Methionine sulfoximine

DB14103InvestigationalSmall molecule

Methionine sulfoximine: Overview.

Mechanism: Pharmacologically active on Glutamate--cysteine ligase catalytic subunit and Glutamine synthetase
Curator reviewed
Formula / weight: C₅H₁₂N₂O₃S · 180.22 g/mol (avg)
Also known as: BUTANOIC ACID, 2-AMINO-4-(S-METHYLSULFONIMIDOYL)-, (2S)- · L-methionine sulfoximine · METHIONINE-DL-SULFOXIMINE · METHIONINE-DL-SULFOXIMINE, L-

Resolves to

Compound

Clinical / RWD

Structure

InChIKeySXTAYKAGBXMACB-DPVSGNNYSA-NSMILESCS(=N)(=O)CC[C@H](N)C(O)=O

Targets

What you can answer from here — as of July 10, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2Marketed productsAcross 1 country and 1 labeller

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Methionine sulfoximine, and which of those have an active Phase 3 trial?

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