This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Meptazinol
- DrugBank Accession Number
- DB13478
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Meptazinol (DB13478)
- Weight
- Average: 233.355
Monoisotopic: 233.177964365 - Chemical Formula
- C15H23NO
- Synonyms
- Meptazinol
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your software1,2-Benzodiazepine The risk or severity of adverse effects can be increased when Meptazinol is combined with 1,2-Benzodiazepine. Acetazolamide The risk or severity of CNS depression can be increased when Acetazolamide is combined with Meptazinol. Acetophenazine The risk or severity of hypotension and CNS depression can be increased when Acetophenazine is combined with Meptazinol. Aclidinium The risk or severity of adverse effects can be increased when Aclidinium is combined with Meptazinol. Agomelatine The risk or severity of CNS depression can be increased when Agomelatine is combined with Meptazinol. - Food Interactions
- Not Available
Categories
- ATC Codes
- N02AX05 — Meptazinol
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as azepanes. These are organic compounds containing a saturated seven member heterocycle, with one nitrogen atom.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Azepanes
- Sub Class
- Not Available
- Direct Parent
- Azepanes
- Alternative Parents
- Aralkylamines / 1-hydroxy-4-unsubstituted benzenoids / 1-hydroxy-2-unsubstituted benzenoids / Benzene and substituted derivatives / Trialkylamines / Azacyclic compounds / Organopnictogen compounds / Organooxygen compounds / Hydrocarbon derivatives
- Substituents
- 1-hydroxy-2-unsubstituted benzenoid / 1-hydroxy-4-unsubstituted benzenoid / Amine / Aralkylamine / Aromatic heteromonocyclic compound / Azacycle / Azepane / Benzenoid / Hydrocarbon derivative / Monocyclic benzene moiety
- Molecular Framework
- Aromatic heteromonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 18Y7S5JKZD
- CAS number
- 54340-58-8
- InChI Key
- JLICHNCFTLFZJN-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H23NO/c1-3-15(9-4-5-10-16(2)12-15)13-7-6-8-14(17)11-13/h6-8,11,17H,3-5,9-10,12H2,1-2H3
- IUPAC Name
- 3-(3-ethyl-1-methylazepan-3-yl)phenol
- SMILES
- CCC1(CCCCN(C)C1)C1=CC(O)=CC=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 37469
- BindingDB
- 50373116
- 6761
- ChEBI
- 91484
- ChEMBL
- CHEMBL314437
- Wikipedia
- Meptazinol
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.354 mg/mL ALOGPS logP 3.75 ALOGPS logP 3.07 Chemaxon logS -2.8 ALOGPS pKa (Strongest Acidic) 10.23 Chemaxon pKa (Strongest Basic) 9.16 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 23.47 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 72.28 m3·mol-1 Chemaxon Polarizability 27.89 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 155.32199 predictedDeepCCS 1.0 (2019) [M+H]+ 157.67998 predictedDeepCCS 1.0 (2019) [M+Na]+ 163.77313 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:42 / Updated at February 21, 2021 18:54