Chronic Sinusitis (DBCOND0031648)

Identifiers

Synonyms
Chronic Rhino-sinusitis / Sinusitis, Chronic Rhinosinusitis / Chronic Rhinosinusitis (Diagnosis) / Chronic Rhinosinusitis / Chronic sinusitis / Chronic sinusitis, unspecified / Chronic rhinosinusitis (disorder) / Unspecified sinusitis (chronic) / Sinusitis chronic NOS / Chronic sinusitis (disorder) / Highmoritis / Sinusitis / Sinusitis (disorder) / Sinus infection / Sinusitis NOS

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Beclomethasone dipropionate
An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
Dimetindene
A 1st generation selective H1 antagonist used topically as an antipruritic and orally to treat allergies.
Fluticasone propionate
A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05428410
Study on Biomarkers to Predict the Efficacy of IL-4R Monoclonal Antibody for Chronic Rhino-sinusitis With PolypsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01054703
Clinical Evaluation of the Ethmoid Sinus SpacerNo drug interventionstreatmentNot Availableterminated
NCT05295459
Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2)No drug interventionstreatment3active_not_recruiting
NCT05895929
The Role of IL5 in Epithelial Cell Integritybasic_science0recruiting
NCT05219968
Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in AdultsNo drug interventionstreatment3completed
NCT05925985
Propel Drug-Eluting Sinus Stent Family Open CohortNo drug interventionsNot AvailableNot Availablerecruiting
NCT04551703
Adrenaline Solution Irrigation and Bleeding During Sinus Surgeryprevention1completed
NCT04191590
Impact of Chronic Rhinosinusitis on the Index of Ciliary Beat Efficiency Using Fluorescent Nanosticks: (R-IMPAC)No drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT03563521
Identifying Serum Cytokine Profiles of Distinct Inflammatory Phenotypes in Severe AsthmaNo drug interventionsNot AvailableNot Availablecompleted
NCT04858802
A Clinical Evaluation of PROPEL® Contour Sinus ImplantNo drug interventionstreatmentNot Availablecompleted
NCT05035654
LYR-220 for Adult Subjects With Chronic Rhinosinusitis (BEACON Study)No drug interventionstreatment2completed
NCT03303677
Comparison of Topical Therapies in Post op Endoscopic Sinus Surgery Patientstreatment3withdrawn
NCT04805398
Subcutaneously CM310/Placebo in Patients With Chronic Rhinosinusitis With Nasal Polyposis (CROWNS-1)treatment2completed
NCT06502197
Comparative Analysis of Silastic Stenting in Sinus SurgeryNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04476628
Efficacy of Budesonide Via Delayed Release vs Immediate Releasetreatment0withdrawn
NCT05857228
Viral and Epigenetic Influences in CRSwNPNo drug interventionsNot AvailableNot Availablerecruiting
NCT04093193
Debridement and Functional Endoscopic Sinus SurgeryNo drug interventionstreatmentNot Availableunknown_status
NCT05220293
Treatment of Eosinophilic Chronic Rhinosinusitis Utilizing Betamethasone Dipropionate Nasal Creamtreatment1 / 2terminated
NCT03705793
Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitistreatment4completed
NCT03599271
A Clinical Evaluation of the Intersect ENT Sinus Device (ASCEND)No drug interventionstreatmentNot Availablecompleted
NCT03055507
Effect of Post-operative Ibuprofen After Surgery for Chronic Rhinosinusitistreatment2 / 3completed
NCT04041609
LYR-210 Depot (LYR-210) for Adult Subjects With Chronic Sinusitis (LANTERN Study)No drug interventionstreatment2completed
NCT03979209
Potential for Cortisol Suppression With the Use of High Volume Nasal Mometasone Irrigations in Varying Dosages.other1completed
NCT04048070
The Effect of Enhanced Recovery After Surgery in Endoscopic Sinus Surgerysupportive_careNot Availablecompleted
NCT03086070
Omeprazole 20 mg in Patients With Laryngopharyngeal reflux and Comorbid Chronic Rhinosinusitistreatment4completed
