Lymphoma, Diffuse (DBCOND0036855)
Identifiers
- Synonyms
- Lymphosarcoma / Diffuse lymphoma / Malignant lymphoma - mixed small and large cell (disorder) / Lymphosarcoma -RETIRED- / Lymphosarcoma (disorder) / Non-Hodgkin lymphoma, unspecified / Mantle cell lymphoma / Non-Hodgkin lymphoma (morphologic abnormality) / Non-Hodgkin's lymphoma / Non-Hodgkin's lymphoma NOS / Malignant lymphoma - small cleaved cell (disorder) / Lymphoma, Non-Hodgkin / Non-Hodgkin's lymphoma (disorder) / Lymphoma (non-Hodgkin's)
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Chlorambucil A chemotherapy agent used in the management of chronic lymphocytic leukemia and malignant lymphomas.Daunorubicin An anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia.- DNAtarget
- Cytochrome P450 3A5enzyme
- NADPH--cytochrome P450 reductaseenzyme
- ATP-dependent translocase ABCB1transporter
- Multidrug resistance-associated protein 1transporter
- ATP-binding cassette sub-family C member 6transporter
- ATP-binding cassette sub-family C member 10transporter
- Broad substrate specificity ATP-binding cassette transporter ABCG2transporter
- DNA topoisomerase 2-alphatarget
- DNA topoisomerase 2-betatarget
- Cytochrome P450 1B1enzyme
- Cytochrome P450 3A4enzyme
- Aldo-keto reductase family 1 member B1enzyme
- Carbonyl reductase [NADPH] 1enzyme
- Carbonyl reductase [NADPH] 3enzyme
Mechlorethamine An antineoplastic agent used to treat Hodgkin's disease, lymphosarcoma, and chronic myelocytic or lymphocytic leukemia.- DNAtarget
- Cholinesteraseenzyme
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT00455897 CHOP-Rituximab Augmented With GM-CSF in Patients With Previously Untreated Diffuse Large B Cell Non-Hodgkin's Lymphoma treatment 2 terminated NCT00596804 Safety Study of Different Doses of hA20 (Veltuzumab) in CD20+ Non-Hodgkin's Lymphoma treatment 1 / 2 completed