Plasminogen

BE0000211ProteinHumansPLG

Protease which primary function is to degrade fibrin, the main component of blood clots (PubMed:6094526, PubMed:6919539). It is acted on by 25 drugs in DrugBank.

Gene name: PLG
UniProtKB entry: P00747Swiss-Prot
Cellular location: Secreted
Residues / weight: 810 residues · 90,568 Da

What you can answer from here — as of September 07, 2019

25DrugsApproved to experimental, with action, bond type and pharmacological action

4Clinical trialsTrials of drugs acting on it, by phase and status

12GO termsFunction, process and component, as structured annotations

3Pfam domainsDomain architecture mapped to Pfam families and clans

143+ReferencesStructured and connected to the statements they support

Which approved drugs act on Plasminogen, how selective are they, and which programs against it are still in active trials?

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