NCT04572516
Botulium Toxin Type A In Non Infectious Chronic RhinosinusitisNo drug interventionstreatment3completed
NCT06010316
A Prospective Single-center Cohort Study of Surgical Treatment of Chronic RhinosinusitisNo drug interventionsNot AvailableNot Availablerecruiting
NCT05009758
Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal PolypsNo drug interventionsscreeningNot Availablerecruiting
NCT03815435
The Influence of Blood Pressure Upon the Clarity of Surgical Field in Endonasal SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT05531630
Xylitol vs Saline Nasal Irrigations in CF-CRSNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT03963648
NO Measurements in Screening for Asthma and OSA, in Patients With CRSwNPNo drug interventionsdiagnosticNot Availableunknown_status
NCT03439865
Ivacaftor for Acquired CFTR Dysfunction in Chronic Rhinosinusitistreatment0recruiting
NCT03937427
Unified Airway ModelNo drug interventionsNot AvailableNot Availableunknown_status
NCT05061329
The Nasal Microbiome and Its Importance in DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT06191640
Sinus Disease in Young Children With Cystic FibrosisNot AvailableNot Availablerecruiting
NCT04171167
The Causal Relation of Nasal Nitric Oxide Levels to the Severity of Chronic Rhinosinusitis and Its Inflammatory PhenotypediagnosticNot Availableactive_not_recruiting
NCT03122795
Sinonasal Microbiome Transplant as a Therapy for Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)No drug interventionstreatmentNot Availablecompleted
NCT03970655
Functional Endoscopic Sinus Surgery Studyprevention1 / 2recruiting
NCT05882903
The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients With Chronic Rhinosinusitis Post Functional Endoscopic Sinus Surgery (FESS)treatment2recruiting
NCT03427502
Anterior Ethmoidal Nerve Block in Prevention of Postoperative AgitationpreventionNot Availablecompleted
NCT05553951
Adherence in Global AirwaysNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03587545
Study of Probiotic Potential of Lactobacillus Strains in the Upper Respiratory Tract After Nasal Spray ApplicationNo drug interventionsbasic_scienceNot Availableunknown_status
NCT03450083
Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposistreatment2completed
NCT04595461
Effect of Patient Education Videos on Perioperative Anxiety in Patients Undergoing Endoscopic Sinus SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT03935828
Effect of Topical Sinonasal AntibioticsNo drug interventionstreatment2unknown_status
NCT06368388
Bacteriophage Therapy for Difficult-to-treat Infections: the Implementation of a Multidisciplinary Phage Task ForceNo drug interventionsNot AvailableNot Availablerecruiting
NCT03673956
Topical Antibiotics in Chronic Rhinosinusitistreatment1 / 2completed
NCT04628442
Tissue Immune Interaction in Nasal PolyposisNo drug interventionsNot AvailableNot Availablerecruiting
NCT04097613
Betadine Rinses for Chronic Rhinosinusitis Prospective Cohort Studytreatment0completed
NCT05541419
Use of Budesonide Diluted to Maximum Clinical Treatment of Patients With Chronic Rhinosinusitis With Polyoposis.treatmentNot Availablerecruiting
NCT05287217
Post-operative Pain Control With Acetaminophen and Ibuprofen After Functional Endoscopic Sinus SurgeryNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT06437717
Role of Nanoemulsified Sesame Oil in Post-operative Care After Endoscopic Sinus SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT05400616
Nasal Microbiota Transfer Therapy in Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)No drug interventionstreatmentNot Availablerecruiting
NCT04469439
Impact of Sinus Surgery on Individuals With Cystic FibrosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT03188822
