This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Centella asiatica
- DrugBank Accession Number
- DB14256
- Background
Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
- Type
- Biotech
- Groups
- Approved, Experimental, Investigational
- Synonyms
- Asiatic Pennywort Whole
- Bacopa Monniera Whole Extract
- Bacopa Whole
- Brahmi Whole
- Centella Asiatica Extract
- Coastal Water-hyssop Whole
- Gotu Kola
- Gotu Kola Whole
- Herba Centellae
- Hydrocotyle
- Hydrocotyle Asiatica
- Indian Pennywort Whole
- Ji Xue Cao Whole
- Jixuecao Whole
- Luo De Da Whole
- Ma Ti Cao Whole
- Mandukaparni Whole
- Sheep-rot Whole
- Spadeleaf Whole
- Thankuni Whole
- Water Hyssop Whole
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Treatment of Burns first degree •••••••••••• •••••••• Management of Capillary fragility ••• ••• ••••• •••••• Used in combination for symptomatic treatment of Itching Combination Product in combination with: Neomycin (DB00994) ••• ••• •••••••• Treatment of Radiation burn •••••••••••• •••••••• Treatment of Second degree burns •••••••••••• •••••••• - Associated Therapies
- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcetazolamide The therapeutic efficacy of Acetazolamide can be decreased when used in combination with Centella asiatica. Amifampridine The risk or severity of seizure can be increased when Centella asiatica is combined with Amifampridine. Amobarbital The therapeutic efficacy of Amobarbital can be decreased when used in combination with Centella asiatica. Brexanolone The therapeutic efficacy of Brexanolone can be decreased when used in combination with Centella asiatica. Brivaracetam The therapeutic efficacy of Brivaracetam can be decreased when used in combination with Centella asiatica. - Food Interactions
- Take with food.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Centellaca A Clear Relaxing Toner Liquid 55.45 mg/100mL Topical Wow Ventures 2015-05-01 2017-07-15 US 
Cothilyne- Asp-tct 89.5 Spray; Tincture 89.5 % Topical Haemacure Corporation 1995-12-31 1999-10-05 Canada 
Cream Cream 6 mg/30mg Cutaneous Shantou Youjia E-Commerce Co.,Ltd. 2024-02-01 2024-12-31 US Elcure Curekin Shampoo 3000 mg/300mL Topical Elcure Co., Ltd. 2013-07-18 2017-04-20 US eves centella 20 V1 Volume Ampoule Liquid 1 g/100mL Topical eveskorea 2022-11-22 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ACTS38 BoswelliaGel Centella asiatica (0.01 g/100mL) + Sodium hyaluronate (0.01 g/100mL) + Indian frankincense (1.2 g/100mL) + N-Acetylglucosamine (0.1 g/100mL) Gel Topical A-Lot Biologics Inc 2022-09-07 Not applicable US ACTS38 BoswelliaGel (100ml) Centella asiatica (0.01 g/100mL) + Sodium hyaluronate (0.01 g/100mL) + Indian frankincense (1.2 g/100mL) + N-Acetylglucosamine (0.1 g/100mL) Gel Topical A-Lot Biologics Inc 2022-10-23 Not applicable US Ato Standard Intensivecream Centella asiatica (0.003 g/100g) + Ceramide NP (0.0006 g/100g) + Macadamia oil (2 g/100g) + Panthenol (0.75 g/100g) Cream Topical TIMEBIO Co., Ltd 2020-12-03 Not applicable US Ato Standard Premium Mildcream Centella asiatica (0.005 g/100g) + Ceramide NP (0.0018 g/100g) + Shea butter (3 g/100g) Cream Topical TIMEBIO Co., Ltd 2021-02-01 Not applicable US Centella 65 Green Tea Pack Centella asiatica (65 g/100g) + Green tea leaf (1 g/100g) Cream Topical Ami Cosmetic Co.,Ltd. 2016-02-23 2019-03-28 US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ACTS38 BoswelliaGel Centella asiatica (0.01 g/100mL) + Sodium hyaluronate (0.01 g/100mL) + Indian frankincense (1.2 g/100mL) + N-Acetylglucosamine (0.1 g/100mL) Gel Topical A-Lot Biologics Inc 2022-09-07 Not applicable US ACTS38 BoswelliaGel (100ml) Centella asiatica (0.01 g/100mL) + Sodium hyaluronate (0.01 g/100mL) + Indian frankincense (1.2 g/100mL) + N-Acetylglucosamine (0.1 g/100mL) Gel Topical A-Lot Biologics Inc 2022-10-23 Not applicable US Ato Standard Intensivecream Centella asiatica (0.003 g/100g) + Ceramide NP (0.0006 g/100g) + Macadamia oil (2 g/100g) + Panthenol (0.75 g/100g) Cream Topical TIMEBIO Co., Ltd 2020-12-03 Not applicable US Ato Standard Premium Mildcream Centella asiatica (0.005 g/100g) + Ceramide NP (0.0018 g/100g) + Shea butter (3 g/100g) Cream Topical TIMEBIO Co., Ltd 2021-02-01 Not applicable US Centella 65 Green Tea Pack Centella asiatica (65 g/100g) + Green tea leaf (1 g/100g) Cream Topical Ami Cosmetic Co.,Ltd. 2016-02-23 2019-03-28 US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 4YS74Q4G4J
- CAS number
- Not Available
References
- General References
- Not Available
- External Links
- 1807125
- Wikipedia
- Centella_asiatica
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Unknown Status Treatment Dry Skin / Type 2 Diabetes Mellitus 1 2 Completed Treatment Diabetic Neuropathies 1 1 Completed Treatment Gingival Diseases 1 1 Recruiting Treatment Alzheimer's Disease (AD) / Mild Cognitive Impairment (MCI) 1 0 Active Not Recruiting Screening Elderly / Healthy Volunteers (HV) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Gel Topical Insert Vaginal Liquid Topical 55.45 mg/100mL Tablet Oral Spray; tincture Topical 89.5 % Cream Cutaneous 6 mg/30mg Patch Cutaneous Patch Topical Shampoo Topical 3000 mg/300mL Liquid Topical 1 g/100mL Gel Vaginal Gel Topical 0.01 g/100mL Cream Topical Liquid Cutaneous Ointment Topical Ointment 1 % Poultice Cutaneous Oil Cutaneous Gel Vaginal 15 g/100mL Cream Cutaneous Lotion Topical Cream Topical 0.3 mg/31 Liquid Topical 0.30 g/100mL Liquid Topical Liquid Topical 0.01 g/100g Cream Topical 0.001 g/100g Gel Topical 0.1 g/100mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at July 05, 2018 17:13 / Updated at June 22, 2021 18:16