct Current Stimulation in Super Refractory Status EpilepticusNo drug interventionstreatmentNot Availableterminated
NCT05934903
Feasibility Study: tDCS for Treatment of Refractory Status EpilepticusNo drug interventionsotherNot Availablerecruiting
NCT05491590
Patient-reported Outcome After Status EpilepticusNo drug interventionsNot AvailableNot Availablerecruiting
NCT05756621
Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac ArrestNot AvailableNot Availablerecruiting
NCT03562351
Seizure Rescue Medication: Caregiver Education in a Simulation SettingNo drug interventionspreventionNot Availablecompleted
NCT03905798
LORA-PITA IV General InvestigationNot AvailableNot Availablecompleted
NCT00621478
Efficacy and Safety Study Comparing Lorazepam and Diazepam for Children in the Emergency Department With Seizures (Status 2)treatment2 / 3completed
NCT06100978
Patient-reported Outcome and Patient-reported Experience After Status EpilepticusNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03154307
Repeated TMS at Low Frequencies to Reduce Seizure OccurrenceNo drug interventionstreatmentNot Availableterminated
NCT02995759
Creation, Implementation, and Analysis of a Seizure Action PlanNo drug interventionsNot AvailableNot Availablecompleted
NCT02056236
TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary ResuscitationtreatmentNot Availablecompleted
NCT02431663
Ketamine in Refractory Convulsive Status Epilepticustreatment3terminated
NCT05246566
Assessment of Adults Epidemiological Characteristics of Status Epilepticus in the French West Indies and in French GuianaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05000320
VIGAB-BIOSTAT: Neuronal Injury Panel SubstudyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00735527
Nasal Versus Venous Lorazepam for Control of Acute Seizures in Childrentreatment3completed
NCT04496076
COVID-19 Brain InjuryNo drug interventionsNot AvailableNot Availablecompleted
NCT06564662
Rapid-Response EEG in Children With Suspected Status EpilepticusNo drug interventionsNot AvailableNot Availablerecruiting
NCT02239380
Lorazepam for the Treatment of Status Epilepticus or Repetitive Status Epilepticus in Japantreatment3completed
NCT04926844
Effectiveness of Combined Levetiracetam and Midazolam in Generalized Convulsive Status Epilepticus in Childrentreatment2completed
NCT03742167
Pilot Simulation RCT of Telemedical Support for ParamedicsNo drug interventionshealth_services_researchNot Availablecompleted
NCT01268904
Safety and Efficacy of Intravenous Valproate in Pediatric Status Epilepticus and Acute Repetitive SeizuresNot AvailableNot Availableunknown_status
NCT04421846
Study of Pathophysiology of Status Epilepticus and Dysimmune EncephalitisNo drug interventionsbasic_scienceNot Availablerecruiting
NCT00809146
Paramedic Treatment of Prolonged Seizures by Intramuscular Versus Intravenous Anticonvulsant Medicationstreatment3completed
NCT02269137
Assessment of Severity and Prognosis for Patients With Status Epileptics(SE)No drug interventionsNot AvailableNot Availableunknown_status
NCT04287361
Clonazepam in Children Status EpilepticusNo drug interventionsNot AvailableNot Availablecompleted