Steroid Delivery to the Frontal Sinus Opening With a Bioabsorbable Implant vs. a Bioabsorbable Nasal DressingNo drug interventionstreatmentNot Availableterminated
NCT03825757
Aggravated Airway Inflammation: Research on Genomics and Optimal Medical Care (AirGOs-medical)treatmentNot Availableactive_not_recruiting
NCT03369574
Study of Chronic Rhinosinusitis Symptoms in Asthma Patients Undergoing Treatment With ReslizumabNot AvailableNot Availablewithdrawn
NCT04514120
Alsaleh-Javer Endoscopic Sinus Score (AJESS) SystemNo drug interventionsdiagnosticNot Availableunknown_status
NCT03893227
Prevalence of Nasal Hyperreactivity in Chronic Upper Airway InflammationNo drug interventionsNot AvailableNot Availablecompleted
NCT01525862
XprESS Maxillary Balloon Dilation StudyNo drug interventionstreatmentNot Availablecompleted
NCT03243201
Silver Nanoparticle Investigation for Treating Chronic Sinusitistreatment1withdrawn
NCT04670172
Real-Life Chronic Rhinosinusitis Outcome RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT04242368
Hypertonic Versus Isotonic Saline Irrigations for Chronic Rhinosinusitistreatment2 / 3withdrawn
NCT05427695
Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitistreatment2not_yet_recruiting
NCT03878355
A Study of Different Endoscopic Surgery Procedures in Eosinophilic Chronic Rhinosinusitis With Nasal PolypsNo drug interventionstreatmentNot Availablecompleted
NCT04278950
Povidone-Iodine Rinses as an Adjuvant Therapy Post-OperativelytreatmentNot Availableunknown_status
NCT06642116
Evaluation of the Safety and Performance of a Bioresorbable Nasal Dressing Containing Mometasone FuroateNo drug interventionsdevice_feasibilityNot Availablenot_yet_recruiting
NCT05083741
Comparison of Chitodex Gel Vs NexFoam on Post-operative Outcomes in the Treatment of Chronic RhinosinusitisNo drug interventionsNot AvailableNot Availableterminated
NCT04836403
Validation of the Chinese Version of the Sinus and Nasal Quality of Life Survey (SN-5)No drug interventionsNot AvailableNot Availablecompleted
NCT05494164
Nigella Sativa for Selected Outcomes in Chronic RhinosinusitisNo drug interventionstreatmentNot Availablecompleted
NCT01988779
Oral Versus Topical Antibiotics for Chronic Rhinosinusitis Exacerbationstreatment3completed
NCT03229551
Xylitol for Chronic Sinusitistreatment2 / 3completed
NCT02284347
NuVent™ Revision StudyNo drug interventionstreatmentNot Availablecompleted
NCT05923047
Mepolizumab and In-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS). A Three Arm Study.treatment4not_yet_recruiting
NCT02548598
Analysis of Inflammation and Microbiome in Patients With Sinusitis and AsthmaNo drug interventionsNot AvailableNot Availablecompleted
NCT00799097
Determinants of Surgical Outcomes in Chronic SinusitisNo drug interventionsNot AvailableNot Availablecompleted
NCT05935683
Rhinosinusitis Italian Network: the Italian Registry for Severe, Uncontrolled Chronic RhinosinusitisNo drug interventionsNot AvailableNot Availablerecruiting
NCT02285283
Itraconazole for Fungal Sensitive Chronic Rhinosinusitis With Nasal Polypstreatment2 / 3terminated
NCT01255683
Oral Steroid Treatment for Chronic RhinosinusitisNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00899561
Computed Tomography (CT) Score and Histopathology of the Middle Turbinate in Chronic RhinosinusitisNo drug interventionsNot AvailableNot Availableunknown_status
NCT01084811
Chronic Rhinosinusitis: Biochemical Markers and BiofilmNo drug interventionsNot AvailableNot Availableunknown_status
NCT02106793
Mitomicin C for Prevention Postoperative Endoscopic Sinus Surgery Synechia and QOL in Chronic Rhinosinusitistreatment3completed
NCT02218307
The Use of Antibiotic Sinonasal Rinse After Sinus Surgerytreatment4completed
NCT03280537
A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitus With Nasal Polypstreatment3completed
