This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Nitrate
- DrugBank Accession Number
- DB14049
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental, Investigational
- Structure
Structure for Nitrate (DB14049)
- Weight
- Average: 62.0049
Monoisotopic: 61.987817871 - Chemical Formula
- NO3
- Synonyms
- Nitrate ion
- Nitrates
- External IDs
- N511
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAmiodarone Amiodarone may increase the vasodilatory activities of Nitrate. Amlodipine Amlodipine may increase the vasodilatory activities of Nitrate. Avanafil Avanafil may increase the hypotensive activities of Nitrate. Bepridil Bepridil may increase the vasodilatory activities of Nitrate. Carvedilol Carvedilol may increase the vasodilatory activities of Nitrate. Cinnarizine Cinnarizine may increase the vasodilatory activities of Nitrate. Clevidipine Clevidipine may increase the vasodilatory activities of Nitrate. Cyclandelate Cyclandelate may increase the vasodilatory activities of Nitrate. Diltiazem Diltiazem may increase the vasodilatory activities of Nitrate. Dipyridamole The risk or severity of hypotension can be increased when Dipyridamole is combined with Nitrate. 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of inorganic compounds known as non-metal nitrates. These are inorganic non-metallic compounds containing a nitrate as its largest oxoanion.
- Kingdom
- Inorganic compounds
- Super Class
- Homogeneous non-metal compounds
- Class
- Non-metal oxoanionic compounds
- Sub Class
- Non-metal nitrates
- Direct Parent
- Non-metal nitrates
- Alternative Parents
- Inorganic oxides
- Substituents
- Inorganic oxide / Non-metal nitrate
- Molecular Framework
- Not Available
- External Descriptors
- monovalent inorganic anion, nitrogen oxoanion, reactive nitrogen species (CHEBI:17632) / an anion (NITRATE)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- T93E9Y2844
- CAS number
- 14797-55-8
- InChI Key
- NHNBFGGVMKEFGY-UHFFFAOYSA-N
- InChI
- InChI=1S/NO3/c2-1(3)4/q-1
- IUPAC Name
- nitrate
- SMILES
- [O-]N(=O)=O
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0002878
- ChemSpider
- 918
- BindingDB
- 26988
- 1546271
- ChEBI
- 17632
- ChEMBL
- CHEMBL186200
- PDBe Ligand
- NO3
- Wikipedia
- Nitrate
- PDB Entries
- 1a4c / 1azr / 1bg0 / 1can / 1ch8 / 1cib / 1dkk / 1e5y / 1e5z / 1e67 … show 875 more
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Completed Treatment Myocardial Ischemia / Quality of Life (QOL) / Stable Angina (SA) 1 4 Recruiting Prevention Length of Hospital Stay 1 4 Recruiting Treatment Myocardial Infarction With Non-obstructive Coronary Arteries 1 4 Unknown Status Treatment Coronary Artery Disease (CAD) 1 3 Completed Prevention Osteoporosis 1 3 Completed Prevention Pancreatitis 1 3 Completed Treatment Diabetic Foot Ulcers (DFUs) 1 3 Completed Treatment Hypotensive Syncope 1 2 Completed Basic Science Postmenopausal 2 2 Completed Treatment Vulvovaginal Candidiasis 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 0.84 Chemaxon pKa (Strongest Basic) -9.9 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 66.2 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 8.35 m3·mol-1 Chemaxon Polarizability 3.28 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key MS/MS Spectrum - Quattro_QQQ 10V, Negative LC-MS/MS splash10-03di-9000000000-62b6946f773f2794ce2b MS/MS Spectrum - Quattro_QQQ 25V, Negative LC-MS/MS splash10-03dj-9000000000-b705d64f017cd9970bcb MS/MS Spectrum - Quattro_QQQ 40V, Negative LC-MS/MS splash10-03di-9000000000-a03d650125e7c3c9631a Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created at June 06, 2018 15:27 / Updated at June 12, 2020 16:53