Metastatic Liposarcoma (DBCOND0055525)
Identifiers
- Synonyms
- Liposarcoma metastatic
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Eribulin A microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma.- Apoptosis regulator Bcl-2target
- Tubulin beta-1 chaintarget
Trabectedin An alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma).- Cytochrome P450 3A4enzyme
- Cytochrome P450 2C9enzyme
- Cytochrome P450 2D6enzyme
- Cytochrome P450 2E1enzyme
- Cytochrome P450 2C19enzyme
- DNAtarget
- Prostaglandin G/H synthase 1enzyme
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT03074318 Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery treatment 1 / 2 terminated NCT06414434 BTX-A51 in Patients with Liposarcoma No drug interventions treatment 1 recruiting NCT03009201 Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery No drug interventions treatment 1 completed NCT02500797 Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery No drug interventions treatment 2 completed NCT02978859 Sitravatinib in Advanced Liposarcoma and Other Soft Tissue Sarcomas No drug interventions treatment 2 completed NCT01506596 Study of Pazopanib in the Treatment of Surgically Unresectable or Metastatic Liposarcoma No drug interventions treatment 2 completed NCT02357810 Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas No drug interventions treatment 2 completed