Peptic Ulcer (DBCOND0031497)

Identifiers

Synonyms
Peptic Ulcers / Peptic ulcer / Ulcer Peptic / Gastric or peptic ulcer / Gastroduodenal ulcer / Ulcer gastroduodenal / Peptic ulcer, site unspecified / Peptic ulcer syndrome / Ulcer syndrome peptic / Peptic ulcer disease / Syndrome peptic ulcer / PUD / Peptic ulceration / GDU / Peptic ulcer (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Atropine
A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.
Esomeprazole
A proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
Glycopyrronium
An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia.
Hyoscyamine
An anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis.
Mepenzolate
A postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued.
Methscopolamine bromide
A muscarinic antagonist used to treat peptic ulcers, nausea, vomiting, and motion sickness.
Pipenzolate
An antimuscarinic agent indicated in the treatment of gastrointestinal motility disorders and arrhythmia.
No drug targets
Propantheline
An antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder.
Simethicone
An anti-flatulence agent used to relieve pressure, bloating, and symptoms referred to as gas.
No drug targets
Sucralfate
A gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01182597
Oral Versus IV Proton Pump Inhibitor in High-risk Bleeding Peptic Ulcers After Endoscopic Hemostasistreatment3unknown_status
NCT00137033
Celebrex Low Dose ASA Study Examining the Incidence of Gastroduodenal Ulcers in a Healthy Populationprevention4completed
NCT00261300
Long-term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708)treatment3completed
NCT00247130
Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcerprevention4withdrawn
NCT00374101
High Versus Standard Dose of Proton Pump Inhibitors (PPIs) in Peptic Ulcer Bleedingtreatment3completed
NCT01180179
PPI vs H2RA in Patients With Helicobacter Pylori-Negative Idiopathic Bleeding Ulcersprevention4completed
NCT03367897
Bleeding Ulcer and Erosions Study "BLUE Study"No drug interventionsNot AvailableNot Availablecompleted
NCT01838109
Postoperative Oral Nutritional Supplementation After Major Gastrointestinal SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT05237115
Helicobacter Pylori Eradication With Probiotics Combined With Triple Therapy Versus Bismuth-containing Quadruple Therapytreatment4completed
NCT00175032
A Comparison of Safety and Treatment in Subjects With Osteoarthritis Taking Low Dose Aspirintreatment3completed
NCT02342470
Efficacy and Safety of PMK-S005 in the Prevention of Recurrent Peptic Ulcer in Low-dose Aspirin UsersNo drug interventionsprevention2completed
NCT04702542
To Develop Methods for the Rehabilitation of Chronic Gastroduodenal Pathology in Children.No drug interventionssupportive_careNot Availableactive_not_recruiting
NCT00881413
Esomeprazole Versus Pantoprazole to Prevent Peptic Ulcer Rebleedingtreatment4withdrawn
NCT02961296
Helicobacter Pylori Antibiotic Susceptibility Testing of KoreaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00161096
On-Demand Use of Pantoprazole: Determinants for Chronic Use of Acid Suppressive Medicationtreatment3unknown_status
NCT00450658
Efficacy and Safety Study of HZT-501 in Reducing the Risk of Ibuprofen-associated Ulcersprevention3completed
NCT02084420
Efficacy/Safety Study as H. Pylori Eradication of Triple Therapy for 7 Days Treatmenttreatment3completed
NCT02001727
HEP-FYN 12-Years Follow-upNo drug interventionspreventionNot Availableunknown_status
NCT00854776
Peptic Ulcer Disease in Ischemic Heart Patients Taking Aspirin and Clopidogrel With or Without Proton Pump InhibitorpreventionNot Availableunknown_status
NCT06284876
Study to Evaluate the Efficacy and Safety of Ilaprazole 10 mg in Prevention NSAIDs Associated Peptic Ulcerprevention3not_yet_recruiting
NCT00471029
Compare Efficacy of Gastric Acid Suppression by Oral and Intravenous Administration of Esomeprazole in Patients With Peptic Ulcertreatment4unknown_status
NCT02551744
Proton Pump Inhibitor Versus Histamine-2 Receptor Antagonist for the Prevention of Recurrent Peptic UlcerspreventionNot Availablecompleted
NCT01353144
A Comparison of Two Therapeutic Strategies for the Treatment of Aspirin-associated Peptic Ulcerstreatment4completed
NCT00153712
Natural History of Non-steroidal Anti-inflammatory Drug and Non-Helicobacter Pylori in Bleeding Peptic UlcersNo drug interventionsNot AvailableNot Availablecompleted
NCT04784910
Study to Evaluate the Efficacy and Safety of DWP14012 in Prevention of NSAIDs Induced Peptic Ulcerprevention3completed
NCT03228095
Volatiles in Breath and Headspace Analysis - Diagnostic MarkersNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00534443
Importance of Cytokines in Peptic Ulcer Disease: Implications for TreatmentNo drug interventionsscreening4completed
NCT03814421
Efficacy of Low Dose Intravenous Proton Pump Inhibitor for Peptic Ulcer BleedingNo drug interventionstreatmentNot Availableunknown_status
NCT02296021
Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Bismuth-containing Quadruple Therapytreatment4completed
NCT01282853
Rapid Urease Test for Diagnosis of H. Pylori Infection in Patients With Peptic Ulcer BleedingNo drug interventionsdiagnosticNot Availablecompleted
