PLX-4720

DB06999ExperimentalSmall molecule

PLX-4720: Overview.

Mechanism: Pharmacologically active on Serine/threonine-protein kinase B-raf
Curator reviewed
Formula / weight: C₁₇H₁₄ClF₂N₃O₃S · 413.826 g/mol (avg)
Also known as: N-[3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide
Code names: PLX-4720

Resolves to

Compound

Structure

InChIKeyYZDJQTHVDDOVHR-UHFFFAOYSA-NSMILESCCCS(=O)(=O)NC1=CC=C(F)C(C(=O)C2=CNC3=C2C=C(Cl)C=N3)=C1F

Targets

What you can answer from here — as of January 29, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

11+ReferencesStructured and connected to the statements they support

Which drugs share a target with PLX-4720, and which of those have an active Phase 3 trial?

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