Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (DBCOND0064631)

Identifiers

Synonyms

Chronic Heart Failure With Reduced Systolic Function / Chronic Heart Failure With Reduced Ejection Fraction / Reduced ejection fraction co-occurrent and due to chronic heart failure (disorder)

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT02653482	Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure	Dapagliflozin	treatment	4	completed
NCT01876433	Beta 3 Agonist Treatment in Heart Failure	Mirabegron	treatment	2	completed
NCT03036124	Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure	Dapagliflozin	treatment	3	completed
NCT05728502	An Observational Study, Called VERI-China, to Learn More About How Well Vericiguat Works and How Safe it is in Real-world Setting in People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in China	Vericiguat	Not Available	Not Available	recruiting
NCT06486844	An Observational Study Called ROVER to Learn More About How Well Vericiguat Works in People Who Were Newly Treated With Vericiguat in Routine Medical Care in Germany	Vericiguat	Not Available	Not Available	recruiting
NCT06632483	An Observational Study to Learn More About How Safe Vericiguat is and How Well It Works in Indian People with Chronic Heart Failure with Reduced Ejection Fraction and Worsening Chronic Heart Failure Under Real World Conditions	Vericiguat	Not Available	Not Available	not_yet_recruiting
NCT05658458	A Study to Learn How Well the Drug Vericiguat Works and How Safe it is Under Real World Conditions in Indian Participants After Worsening of a Long-term Heart Condition in Which the Left Side of the Heart Does Not Pump Blood as Well as it Should (Chronic Heart Failure With Reduced Ejection Fraction)	Vericiguat	treatment	4	completed
NCT06148935	An Observational Study to Learn More About the Use of Vericiguat in Korean People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in Real-world Setting	Vericiguat	Not Available	Not Available	recruiting
NCT05974189	The VERIFY Study: An Observational Study Called VERIFY to Learn More About the Use of Vericiguat in People With Chronic Heart Failure With Reduced Ejection Fraction	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT05093933	A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035)	Vericiguat	treatment	3	active_not_recruiting
NCT02768298	Exercise Capacity Study of LCZ696 vs. Enalapril in Patients With Chronic Heart Failure and Reduced Ejection Fraction.	Enalapril Sacubitril	treatment	4	completed
NCT02900378	randOmized stUdy Using acceleromeTry to Compare Sacubitril/valsarTan and Enalapril in Patients With Heart Failure	Enalapril Sacubitril Valsartan	treatment	3	completed
NCT05553886	S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction	No drug interventions	treatment	3	recruiting
NCT04464525	Omecamtiv Mecarbil Post-trial Access Study	Omecamtiv Mecarbil	treatment	3	withdrawn
NCT02226120	Safety and Tolerability During Open-label Treatment With LCZ696 in Patients With CHF and Reduced Ejection Fraction	Sacubitril	treatment	3	completed
NCT06363110	An Observational Study to Learn More About Vericiguat Treatment Patterns and Its Safety in People With Chronic Heart Failure With Reduced Ejection Fraction in Routine Medical Care in the United States	Vericiguat	Not Available	Not Available	completed
NCT04983043	Efficacy and Safety of QiShen YiQi Dripping Pills in Chronic Heart Failure	No drug interventions	treatment	2	recruiting
NCT02861534	A Study of Vericiguat in Participants With Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-001)	Vericiguat	treatment	3	completed
NCT06195930	A Study to Learn How Safe Starting Vericiguat at a Dose of 5 Milligrams is in Participants With Chronic Heart Failure With Reduced Ejection Fraction	Vericiguat	treatment	2	completed
NCT04836182	A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx in Participants With Chronic Heart Failure With Reduced Ejection Fraction	No drug interventions	treatment	2	completed
NCT04840914	A Study of LY3461767 in Participants With Chronic Heart Failure With Reduced Ejection Fraction	No drug interventions	basic_science	1	completed