NCT01142245
Effect of IV and Oral Esomeprazole in Prevention of Recurrent Bleeding From Peptic Ulcers After Endoscopic Therapytreatment3completed
NCT01828645
Residual Gastric Volume After the Ingestion of a Beverage Containing Carbohydrates Plus Whey ProteinNo drug interventionsNot Available2 / 3completed
NCT04025983
Effectiveness of GastimunHp Plus in Supporting the Treatment of Peptic Ulcer Disease With Helicobacter Pylori InfectionNo drug interventionssupportive_careNot Availableterminated
NCT00766961
TAE and Surgery in Patients With Peptic Ulcer Bleeding Uncontrolled by Endoscopic TherapyNo drug interventionstreatmentNot Availableterminated
NCT00977678
Drop in Gastroscopy - Experience After 9 MonthsNo drug interventionsNot AvailableNot Availablecompleted
NCT00325715
AGN 201904 Versus Esomeprazole in the Prevention of Aspirin-induced Stomach or Upper Intestinal Damage in Healthy Volunteersprevention1completed
NCT00920400
Diagnostic Value of Fecal Calprotectin in Disorders of the Upper Gastrointestinal TractNo drug interventionsNot AvailableNot Availablecompleted
NCT02648659
The Pilot Study on Tailored Eradication Therapy According to Clarithromycin Resistance in H.Pylori Patientstreatment4completed
NCT01667575
Efficiency Study of Clarithromycin and Bismuth-containing Quadruple Therapy to Treat H.Pyloritreatment4completed
NCT00152399
Study to Assess the Efficacy and Safety of Somatostatin in the Treatment of Acute Severe Upper Gastrointestinal BleedingNot Available2completed
NCT01979549
Adverse Events During Upper Gastrointestinal EndoscopyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01453036
Clarithromycin Resistant Tailored TherapyNo drug interventionstreatment4completed
NCT02436018
WEI NASAL JET for The Sedation of Outpatient Upper Gastrointestinal EndoscopyNo drug interventionspreventionNot Availableunknown_status
NCT01667718
Bismuth Improves the Efficacy of Levofloxacin-containing Triple Therapy for Helicobacter Pylori Treatmenttreatment4completed
NCT02581696
The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteersother1completed
NCT06439563
Study to Evaluate the Efficacy and Safety of JP-1366 in the Prevention of NSAIDs-Induced Peptic UlcersNo drug interventionsprevention3not_yet_recruiting
NCT00212225
Risk Factors for Gastric Disease in Pediatric Helicobacter Pylori (H. Pylori)No drug interventionsNot AvailableNot Availablecompleted
NCT02633930
Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Clarithromycin Quadruple Therapytreatment4completed
NCT01080326
Feasibility of Translumenal Endoscopic Omental Patch Closure of Perforated ViscusNo drug interventionsNot AvailableNot Availablecompleted
NCT00164866
Administration of High-Dose Intravenous Proton Pump Inhibitor for Upper Gastrointestinal Bleeding Prior to Endoscopytreatment4completed
NCT04636866
The Prevalence of Helicobacter Pylori in Shanghai, 2013 to 2019No drug interventionsNot AvailableNot Availablecompleted
NCT00441831
The Revolutions of Helicobacter Pylori Infection, Bacterial Density, and Histological Features After AntrectomyNo drug interventionsNot AvailableNot Availableunknown_status
NCT04140591
Proton Pump Inhibitor Plus Propranolol Versus Proton Pump Inhibitor Alone on Peptic Ulcer Healing in Patients With Liver Cirrhosistreatment2 / 3terminated
NCT01142180
Early Selective TAE to Severely Bleeding Peptic Ulcers After Their Initial Endoscopic HemostasisNo drug interventionstreatmentNot Availablecompleted
NCT02536989
Different Dose of Intravenous Omeprazole to Treat Bleeding Ulcer With Adherent Clottreatment4completed
NCT01667692
Aizthromycin or Clarithromycin in H-pylori Eradication Regimentreatment4completed
NCT04678492
Helicobacter Rescue Therapy With High-dose Esomeprazole and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapytreatment4completed
NCT03868267
Japanese Upper GI Symptoms Compared With Iranian and Canadian Patients PresentingNo drug interventionsNot AvailableNot Availableunknown_status
NCT02175901
Amoxicillin/Metronidazole Based Quadruple Therapy for Helicobacter Pylori Eradicationtreatment4completed
NCT05742568
Effects of High-dose Dual Therapy and Bismuth Quadruple Therapy for Helicobacter Pylori Eradication on Intestinal Microecologytreatment4recruiting
NCT01138969
Efficacy of Proton Pump Inhibitor in Prevention of Clopidogrel-related Peptic Ulcerprevention2completed
NCT00709046
High Dose Versus Standard Dose Proton Pump Inhibitor (PPI) in High-risk Bleeding Peptic Ulcers After Combined Endoscopic TreatmenttreatmentNot Availableunknown_status
NCT02418312
Efficacy of H2 Receptor Antagonist in Prevention of Thienopyridine-related Peptic UlcerpreventionNot Availablecompleted
NCT01376414
H. Pylori Testing for Patients With Non-specific Upper Abdominal Pain in the Emergency DepartmentNo drug interventionsNot AvailableNot Availablecompleted
NCT03736824
Correlation of Endoscopic Findings and Symptoms in Patients Undergoing the First Upper Gastrointestinal EndoscopyNo drug interventionsNot AvailableNot Availableunknown_status
NCT06077955
Ulcers Formation After Hand-Sewn vs Stapled Gastrojejunal Anastomosis In MGB.No drug interventionstreatmentNot Availablerecruiting