Lersivirine

DB11649InvestigationalSmall molecule

Lersivirine has been used in trials studying the treatment of HIV-1.

Mechanism: Pharmacologically active on Reverse transcriptase/RNaseH
Curator reviewed
Formula / weight: C₁₇H₁₈N₄O₂ · 310.3504 g/mol (avg)
Code names: UK-453,061

Resolves to

Compound

Structure

InChIKeyMCPUZZJBAHRIPO-UHFFFAOYSA-NSMILESCCC1=NN(CCO)C(CC)=C1OC1=CC(=CC(=C1)C#N)C#N

Targets

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Lersivirine, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.