Reverse transcriptase/RNaseH

BE0004136ProteinHuman immunodeficiency virus 1pol

Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) is a protein target in DrugBank. It is acted on by 41 drugs in DrugBank.

Gene name
pol
UniProtKB entry
Q72547TrEMBL
Cellular location
Cytoplasmic
Residues / weight
566 residues · 65,224 Da

Resolves to

Protein
UniProtQ72547UniProt nameQ72547_HV1
Gene
GenBank896047
Structure
PDB2JLEPDB3HYFPDB3QIN
Drugs

What you can answer from here — as of September 07, 2019

41DrugsApproved to experimental, with action, bond type and pharmacological action
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18Clinical trialsTrials of drugs acting on it, by phase and status
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5GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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126+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Reverse transcriptase/RNaseH, how selective are they, and which programs against it are still in active trials?

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