Nadifloxacin

DB12447InvestigationalSmall molecule

Nadifloxacin is a topical fluoroquinolone used in the treatment of acne and topical bacterial skin infections. An antibiotic applied to the skin to treat acne and certain skin infections.

Mechanism: The exact mechanism of action of nadifloxacin has not been fully elucidated.
Curator reviewed
Formula / weight: C₁₉H₂₁FN₂O₄ · 360.385 g/mol (avg)

Resolves to

Compound

UNII6CL9Y5YZEQCAS124858-35-1ChEMBLCHEMBL363449ChEBI31889PubChem4410

Clinical / RWD

ATCD10AF05

Structure

InChIKeyJYJTVFIEFKZWCJ-UHFFFAOYSA-NSMILESCC1CCC2=C3N1C=C(C(O)=O)C(=O)C3=CC(F)=C2N1CCC(O)CC1

Targets

P0AES4gyrAP0C1U9parC

What you can answer from here — as of September 13, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4Drug interactionsStructured to mechanism, not free text

2Clinical trialsPhase, status and sponsor resolved per trial

2Structured indicationsCondition, population, route and combination as fields, not prose

1ContraindicationEach with its own population and attribute set

11Marketed productsAcross 4 countries and 7 labellers

1ATC codeIncluding every combination product, plus 13 drug categories

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Nadifloxacin, and which of those have an active Phase 3 trial?

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