Crotamiton is a topical scabicidal and antipruritic agent used for scabies eradication and for the relief of pruritus. It is a colorless to slightly yellowish oil, having a faint amine-like odor.
- Mechanism
- Curator reviewed
Crotamiton is an antiparasitic that is toxic to the scabies mite. Crotamiton also relieves itching by producing what is called a counter-irritation. As crotamiton evaporates from the skin, it produces a cooling effect. This cooling effect helps to divert your body's attention away from the itching.
- Primary indication
- For eradication of scabies (Sarcoptes scabiei) and for symptomatic treatment of pruritic skin.Curator reviewed · 2 structured indications
- Formula / weight
- C13H17NO · 203.2802 g/mol (avg)
- First approval
- Canada, 2001 · United States, 2008
- Brand names
Resolves to
Clinical / RWD
Structure
InChIKey
DNTGGZPQPQTDQF-XBXARRHUSA-NSMILESCCN(C(=O)C=CC)C1=CC=CC=C1CTargets
What you can answer from here — as of August 31, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Crotamiton, and which of those have an active Phase 3 trial?
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