Ethinamate is a short-acting sedative-hypnotic medication used to treat insomnia. Like many such similar medications, the regular use of ethinamate can result in the development of drug tolerance in a... Nevertheless, the medication itself is generally no longer effective after using it for greater than 7 days.
- Mechanism
- Curator reviewed
The mechanism of action is not known. However, studies have shown that ethinamate inhibits carbonic anhydrases I and II (J Biol Chem. 1992 Dec 15;267(35):25044-50). This inhibition by ethinamate is not sufficiently strong, however, to implicate carbonic anhydrases I and II in the mechanism of action.
- Primary indication
- Used for the short-term treatment of insomnia, however, it generally has been replaced by other sedative-hypnotic agents.Curator reviewed
- Formula / weight
- C9H13NO2 · 167.205 g/mol (avg)
- Code names
- USAF EL-42
Resolves to
GXRZIMHKGDIBEW-UHFFFAOYSA-NSMILESNC(=O)OC1(CCCCC1)C#CWhat you can answer from here — as of September 16, 2026
Which drugs share a target with Ethinamate, and which of those have an active Phase 3 trial?
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