NCT05167552
Treatment of Allergic Rhinitis and Chronic Polypous Rhinosinusitis With Olfactory Mucosa-derived Mesenchymal Stem CellsNo drug interventionstreatment1 / 2unknown_status
NCT01024075
Effect of Sinufoam-Dexamethasone Mixture on Post Endoscopic Sinus Surgery Outcomestreatment4unknown_status
NCT02746042
Sinupret Extract Coated Tablets in Chronic RhinosinusitisNo drug interventionstreatment3completed
NCT00318006
Study of Nasal Irrigation Versus Nasal Spray for Chronic Nasal and Sinus SymptomsNo drug interventionsNot Available4completed
NCT01332136
Determinants of Medical and Surgical Treatment Outcomes in Chronic SinusitisNo drug interventionsNot AvailableNot Availablecompleted
NCT01002313
Effect of Prednisone onTregs and TH17No drug interventionsNot AvailableNot Availablecompleted
NCT02367118
Prednisone in Chronic Rhinosinusitis Without Nasal Polypstreatment3unknown_status
NCT05198518
Microcurrent Device (TIVIC Health)No drug interventionstreatmentNot Availablecompleted
NCT05836935
Role of Imaging in Complications of SinusitisNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT05639686
TIVA vs TXA in Sinus Surgery to Evaluate Operative Blood Loss and Surgical Field QualitypreventionNot Availablerecruiting
NCT00871286
Point-of-Care Computed Tomography (CT) Chronic Rhinosinusitis StudyNo drug interventionsdiagnosticNot Availablecompleted
NCT01405339
Budesonide Application Via Mucosal Atomization Device as a Treatment for Chronic Rhinosinusitis When Utilized as a Topical Nasal Steroid SprayNo drug interventionstreatment1 / 2completed
NCT01179139
Pathogenesis of Chronic Sinusitis in Relationship to Tobacco Smoke ExposureNo drug interventionsbasic_scienceNot Availablecompleted
NCT03675022
Effect of Dupilumab on Sleep Apnea in Patients With Rhinosinusitistreatment0terminated
NCT02307825
Azithromycin for Patients With Chronic Rhinosinusitis Failing Medical and Surgical Therapytreatment4completed
NCT03478930
An Extension Study of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polypstreatment3completed
NCT01778465
Effect of Dietary Salicylate in Aspirin Exacerbated Respiratory DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT04703673
Sinolpan® Pharmacy Non-interventional Study - Quality of LiveNot AvailableNot Availablecompleted
NCT05883462
Paclitaxel-Coated Nasal Balloon for the Treatment of Recurrent Chronic Rhinosinusitis With or Without Nasal Polyps (FIH)No drug interventionstreatment0recruiting
NCT03960580
Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Rhinosinusitis Without the Presence of Nasal PolypsNo drug interventionstreatment3completed
NCT02182492
Efficacy of Macrolide and Glucocorticoid in the Treatment of Chronic Rhinosinusitis After Endoscopic Sinus SurgerytreatmentNot Availablecompleted
NCT03781804
Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Rhinosinusitis With or Without the Presence of Nasal PolypsNo drug interventionstreatment3completed
NCT06105346
Prevalence of ENT DiseseasNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01198912
Influence of Oral Doxycycline on Wound Healing After Endonasal Endoscopic Sinus Surgery for Chronic Rhinosinusitis With and Without Nasal Polyposis: a Double-blind Randomized Placebo-controlled Trialtreatment2completed
NCT03280550
A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polypstreatment3completed
NCT02347943
Global Sinus Surgery RegistryNo drug interventionsNot AvailableNot Availableterminated
NCT06108921
Efficacy and Safety of Xylitol Nasal Irrigation After Functional Endoscopic Sinus Surgerysupportive_careNot Availablecompleted
NCT01205984
Systemic Methylprednisolone in Chronic Rhinosinusitistreatment4completed
NCT03145051
