NCT06076837
The Seven Trial: Exploiting the Unfolded Protein Response treatment 1 not_yet_recruiting NCT05077800
FOLFIRINOX + 9-Ing-41 + Losartan In Pancreatic Cancer treatment 2 recruiting NCT04150042
SHARON: A Clinical Trial for Metastatic Cancer With a BRCA or PALB2 Mutation Using Chemotherapy and Patients' Own Stem Cells treatment 1 recruiting NCT01053013
Open-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic/Colorectal Cancer No drug interventions treatment 2 completed NCT03633734
Efficacy Evaluation of Sequential Treatment With AG and Modified Folfirinox in Metastatic Pancreatic Adenocarcinoma No drug interventions treatment 1 / 2 recruiting NCT03127124
QUILT-2.022 NANT-008 in Combination w/ 5-fluorouracil, Bevacizumab, Leucovorin & Oxaliplatin in Subjects With Pancreatic Cancer treatment 1 / 2 withdrawn NCT02195180
Efficacy and Safety of L-asparaginase Encapsulated in RBC Combined With Gemcitabine or FOLFOX in 2nd Line for Progressive Metastatic Pancreatic Carcinoma treatment 2 completed NCT05360264
tailOred dRug repurposIng of dEcitabine in KRAS-dependeNt refracTory pAncreaTic cancEr treatment 2 recruiting NCT06051851
Penpulimab Combined With Anlotinib and Nab-paclitaxel Plus Gemcitabine as First-line Treatment for Advanced Metastatic Pancreatic Cancer treatment 2 recruiting NCT06006728
Real World Efficacy, Safety of Nanoliposomal Irinotecan With Fluorouracil and Folinic Acid in Metastatic Pancreatic Cancer After Previous Gemcitabine-based Therapy No drug interventions Not Available Not Available completed NCT06396637
PD-1 Antibody and Sapropterin Dihydrochloride in Patients With PDAC No drug interventions treatment 2 recruiting NCT03529175
Scheduling Nab-paclitaxel With Gemcitabine No drug interventions treatment 2 completed NCT02179970
To Assess the Safety of Continuous IV Administration of Plerixafor in Patients With Advanced Pancreatic, Ovarian and Colorectal Cancers No drug interventions treatment 1 completed NCT01715142
Effect on Tumor Perfusion of a Chemotherapy Combining Gemcitabine and Nab-paclitaxel (Abraxane) in Pancreatic Cancer No drug interventions treatment 0 completed NCT03213626
Cabozantinib and Erlotinib for Patients With EGFR and c-Met Co-expressing Metastatic Pancreatic Adenocarcinoma No drug interventions treatment 2 terminated NCT01825603
ADH-1, Gemcitabine Hydrochloride & Cisplatin in Treating Metastatic Pancreatic or Biliary Tract Cancer No drug interventions treatment 1 completed NCT04058964
Pembrolizumab and PEGPH20 in Treating Patients With Metastatic Pancreatic Cancer No drug interventions treatment 2 withdrawn NCT04191421
Siltuximab and Spartalizumab in Patients With Metastatic Pancreatic Cancer No drug interventions treatment 1 / 2 completed NCT03006302
Epacadostat, Pembrolizumab, and CRS-207, With or Without CY/GVAX Pancreas in Patients With Metastatic Pancreas Cancer No drug interventions treatment 2 active_not_recruiting NCT02048384
A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer No drug interventions treatment 1 completed NCT02504333
Phase I/II Study of Nab-paclitaxel and Gemcitabine Followed by AG-mFOLFOX in Patients With Metastatic Pancreatic Adenocarcinoma treatment 1 / 2 completed NCT03974854
Evaluation of Polychemotherapy With XELOXIRI-3 in Elderly or Frail Patients With Advanced Pancreatic Adenocarcinoma treatment 2 terminated NCT04348045
Personalized Maintenance Therapy for m-PDAC Using Olaparib or Selumetinib + Durvalumab, Based on BRCAness and KRAS Status. treatment 2 active_not_recruiting NCT04132505
Binimetinib and Hydroxychloroquine in Treating Patients With KRAS Mutant Metastatic Pancreatic Cancer treatment 1 recruiting NCT04514497
Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer treatment 1 active_not_recruiting NCT06018883
Vitamin C to Chemotherapy Related Anemia in Pancreatic Cancer treatment 3 recruiting NCT03257761
Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer treatment 1 active_not_recruiting NCT01510561
A Study of Fractionated 90Y-hPAM4 Plus Gemcitabine in Pancreatic Cancer Patients Receiving at Least 2 Prior Therapies. treatment 1 withdrawn NCT04387071
CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma treatment 1 / 2 terminated NCT03611556
MEDI9447(Oleclumab) Pancreatic Chemotherapy Combination Study. treatment 1 / 2 completed NCT04050085
SD-101, Nivolumab, and Radiation Therapy in Treating Patients With Chemotherapy-Refractory Metastatic Pancreatic Cancer treatment 1 completed NCT06576115
Gemcitabine, Nab-paclitaxel Plus the TheraBionic P1 (an Amplitude-Modulated Radiofrequency Electromagnetic Fields) Device to Treat Metastatic Pancreatic Cancer treatment 2 not_yet_recruiting NCT01760252
Neoadjuvant CAPOXIRI Chemotherapy in the Treatment of Pancreatic Adenocarcinoma Protocol other 2 terminated NCT05383352
A Study to Compare Onivyde Manufactured at Two Different Production Sites in Adult Participants With Advanced Cancer in the Pancreas treatment 1 active_not_recruiting NCT02847000
p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Pancreatic Cancer treatment 0 completed NCT04652206
Clinical Trial to Investigate Safety, Tolerability and MTD for SCO-101 in Combination With Gemcitabine and Nab-paclitaxel in Inoperable Pancreatic Cancer Patients. treatment 1 / 2 unknown_status NCT02498613
A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors treatment 2 active_not_recruiting NCT04616534
Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors treatment 1 active_not_recruiting NCT04975516
Standard of Care Chemotherapy With or Without Stereotactic Body Radiation Therapy for Oligometastatic Pancreatic Cancer No drug interventions treatment 2 recruiting NCT02495896
Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors treatment 1 terminated NCT02117258
Z-360 Plus GEM in Subjects With Metastatic Pancreatic Adenocarcinoma No drug interventions treatment 2 completed NCT02650635
TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurrent, or Progressive Solid Tumors treatment 1 terminated NCT03368963
TAS102 in Combination With NAL-IRI in Advanced GI Cancers treatment 1 / 2 recruiting NCT04115163
Biologically Optimized Infusion Schedule of Gemcitabine and Nab-Paclitaxel for the Treatment of Metastatic Pancreatic Cancer treatment 2 recruiting NCT02826486
Study Assessing Safety and Efficacy of Combination of BL-8040 and Pembrolizumab in Metastatic Pancreatic Cancer Patients treatment 2 completed NCT05417386
FOLFIRINOX + NIS793 in Pancreatic Cancer treatment 1 terminated NCT01959139
S1313, PEGPH20 in Treating Patients With Newly Diagnosed Metastatic Pancreatic Cancer treatment 1 / 2 completed NCT02985125
LEE011 Plus Everolimus in Patients With Metastatic Pancreatic Adenocarcinoma Refractory to Chemotherapy treatment 1 / 2 unknown_status NCT06524973
Telehealth Self-Management Coaching Sessions to Improve Quality of Life in Pancreatic Cancer Survivors and Their Family Care Givers No drug interventions supportive_care Not Available not_yet_recruiting NCT02757391
CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal Tumors treatment 1 terminated NCT06396091
A Study of Zolbetuximab With Chemotherapy in Adults With Pancreatic Cancer treatment 1 recruiting NCT05642962
Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC) treatment 1 / 2 recruiting NCT03331562
A SU2C Catalyst® Trial of a PD1 Inhibitor With or Without a Vitamin D Analog for the Maintenance of Pancreatic Cancer treatment 2 completed NCT01954992
Glufosfamide Versus 5-FU in Second Line Metastatic Pancreatic Cancer treatment 3 recruiting NCT02227940
Ceritinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Locally Advanced or Metastatic Pancreatic Cancer treatment 1 completed NCT03943667
