Sofinicline

DB12527InvestigationalSmall molecule

Sofinicline has been used in trials studying the treatment of ADHD, Neuralgia, Diabetic, Diabetic Neuropathies, Diabetic Polyneuropathy, and Diabetic Neuropathic Pain, among others.

Chemical structure of Sofinicline
Formula / weight
C10H11Cl2N3 · 244.12 g/mol (avg)
Code names
A-422894.0 · ABT-894

Resolves to

Compound
UNIISQC232V4YYCAS799279-80-4ChEMBLCHEMBL238465PubChem10131048
Structure
InChIKeyMBQYQLWSBRANKQ-IMTBSYHQSA-NSMILESClC1=C(Cl)N=CC(=C1)N1C[C@@H]2CN[C@@H]2C1
Targets
P17787CHRNB2P43681CHRNA4

What you can answer from here — as of January 29, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action
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3Clinical trialsPhase, status and sponsor resolved per trial
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Sofinicline, and which of those have an active Phase 3 trial?

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