Nasal Allergies (DBCOND0054452)

Identifiers

Synonyms

Nasal Allergy / Allergic rhinosinusitis / Allergic rhinitis, cause unspecified / Allergic rhinitis, unspecified / Rhinallergosis / Rhinitis allergic / Rhinitis allergic NOS / Seasonal allergic rhinitis (disorder) [Ambiguous] / (Allergic rhinitis: [NOS] or [perennial] or [seasonal]) or (vasomotor rhinitis) / Allergic rhinitis / Rhinitis: [perennial] or [allergic] / Allergic rhinitis (disorder) / Rhinitis, Allergic / Allergic rhinitis NOS (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Naphazoline	A sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion.	Alpha-1A adrenergic receptortarget Alpha-2A adrenergic receptortarget D(2) dopamine receptortarget
Pseudoephedrine	An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis.	Alpha-1A adrenergic receptortarget Alpha-2A adrenergic receptortarget Beta-2 adrenergic receptortarget Amine oxidase [flavin-containing] Aenzyme Beta-1 adrenergic receptortarget Sodium-dependent dopamine transportertarget Sodium-dependent noradrenaline transportertarget Sodium-dependent serotonin transportertarget Nuclear factor of activated T-cells, cytoplasmic 1target Tumor necrosis factortarget Nuclear factor NF-kappa-B p105 subunittarget activator protein 1target Interleukin-2target Albumincarrier Sodium-dependent noradrenaline transportertransporter Sodium-dependent dopamine transportertransporter Sodium-dependent serotonin transportertransporter D(2) dopamine receptortarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT01454505	Safety and Efficacy of AL-53817 Nasal Spray Solution	No drug interventions	treatment	1	completed
NCT01494948	Innate Immunity and the Allergic Response	No drug interventions	basic_science	Not Available	completed
NCT06021002	Nasal Immune Challenge Study	Resiquimod	basic_science	Not Available	recruiting
NCT05301647	Mometasone Furoate Nasal Spray in Italian Children	No drug interventions	Not Available	Not Available	completed
NCT01925729	TransMEM Gas Exchange -- Project 1, Aim 2	Histamine Oxymetazoline Pseudoephedrine	basic_science	1	completed
NCT03039101	Leukotriene Antagonism in Recruitment of CD49d Expressing Neutrophils in Atopic Subjects	Montelukast	basic_science	Not Available	completed