Derenofylline

DB12446InvestigationalSmall molecule

Derenofylline has been used in trials studying the treatment of Congestive Heart Failure and Acute Decompensated Heart Failure; Renal Dysfunction.

Mechanism: Pharmacologically active on Adenosine receptor A1
Curator reviewed
Formula / weight: C₁₈H₂₀N₄O · 308.385 g/mol (avg)
Code names: SLV-320

Resolves to

Compound

Structure

InChIKeyRBZNJGHIKXAKQE-HDJSIYSDSA-NSMILESO[C@H]1CC[C@@H](CC1)NC1=C2C=CNC2=NC(=N1)C1=CC=CC=C1

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Derenofylline, and which of those have an active Phase 3 trial?

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