Gemcitabine and Paclitaxel vs Gemcitabine Alone After FOLFIRINOX Failure in Metastatic Pancreatic Ductal Adenocarcinoma treatment 3 completed NCT04229004
A Multi-center Trial to Evaluate Multiple Regimens in Metastatic Pancreatic Cancer treatment 3 active_not_recruiting NCT01204372
Trial Evaluating Combined Chemotherapy in Patients With Metastatic Pancreatic Adenocarcinoma treatment 2 completed NCT02436668
Study of Ibrutinib vs Placebo, in Combination With Nab-paclitaxel and Gemcitabine, in the First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma (RESOLVE) treatment 3 completed NCT03095781
Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal Cancer treatment 1 completed NCT01729481
Gemcitabine Plus Erlotinib in RASH-positive Patients With Metastatic Pancreatic Cancer treatment 2 unknown_status NCT02575508
Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer treatment 1 / 2 withdrawn NCT02677038
Olaparib in Treating Patients With Stage IV Pancreatic Cancer treatment 2 completed NCT02324543
Study of Gemcitabine/Taxotere/Xeloda (GTX) in Combination With Cisplatin and Irinotecan in Subjects With Metastatic Pancreatic Cancer treatment 1 / 2 completed NCT02671890
Disulfiram and Chemotherapy in Treating Patients With Refractory Solid Tumors or Metastatic Pancreatic Cancer treatment 1 active_not_recruiting NCT05102721
Trial of Immunotherapy With Avelumab and Pepinemab As Second Line For Patients With Metastatic Pancreatic Adenocarcinoma treatment 1 / 2 recruiting NCT04524702
Paricalcitol and Hydroxychloroquine in Combination With Gemcitabine and Nab-Paclitaxel for Advanced Pancreatic Cancer treatment 2 active_not_recruiting NCT03337087
Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer treatment 1 / 2 active_not_recruiting NCT01964287
First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma. treatment 1 / 2 completed NCT03910387
Telotristat Ethyl to Promote Weight Stability in Patients With Advanced Stage Pancreatic Cancer supportive_care 2 active_not_recruiting NCT02383433
Regorafenib Plus Gemcitabine in Metastatic Pancreatic Cancer treatment 2 terminated NCT06381154
Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer treatment 2 not_yet_recruiting NCT01360853
Gemcitabine and ON 01910.Na in Previously Untreated Metastatic Pancreatic Cancer treatment 3 completed NCT02562898
Ibrutinib Combined With Gemcitabine and Nab-Paclitaxel in Patients With Metastatic Pancreatic Cancer treatment 1 / 2 completed NCT01585805
Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer treatment 2 active_not_recruiting NCT05484011
A Maintenance Therapy Study of Odetiglucan With CDX-1140 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma treatment 1 terminated NCT01660971
Gemcitabine Hydrochloride, Dasatinib, and Erlotinib Hydrochloride in Treating Patients With Pancreatic Cancer That Is Metastatic or Cannot Be Removed by Surgery treatment 1 active_not_recruiting NCT02333188
Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancer No drug interventions treatment 1 completed NCT04548752
Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations No drug interventions treatment 2 recruiting NCT01233375
Study to Evaluate Efficacy of CO-1.01 as Second Line Therapy for Gemcitabine-Refractory Stage IV Pancreatic Adenocarcinoma No drug interventions treatment 2 completed NCT05078775
Medical Food for the Dietary Management of Advanced/Metastatic Pancreatic Cancer No drug interventions treatment Not Available recruiting NCT01562899
A Study of MEK162 and AMG 479 in Patients With Selected Solid Tumors No drug interventions treatment 1 / 2 terminated NCT02907099
Pembrolizumab and CXCR4 Antagonist BL-8040 in Treating Patients With Metastatic Pancreatic Cancer No drug interventions treatment 2 completed NCT05926206
