AGG-523

DB15460InvestigationalSmall molecule

AGG-523 is under investigation in clinical trial NCT00380900 (Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy subjects and in subjects with osteoarthritis).

Formula / weight: C₂₈H₂₉FN₂O₄ · 476.548 g/mol (avg)
Code names: AGG-523

Resolves to

Compound

UNIIWO23I2827QCAS920289-29-8

Structure

InChIKeyJWQMTWCFNZSLNR-DEOSSOPVSA-NSMILESCC(C)(CC1=CC=C(F)C=C1)NC(=O)[C@H](CCC(O)=O)NC(=O)C1=CC=C(C=C1)C1=CC=CC=C1

Targets

Q9UNA0ADAMTS5

What you can answer from here — as of April 23, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with AGG-523, and which of those have an active Phase 3 trial?

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