Efficacy of Nasal Irrigation With Respimer® Netiflow® vs Saline Among Patients With Cystic Fibrosis and Chronic RhinosinusitisNo drug interventionstreatmentNot Availableunknown_status
NCT02720653
Determinants of Olfactory Dysfunction in Chronic RhinosinusitisNo drug interventionsNot AvailableNot Availableunknown_status
NCT04705805
Self-assessment of Olfactory Disorders for French Speaking PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01373528
Impact of Topical Sinonasal Budesonide Irrigation on Hypothalamic-Pituitary-Adrenal Axis FunctiontreatmentNot Availableterminated
NCT05450471
Effectiveness of Endonasal Polymeric Implant for Chronic Rhinosinusitistreatment3unknown_status
NCT06501807
BIOlogics in Severe Nasal POlyposis SurvEy.: a French RegistrytreatmentNot Availablenot_yet_recruiting
NCT04420052
Effects of Osteopathic Manipulative Treatment in Chronic Non-allergic RhinosinusitisNo drug interventionstreatmentNot Availablewithdrawn
NCT06457100
Esmolol Versus Lidocaine on the Quality of Postoperative Recovery in Patients Undergoing Functional Endoscopic Sinus Surgerytreatment1 / 2active_not_recruiting
NCT03607175
Adjunctive Treatment for Chronic Rhinosinusitis With Nasal Polyposistreatment2 / 3not_yet_recruiting
NCT02748070
Perioperative Oral Steroids for Chronic Rhinosinusitis Without Polyps (CRSsNP)treatmentNot Availablecompleted
NCT01943370
Early Saline Irrigation to Decrease Post-operative Endoscopic DebridementNo drug interventionsotherNot Availablecompleted
NCT01402349
Chronic Rhinosinusitis in a Danish Population: Evaluation of Causes of Disease, Progress and TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT01499719
Surgery Checklist and Process Improvement Surrounding Endoscopic Sinus SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT00847041
Microarray Analysis of Sinus Samples From Patients With and Without Chronic Rhinosinusitis.No drug interventionsNot AvailableNot Availablecompleted
NCT00265434
Nasal Inhalation of Dornase Alfa (Pulmozyme) in Patients With Cystic Fibrosis and Chronic Rhinosinusitistreatment3completed
NCT01254916
The Sinonasal Outcome Test - 22, Validated for Danish PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00947986
Mucociliary Clearance Time in Chronic Rhinosinusitis (CRS) Patients After Sinus SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT04131686
NAC Inhalation in the Treatment Of Symptomatic acuTe rhinosinUSitisNo drug interventionsNot AvailableNot Availablecompleted
NCT05015530
Impact of Symbiofilm On Nasal MicrobiotaNo drug interventionsNot AvailableNot Availablerecruiting
NCT01455948
Canadian Health Economics, Outcome, and Effectiveness Comparison of Treatment in Patients With Chronic RhinosinusitisNo drug interventionshealth_services_researchNot Availableterminated
NCT01214057
Total Intravenous Anesthesia (TIVA) vs. Inhaled Anesthesia for Endoscopic Sinus Surgery.treatmentNot Availableterminated
NCT01255566
Medical Therapy Versus Sinus Surgery for Chronic Rhinosinusitis: A Prospective, Multi-institutional StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT04048174
Safety and Efficacy of Lactococcus Lactis Probiotic Bacteria for the Treatment of Chronic RhinosinusitisNo drug interventionstreatmentNot Availablecompleted
NCT02692794
Large Scale Cerebral Oximetry During Sinus EndoscopyNo drug interventionsNot AvailableNot Availablecompleted
NCT00396162
Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitistreatment4completed
NCT01066104
Subcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposistreatment2completed
NCT04117646
Validity of the French Version of the Child's Chronic Rhinosinusitis QuestionnaireNo drug interventionsNot AvailableNot Availablecompleted
NCT01391910
Response Shift in Sinus Surgery OutcomesNo drug interventionsNot AvailableNot Availablecompleted
NCT06439381
