Dexbrompheniramine is an antihistamine used to treat allergy symptoms including upper respiratory tract symptoms. Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions, such as hay fever or urticaria.
- Mechanism
- Curator reviewed
Dexbrompheniramine competitively binds to the histamine H1-receptor. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine.
- Primary indication
- For treatment and relief of symptoms of allergies, hay fever, and coldsCurator reviewed · 2 structured indications
- Formula / weight
- C16H19BrN2 · 319.239 g/mol (avg)
- First approval
- Canada, 2001 · United States, 2018
- Also known as
- d-brompheniramine · Desbrofeniramina
- Brand names
Resolves to
ZDIGNSYAACHWNL-HNNXBMFYSA-NSMILESCN(C)CC[C@@H](C1=CC=C(Br)C=C1)C1=CC=CC=N1What you can answer from here — as of September 23, 2026
Which drugs share a target with Dexbrompheniramine, and which of those have an active Phase 3 trial?
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