Furo[2,3d]Pyrimidine Antifolate

DB02026ExperimentalSmall molecule

Furo[2,3d]Pyrimidine Antifolate: Overview.

Chemical structure of Furo[2,3d]Pyrimidine Antifolate
Formula / weight
C20H22N6O6 · 442.4253 g/mol (avg)

Resolves to

Compound
UNIIVBP3BN3U2VChEMBLCHEMBL104829PubChem158376
Structure
InChIKeyWXINNGCGSCFUCR-ZDUSSCGKSA-NSMILES[H][C@@](CCC(O)=O)(NC(=O)C1=CC=C(C=C1)N(C)CC1=COC2=NC(N)=NC(N)=C12)C(O)=O
Targets
Q9HBH1PDFP16184Dihydrofolate reductase

What you can answer from here — as of August 31, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Furo[2,3d]Pyrimidine Antifolate, and which of those have an active Phase 3 trial?

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