Helminth Infection (DBCOND0082009)

Identifiers

Synonyms

Helminthic infection / Helminths Infection / Helminth Infections / Helminth infection / Helminthiasis, unspecified / Helminthic infection NOS / Infection caused by Cestoda and/or Trematoda and/or Phylum Nemata (disorder) / Helminth infection, unspecified / Helminthiasis

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Flubendazole	Flubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.	No drug targets
Niclosamide	An anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children.	DNAtarget Cytochrome P450 2C9enzyme Cytochrome P450 1A2enzyme
Oxantel	An antihelminthic indicated in the treatment of ascaris, trichocephaliasis, and oxyuriasis infections.	No drug targets
Pyrantel	An anthelmintic used to treat helminth infections.	G-protein coupled receptor 35target Cytochrome P450 4A11enzyme Muscarinic acetylcholine receptor M1target

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT03035760	Multiple Ascending Dose Study of Oxfendazole in Healthy Adult Volunteers	Oxfendazole	treatment	1	completed
NCT04137354	Iron and Vitamin A in School Children	No drug interventions	prevention	Not Available	completed
NCT06560853	Evaluation of a Comprehensive School Health Programme in Zambia	No drug interventions	health_services_research	Not Available	active_not_recruiting
NCT03441893	Role of Intestinal Protozoa and Helminths in the Course of Ulcerative Colitis	Mesalazine Nitazoxanide	treatment	1 / 2	active_not_recruiting
NCT03036059	Twice Yearly Treatment for the Control of LF	Albendazole Ivermectin	treatment	4	completed
NCT03598842	Tuberculosis - Learning the Impact of Nutrition	Albendazole Ivermectin Metronidazole	basic_science	Not Available	active_not_recruiting
NCT04227925	The Longevity of Trichuris Trichiura Colonization	No drug interventions	Not Available	Not Available	completed
NCT04642755	Comorbidities and Coinfections in Latent TB	No drug interventions	Not Available	Not Available	recruiting
NCT03032042	Intestinal Microbiome Post-Azythromycin/Albendazole Treatment	Albendazole Azithromycin	diagnostic	4	withdrawn
NCT05185778	Parasitism & COVID19 Vaccines: New Challenge.	No drug interventions	Not Available	Not Available	not_yet_recruiting
NCT04326868	Human Soil Transmitted Helminths (STH) Resistance to Benzimidazole in School Aged Children Living in Gabon	Albendazole Benzimidazole Mebendazole Pyrantel	treatment	4	completed
NCT04526613	The Influence of Malnutrition, Diabetes Mellitus, and Helminth Infections on Biosignatures in Latent Tuberculosis in a South Indian Population	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT02034162	A Study to Assess the Efficacy and Safety of Mebendazole for the Treatment of Helminth Infections in Pediatric Participants	Mebendazole	treatment	3	completed