DNA topoisomerase 4 subunit A

BE0008383ProteinStaphylococcus aureusparC

Topoisomerase IV is essential for chromosome segregation. It is acted on by 6 drugs in DrugBank.

Gene name
parC
UniProtKB entry
P0C1U9Swiss-Prot
Cellular location
Cell membrane
Residues / weight
800 residues · 91,040 Da
Also known as
5.6.2.2 · 5.99.1.3 · grlA · Topoisomerase IV subunit A

Resolves to

Protein
UniProtP0C1U9UniProt namePARC_STAAU
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on DNA topoisomerase 4 subunit A, how selective are they, and which programs against it are still in active trials?

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