Long-term Safety and Efficacy of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal PolypsNo drug interventionstreatment2recruiting
NCT02154555
A Randomized Controlled Trial Evaluating Postoperative Debridement Following Endoscopic Sinus SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT01575223
Saline Irrigation After Surgery in Patients With Chronic SinusitisNo drug interventionstreatment4completed
NCT03614923
Etokimab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)treatment2completed
NCT03704415
Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT04362501
Efficacy of Dupilumab for Patients With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)treatment2recruiting
NCT01894503
Safety and Performance of the Steroid-Releasing S8 Sinus Implanttreatment2completed
NCT05983003
Research on Identifying and Treatment Prognosis of Chronic Rhinosinusitis Based on Image and Sequencing DataNo drug interventionsNot AvailableNot Availablecompleted
NCT03174483
Radiologic Scoring of Patients With Chronic Sinusitis and Nasal PolypstreatmentNot Availableunknown_status
NCT03519061
Impact of Budesonide Irrigations on Patients With Chronic Rhinosinusitis and Impact on Sinus Surgery Ratestreatment2 / 3withdrawn
NCT06070311
Wound Healing After Endoscopic Sinus SurgerytreatmentNot Availablenot_yet_recruiting
NCT04645511
Balloon Sinuplasty Efficiency in Maxillary Rhinosinusitis.No drug interventionstreatmentNot Availablerecruiting
NCT00939471
Safety and Efficacy of Balloon Sinuplasty in Pediatric SinusitisNo drug interventionstreatmentNot Availablecompleted
NCT04163978
Nitric Oxide Releasing Sinus Irrigation (NOSi) to Treat Recalcitrant Chronic Rhinosinusitis (RCRS)treatment2completed
NCT05157685
Evaluation of the Efficacy of Azithromycin in Idiopathic Purulent Oedematous Sinusitis in Adultstreatment3recruiting
NCT00447837
Evaluating SPRC-AB01 in Post-Surgical Subjects With Chronic Sinusitistreatment2completed
NCT01706952
Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgeryother4completed
NCT01007799
Vitamin D for Chronic SinusitisNo drug interventionstreatmentNot Availablecompleted
NCT02812199
Efficacy of Post-FESS Implantation of Composite Removable Sinus Stent to Prevent Post-Operative ComplicationstreatmentNot Availableunknown_status
NCT06398899
Sugammadex v.s. Neostigmine/GlycopyrrolatepreventionNot Availablenot_yet_recruiting
NCT01525849
Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-UpNo drug interventionstreatmentNot Availablecompleted
NCT02291549
S8 Sinus Implant in Chronic Sinusitis Patients With Recurrent Nasal Polypstreatment3completed
NCT01732536
Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polypstreatment2 / 3completed
NCT04291118
Assessing Improvement in Cognitive Deficit in CRS in Patients Treated With Medical Vs Surgical ManagementotherNot Availableunknown_status
NCT01854619
Photodynamic Therapy for the Treatment of Chronic RhinosinusitisNo drug interventionstreatmentNot Availableunknown_status
NCT03154541
SynRinse Irrigation Pilot (SIP) TrialNo drug interventionstreatment1 / 2completed
NCT00671541
Nasospore Stent For Use in Enodscopic Sinus Surgerytreatment4withdrawn
NCT02981017
Improvement of Outcomes in Draf III/Endoscopic Modified Lothrop ProcedureNo drug interventionstreatmentNot Availablewithdrawn
NCT01066416
Effects of Endoscopic Sinus Surgery for Chronic Sinusitis on Asthma ControlNo drug interventionstreatmentNot Availableterminated
NCT04060316
GLS-1200 Topical Nasal Spray to Prevent Sinusitis After Endoscopic Sinus Surgerytreatment2not_yet_recruiting
NCT05369039
Roflumilust in Chronic Rhinosinusitis With Nasal Polyposis.treatment2unknown_status
NCT00626366
Distribution of Topical Nasal Medication Within the Nasal Cavity and Sinuses by Radiographic ComparisonotherNot Availablecompleted
NCT02228720
