Supraventricular Arrhythmias (DBCOND0070681)

Identifiers

Synonyms

Supraventricular arrhythmia / Arrhythmia supraventricular / Supraventricular arrhythmias / Supraventricular arrhythmia (disorder) / Supraventricular arrhythmia NOS

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
ATP	For nutritional supplementation, also for treating dietary shortage or imbalance	Tyrosine-protein kinase ABL2target Phospholipid-transporting ATPase ABCA1target Acetyl-coenzyme A synthetase, cytoplasmictarget ALK tyrosine kinase receptortarget NEDD8-activating enzyme E1 regulatory subunittarget 5'-AMP-activated protein kinase catalytic subunit alpha-1target Serine/threonine-protein kinase A-Raftarget Activin receptor type-1-liketarget Long-chain-fatty-acid--CoA ligase 1target Cytosolic purine 5'-nucleotidasetarget ATPase GET3target ATP-binding cassette sub-family C member 9target RAC-alpha serine/threonine-protein kinasetarget Beta-adrenergic receptor kinase 1target Apoptotic protease-activating factor 1target Acetyl-coenzyme A synthetase 2-like, mitochondrialtarget Activin receptor type-1Btarget Activin receptor type-1target Bile salt export pumptarget Asparagine synthetase [glutamine-hydrolyzing]target Cyclin-dependent kinase 15target ADP/ATP translocase 1target ATP-binding cassette sub-family C member 8target Argininosuccinate synthasetarget Mitochondrial inner membrane m-AAA protease component AFG3L2target G protein-coupled receptor kinase 3target Anti-Muellerian hormone type-2 receptortarget Activated CDC42 kinase 1target Tyrosine-protein kinase ABL1target Adenylate cyclase type 1target ATP-dependent translocase ABCB1target ATP-binding cassette sub-family G member 1target ATP-binding cassette sub-family C member 2target Adenosine kinaseenzyme ATP-binding cassette sub-family C member 6target ATP-binding cassette sub-family C member 4target Multidrug resistance-associated protein 1target Cystic fibrosis transmembrane conductance regulatortarget Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget Casein kinase II subunit alphatarget Casein kinase II subunit betatarget P2Y purinoceptor 11target Serine/threonine-protein phosphatase 5target
Bisoprolol	A beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension.	Beta-1 adrenergic receptortarget Beta-2 adrenergic receptortarget Cytochrome P450 3A4enzyme ATP-dependent translocase ABCB1transporter
Hydroquinidine	A medication indicated in the maintenance of a normal sinus rhythm, as well as the treatment and prevention of abnormal rhythm.	No drug targets
Procainamide	A medication used to treat life threatening ventricular arrhythmias.	Sodium channel protein type 5 subunit alphatarget DNA (cytosine-5)-methyltransferase 1target Cytochrome P450 2D6enzyme Cholinesteraseenzyme Solute carrier family 22 member 2transporter Solute carrier family 22 member 1transporter Solute carrier family 22 member 3transporter Organic cation/carnitine transporter 2transporter Solute carrier family 22 member 4transporter Voltage-gated inwardly rectifying potassium channel KCNH2target Multidrug and toxin extrusion protein 1transporter Multidrug and toxin extrusion protein 2transporter
Propranolol	A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.	Beta-1 adrenergic receptortarget Beta-2 adrenergic receptortarget Beta-3 adrenergic receptortarget 5-hydroxytryptamine receptor 1Atarget 5-hydroxytryptamine receptor 1Btarget Cytochrome P450 1A2enzyme Cytochrome P450 2D6enzyme Alpha-1-acid glycoprotein 1carrier Cytochrome P450 2C19enzyme Cytochrome P450 3A4enzyme Cytochrome P450 3A5enzyme Cytochrome P450 3A7enzyme Solute carrier family 22 member 2transporter ATP-dependent translocase ABCB1transporter Cytochrome P450 1A1enzyme Amine oxidase [flavin-containing] Aenzyme Albumincarrier

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT02158728	Supraventricular Tachycardia Collection Study	No drug interventions	Not Available	Not Available	completed
NCT03665324	Atrial Function and Supraventricular Arrhythmia of the Veteran Athlete.	No drug interventions	Not Available	Not Available	completed
NCT05418036	Safety Assessment for Sotalol Protocol in Outpatient Unit	Sotalol	treatment	4	unknown_status
NCT05448716	Left Atrial Strain and Supraventricular Arrhythmia Burden in Cardiac Light Chain Amyloidosis Following Chemotherapy	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT06061120	Non-invasive Differentiation of Supraventricular Tachyarrhythmia	No drug interventions	Not Available	Not Available	recruiting
NCT04844801	Rate, Rhythm or Risk Control for New-onset Supraventricular Arrhythmia During Septic Shock: a Randomized Controlled Trial	No drug interventions	treatment	Not Available	unknown_status
NCT03029169	Propafenone Versus Amiodarone in Septic Shock	Amiodarone Propafenone	treatment	4	completed
NCT06082388	Atropine vs Isoprenaline in the Invasive Diagnosis of Arrhythmias	Atropine Isoprenaline	treatment	Not Available	not_yet_recruiting
NCT05643235	Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors	No drug interventions	other	Not Available	recruiting