Endothelin receptor type B

BE0000043ProteinHumansEDNRB

Non-specific receptor for endothelin 1, 2, and 3. It is acted on by 16 drugs in DrugBank.

Gene name
EDNRB
UniProtKB entry
P24530Swiss-Prot
Cellular location
Cell membrane
Residues / weight
442 residues · 49,643 Da
Also known as
Endothelin receptor non-selective type · ET-B · ET-BR · ETRB

Resolves to

Protein
UniProtP24530UniProt nameEDNRB_HUMAN
Gene
HGNCHGNC:3180NCBI Gene1910GenBank182276GeneCardsEDNRB
Pharmacology
IUPHAR/GtoPdb220KEGGhsa:1910
Structure
PDB5GLHPDB5GLIPDB5X93
Drugs

What you can answer from here — as of September 03, 2024

16DrugsApproved to experimental, with action, bond type and pharmacological action
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31GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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82+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Endothelin receptor type B, how selective are they, and which programs against it are still in active trials?

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