Clinical Evaluation of Propel Nova Sinus Implant in Peripheral Sinus OstiaNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT02967731
480 Biomedical Sinus Drug Depottreatment1completed
NCT06036927
A Clinical Study of TQC2731 Injection in the Treatment of Chronic Rhinosinusitis With Nasal PolypsNo drug interventionstreatment2recruiting
NCT06198894
Steroid-eluting Sinus Stent for Chronic Rhinosinusitis Patients With Uncontrolled Postoperative SymptomstreatmentNot Availablerecruiting
NCT00231062
Clinical Evaluation to Confirm Safety and Efficacy of Sinuplasty in the Paranasal Sinuses (CLEAR)No drug interventionstreatment3completed
NCT05345080
Houston "Breathe Easy" Healthy Homes-Based Model for Multifamily Rental CommunitiesNo drug interventionstreatmentNot Availableunknown_status
NCT00962689
Clinical Study to Improve Diagnosis and Treatment of SinusitisNo drug interventionsNot AvailableNot Availablecompleted
NCT05156801
Efficacy of ArchSinus, NasoPore & Propel to Prevent Post-Surgical MT Lateralization and Improve Symptomatic OutcomesNo drug interventionstreatmentNot Availableunknown_status
NCT00924404
Xylitol Versus Saline in Chronic SinusitistreatmentNot Availablecompleted
NCT01197612
Nasal Packing as a Drug Delivery System Postoperatively in Chronic Sinusitis With Polyposistreatment3completed
NCT00852410
The Hemostatic and Hemodynamic Effects of Adrenaline During Endoscopic Sinus Surgerytreatment3unknown_status
NCT00671281
The Effect of Tranexamic Acid on Intraoperative and Post-Operative Bleeding in Functional Endoscopic Sinus SurgerytreatmentNot Availablewithdrawn
NCT06272123
Endotypic Stability in CRSNo drug interventionsNot AvailableNot Availablerecruiting
NCT00140608
Efficacy of Seprapack Sinus Dressing Versus No Dressing in the Prevention of Intranasal Adhesions Following Sinus SurgeryNo drug interventionstreatmentNot Availableterminated
NCT01185808
Vitamin D Supplementation in Chronic Rhinosinusitis With Nasal PolypstreatmentNot Availablewithdrawn
NCT01608308
Intraoperative and Post-operative Analgesic Effect of IV Acetaminophen for Sinus Surgerysupportive_careNot Availablecompleted
NCT02687438
The PIO (Propel In Office) III Study of In-office Placement of a Steroid-Eluting Implant Immediately Following Ethmoid Sinus SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT06020690
A Clinical Study to Evaluate the Safety and Effectiveness of Novabel Bioabsorbable Steroid-releasing Stent for the Chronic SinusitisNo drug interventionstreatmentNot Availablerecruiting
NCT00841802
Chronic Rhinosinusitis With or Without Nasal Polyps Steroid Studytreatment4withdrawn
NCT01706484
Efficacy and Safety of Two Dosages of a Herbal Medicinal Product (Dry Extract BNO 1016) in Chronic RhinosinusitisNo drug interventionstreatment3completed
NCT00705354
Pilot Study To Evaluate A Pharmacologically Active Nasal Sponge Following Endoscopic Sinus SurgerytreatmentNot Availablewithdrawn
NCT01253577
A Clinical Evaluation of a Steroid-Coated Sinus Stent When Used Following Functional Endoscopic Sinus Surgery in Patients With Chronic SinusitisNo drug interventionstreatment3completed
NCT00912405
Clinical Evaluation of the Steroid-Eluting Sinexus Intranasal Splint When Used Following Functional Endoscopic Sinus Surgery (FESS) in Patients With Chronic SinusitisNo drug interventionssupportive_careNot Availablecompleted
NCT05924711
"Association of Peri-implantitis and Maxillary Sinusitis: a Case-control Study".No drug interventionsNot AvailableNot Availablerecruiting
NCT00939393
Balloon Sinus Dilation In Office or ORNo drug interventionshealth_services_researchNot Availablecompleted
NCT00754793
Sinusitis and Facial Pain Disorders Anti-Depression Trialtreatment4terminated
NCT03336671
Management of Pediatric Chronic Rhinosinusitis in Asthmatic ChildrenNo drug interventionstreatmentNot Availableterminated
NCT04678856