Trial of Devimistat in Combination With Modified FOLFIRINOX in Patients With Metastatic Adenocarcinoma of the Pancreas No drug interventions treatment 1 / 2 withdrawn NCT06043713
Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Pancreatic, Colorectal and Non-Small Cell Lung Cancers With KRAS G12V Mutations No drug interventions treatment 1 recruiting NCT01415713
The Study of Metastatic Pancreatic Adenocarcinoma No drug interventions treatment 1 / 2 completed NCT03878524
Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial No drug interventions treatment 1 terminated NCT02567396
Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction No drug interventions treatment 1 withdrawn NCT06229496
Dose Escalation and Dose Expansion Study of GAS in Subjects With Metastatic Pancreatic Adenocarcinoma No drug interventions treatment 1 recruiting NCT03816163
A Study of Zolbetuximab (IMAB362) in Adults With Pancreatic Cancer No drug interventions treatment 2 active_not_recruiting NCT01124786
A Study Comparing CO-1.01 With Gemcitabine as First Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma (LEAP) No drug interventions treatment 2 completed NCT00998322
A Study of REOLYSIN® in Combination With Gemcitabine in Patients With Advanced Pancreatic Adenocarcinoma No drug interventions treatment 2 completed NCT01830322
Safety and Effectiveness Study of CPI-613 and/or Gemcitabine to Treat Metastatic Pancreatic Cancer No drug interventions treatment 2 withdrawn NCT03269526
BATs Treatment for Pancreatic Cancer, Phase Ib/II No drug interventions treatment 1 / 2 active_not_recruiting NCT04233866
Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread No drug interventions treatment 2 active_not_recruiting NCT02620865
BATS With in Combination With Low Dose IL-1 and GM-CSF for Advanced Pancreatic Cancer No drug interventions treatment 1 / 2 completed NCT03608631
iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation No drug interventions treatment 1 active_not_recruiting NCT05034627
Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer No drug interventions treatment 1 recruiting NCT04787991
Exploratory Platform Trial to Evaluate Immunotherapy Combinations With Chemotherapy for the Treatment of Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma No drug interventions treatment 1 active_not_recruiting NCT02194829
Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Gemcitabine Hydrochloride With or Without WEE1 Inhibitor AZD1775 in Treating Patients With Previously Untreated Pancreatic Cancer That Is Metastatic or Cannot Be Removed by Surgery No drug interventions treatment 1 / 2 completed NCT02045589
A Phase I Dose Escalation Study of Intratumoral VCN-01 Injections With Gemcitabine and Abraxane® in Patients With Advanced Pancreatic Cancer No drug interventions treatment 1 completed NCT05249101
A Study of Ivaltinostat Plus Capecitabine or Capecitabine in Metastatic Pancreatic Adenocarcinoma No drug interventions treatment 1 / 2 recruiting NCT01896869
FOLFIRINOX Followed by Ipilimumab With Pancreatic Tumor Vaccine in Treatment of Metastatic Pancreatic Cancer No drug interventions treatment 2 completed NCT02077881
Study of IDO Inhibitor in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Metastatic Pancreatic Cancer No drug interventions treatment 1 / 2 completed NCT02890355
FOLFIRI or Modified FOLFIRI and Veliparib as Second Line Therapy in Treating Patients With Metastatic Pancreatic Cancer No drug interventions treatment 2 active_not_recruiting NCT03214250
Safety and Efficacy of APX005M With Gemcitabine and Nab-Paclitaxel With or Without Nivolumab in Patients With Previously Untreated Metastatic Pancreatic Adenocarcinoma No drug interventions treatment 1 / 2 completed NCT02231723
A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Pancreatic Cancer No drug interventions treatment 1 completed