Ephedrine tannateProduct ingredient for Ephedrine

Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine.⁵ Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine from storage vesicles.^4,8 Ephedrine is used for its vasoconstrictive, positive chronotropic, and positive inotropic effects.⁸ Ephedrine and phenylephrine are still used to treat hypotension, but their use in other indications has decreased due to the development of more selective adrenergic agonists.^6,7,9 Ephedrine was granted a type 7 FDA Approval on 29 April 2016.⁹