Fosinoprilat

DB14207ExperimentalSmall moleculeAngiotensin-Converting Enzyme Inhibitors

Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.

Mechanism: Pharmacologically active on Angiotensin-converting enzyme
Curator reviewed
Formula / weight: C₂₃H₃₄NO₅P · 435.4935 g/mol (avg)
Also known as: Fosinopril diacid · Fosinoprilic acid

Resolves to

Compound

UNIIS312EY6ZT8CAS95399-71-6ChEMBLCHEMBL581ChEBI116962KEGGD03772

Clinical / RWD

RxNorm1546393

Structure

InChIKeyWOIWWYDXDVSWAZ-RTWAWAEBSA-NSMILES[H][C@]1(C[C@H](N(C1)C(=O)CP(O)(=O)CCCCC1=CC=CC=C1)C(O)=O)C1CCCCC1

Targets

P12821ACEP09960LTA4H

What you can answer from here — as of July 07, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

897Drug interactionsStructured to mechanism, not free text

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Fosinoprilat, and which of those have an active Phase 3 trial?

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