Peptide deformylase, mitochondrial

BE0002201ProteinHumansPDF

Removes the formyl group from the N-terminal Met of newly synthesized proteins. It is acted on by 27 drugs in DrugBank.

Gene name
PDF
UniProtKB entry
Q9HBH1Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
243 residues · 27,013 Da
Also known as
3.5.1.88 · PDF1A · Polypeptide deformylase

Resolves to

Protein
UniProtQ9HBH1UniProt nameDEFM_HUMAN
Gene
HGNCHGNC:30012NCBI Gene64146GenBank11320944GeneCardsPDF
Pharmacology
KEGGhsa:64146
Structure
PDB3G5KPDB3G5P
Drugs

What you can answer from here — as of September 07, 2019

27DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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37+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Peptide deformylase, mitochondrial, how selective are they, and which programs against it are still in active trials?

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