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Ferric maltol is a complexed iron supplement used to treat iron deficiency in adults and pediatrics. Ferric maltol is an iron(III) atom complexed with 3 maltol molecules to increase the bioavailability compared to iron(II), without depositing it in the duodenum as insoluble ferric hydroxide and phosphate.
- Mechanism
- Curator reviewed · 3 references
Ferric maltol dissociates as the iron atom is donated to unknown iron uptake mechanisms, possibly beta 3 integrin or divalent metal transporter 1, in the ileum and duodenum. Once the iron is in circulation, it then associates with transferrin and ferritin.
- Primary indication
- Ferric maltol is indicated for the treatment of iron deficiency in adults and pediatric patients aged 10 years and older.Curator reviewed · 1 structured indication
- Formula / weight
- C18H15FeO9 · 431.154 g/mol (avg)
- First approval
- Canada, 2024 · United States, 2021 · European Union, 2020
- Also known as
- Iron (III) maltol
- Code names
- ST10 · ST10-021 · WHO 9974
- Brand names
- Accrufer
- Feraccru
Resolves to
AHPWLYJHTFAWKI-UHFFFAOYSA-KSMILES[Fe+3].CC1=C([O-])C(=O)C=CO1.CC1=C([O-])C(=O)C=CO1.CC1=C([O-])C(=O)C=CO1What you can answer from here — as of August 31, 2026
Which drugs share a target with Ferric maltol, and which of those have an active Phase 3 trial?