3-Methylthiofentanyl

DB01439ExperimentalIllicitSmall molecule

3-Methyl-thiofentanyl is a fentanyl analog and an opioid analgesic that works by inducing central nervous system (CNS) depression.

Mechanism: 3-Methylthiofentanyl binds to the mu, delta, and kappa opioid receptors. These ultimately lead to decreased pain sensation as well as a number of side effects, such as euphoria, sedation, depressed breathing.
Curator reviewed
Formula / weight: C₂₁H₂₈N₂OS · 356.525 g/mol (avg)
Also known as: 3-Methyl-thiofentanyl

Resolves to

Compound

Structure

InChIKeySRARDYUHGVMEQI-UHFFFAOYSA-NSMILESCCC(=O)N(C1CCN(CCC2=CC=CS2)CC1C)C1=CC=CC=C1

Targets

What you can answer from here — as of September 20, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

17+ReferencesStructured and connected to the statements they support

Which drugs share a target with 3-Methylthiofentanyl, and which of those have an active Phase 3 trial?

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