DB01686ExperimentalSmall molecule
Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which... ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health.
- Mechanism
- Curator reviewed
Pharmacologically active on Nitric oxide synthase, inducible and Nitric oxide synthase 3
- Formula / weight
- C8H18N4O2 · 202.2541 g/mol (avg)
- Also known as
- ADMA · Asymmetric dimethylarginine · dimethyl-L-arginine · L-NG,NG-dimethylarginine · N(G)-Dimethylarginine
- Code names
- Lopac-D-4268
Resolves to
Structure
InChIKey
YDGMGEXADBMOMJ-LURJTMIESA-NSMILESN[C@@H](CCC\N=C(/N)N(C)C)C(O)=OTargets
What you can answer from here — as of September 16, 2026
2Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with N,N-dimethylarginine, and which of those have an active Phase 3 trial?
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