Modimelanotide

DB15314InvestigationalSmall molecule

Modimelanotide is under investigation in clinical trial NCT01897519 (A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High...

Mechanism: Pharmacologically active on Melanocyte-stimulating hormone receptor and Melanocortin receptor 3
Curator reviewed
Formula / weight: C₁₁₃H₁₈₁N₃₃O₂₅S · 2433.96 g/mol (avg)
Code names: ABT-719

Resolves to

Compound

UNII96C1EBE9CGCAS926277-68-1

Structure

InChIKeyWHRVKPBBRZHWTN-ZHHKRVSMSA-NSMILES

CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(N)=O

Targets

Q01726MC1RP41968MC3R

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Modimelanotide, and which of those have an active Phase 3 trial?

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