Amediplase

DB06679ExperimentalProtein Based Therapies

Amediplase is a recombinant chimeric plasminogen activator, consisting of the kringle 2 domain from the A-chain of tissue plasminogen activator (t-PA) and the carboxy terminal region of pro-urokinase. [MeSH].

Mechanism
Curator reviewed
Primary indication
Investigated for use/treatment in myocardial infarction and thrombosis.Curator reviewed

Resolves to

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
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706Drug interactionsStructured to mechanism, not free text
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5+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Amediplase, and which of those have an active Phase 3 trial?

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