AS-8112

DB09207ExperimentalSmall molecule

AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5-HT3. It has been shown to exert... It has been shown to exert potent antiemetic effects in animal studies and has been investigated for potential medical use.

Formula / weight: C₁₇H₂₇BrN₄O₂ · 399.333 g/mol (avg)
Code names: AS-8112

Resolves to

Compound

PubChem10993014

Structure

InChIKeyDALSFUWTAOKVTF-GFCCVEGCSA-NSMILES[H]N(C)C1=C(Br)C=C(C(=O)N([H])[C@@H]2CN(C)CCN(CC)C2)C(OC)=C1

Targets

P14416DRD2P35462DRD3Q9UE695HT3 serotonin receptor

What you can answer from here — as of April 02, 2025

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

26Drug interactionsStructured to mechanism, not free text

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with AS-8112, and which of those have an active Phase 3 trial?

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