Dupilumab in CRSsNPtreatment2completed
NCT04915456
Effect of Postoperative Additive Systemic Steroids in CRSwNPtreatment4completed
NCT00603785
Effects of Anti-IgE Antibody Omalizumab on Patients With Chronic Sinusitistreatment4withdrawn
NCT03903432
The Feasibility of Using MRI During ESSNo drug interventionsotherNot Availableunknown_status
NCT00840970
A Clinical Evaluation of the Sinexus Intranasal Splint Following Functional Endoscopic Sinus Surgery in Patients With Chronic RhinosinusitisNo drug interventionstreatmentNot Availablecompleted
NCT02562924
The Efficacy of MEDIHONEY® for Chronic Rhinosinusitis With Nasal Polyposis After Functional Endoscopic Sinus SurgerytreatmentNot Availablecompleted
NCT00880516
Genetic Factors in Chronic SinusitisNo drug interventionsNot AvailableNot Availablerecruiting
NCT00410735
Study of ONO-1078 in Patients With Chronic Sinusitistreatment3completed
NCT05454163
Post-radiotherapy Rhinosinusitis in ChildrenNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04418622
Evolution of the Endonasal Microbiota in Patients With Chronic RhinosinusitisNo drug interventionsNot AvailableNot Availablecompleted
NCT01700725
Gulf War Illness Nasal Irrigation Studytreatment2completed
NCT04754230
Effect of Tranexamic Acid on Postoperative Bleeding Following Sinus and Nasal Surgeryprevention4completed
NCT04374448
Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base SurgeryNo drug interventionsotherNot Availablenot_yet_recruiting
NCT01569048
Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgeryprevention4completed
NCT01430026
Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic RhinosinusitisNo drug interventionsNot AvailableNot Availablecompleted
NCT00425620
Amphotericin B Suspension in Refractory Chronic Sinusitistreatment3completed
NCT04187976
Eosinophils Endotypes in Chronic Airway Inflammatory DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
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The Effect of Modified Radical Endoscopic Sinus Surgery on Eosinopilic Chronic Rhinosinusitus With Nasal PolypsNo drug interventionstreatmentNot Availablerecruiting
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Safety Evaluation of Repeat Placement of the S8 Sinus Implant in Chronic Sinusitis Patients With Nasal Polyps (ENCORE)No drug interventionstreatment3completed
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Microbiota Transfer for Chronic RhinosinusitisNo drug interventionstreatmentNot Availablerecruiting
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Esmolol vs. Labetalol in Endoscopic Sinus Surgerytreatment2completed
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Safety and Efficacy of the Propel Mini and Propel Nova Steroid-Eluting Sinus Implant in Frontal SinusNo drug interventionstreatment3completed
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Comparison of Two Steroid Nasal Implants Following Endoscopic Sinus Surgery for Chronic Rhinosinusitistreatment0withdrawn
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Treatment With Mepolizumab on Patients With Severe Refractory Eosinophilic Asthma With or Without CRSwNP.Not AvailableNot Availablerecruiting
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In-office Placement of the Propel Mini Sinus Implant in the Frontal Sinus OstiaNo drug interventionstreatmentNot Availablecompleted
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Postoperative Systemic Corticosteroids When Utilizing a Steroid-Eluting Spacer Following Endoscopic Sinus SurgeryNo drug interventionstreatmentNot Availablecompleted
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Results of Endoscopic Sinus Surgery in Management of Ophthalmological Complications of Chronic Rhino SinusitisNo drug interventionstreatmentNot Availablecompleted