CVnCoV

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
CVnCoV
DrugBank Accession Number
DB15844
Background

The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, the company received regulatory approval from German and Belgian Authorities to commence Phase 1 clinical trials of this vaccine (NCT04449276).

Type
Biotech
Groups
Investigational
Synonyms
  • CV07050101
  • SARS-CoV-2 mRNA vaccine
External IDs
  • CVnCoV

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Avoid life-threatening adverse drug events & improve clinical decision support.
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Not Available
CAS number
Not Available

References

General References
  1. Rego GNA, Nucci MP, Alves AH, Oliveira FA, Marti LC, Nucci LP, Mamani JB, Gamarra LF: Current Clinical Trials Protocols and the Global Effort for Immunization against SARS-CoV-2. Vaccines (Basel). 2020 Aug 25;8(3). pii: vaccines8030474. doi: 10.3390/vaccines8030474. [Article]
  2. Speiser DE, Bachmann MF: COVID-19: Mechanisms of Vaccination and Immunity. Vaccines (Basel). 2020 Jul 22;8(3). pii: vaccines8030404. doi: 10.3390/vaccines8030404. [Article]
  3. CureVac & Covid-19 [Link]
  4. Smart Patients [Link]
  5. Regulatory News [Link]
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Active Not RecruitingPreventionCoronavirus Disease 2019 (COVID‑19) / Infections, Coronavirus / Severe Acute Respiratory Syndrome (SARS)2
3Not Yet RecruitingPreventionCoronavirus Disease 2019 (COVID‑19)1
3WithdrawnPreventionCoronavirus Disease 2019 (COVID‑19)1
3WithdrawnPreventionCoronavirus Disease 2019 (COVID‑19) / Infections, Coronavirus / Severe Acute Respiratory Syndrome (SARS)1
2Active Not RecruitingPreventionCoronavirus Disease 2019 (COVID‑19) / Infections, Coronavirus / Severe Acute Respiratory Syndrome (SARS)1
2, 3Active Not RecruitingPreventionCoronavirus Disease 2019 (COVID‑19)1
1Active Not RecruitingPreventionCoronavirus Disease 2019 (COVID‑19) / Infections, Coronavirus / Severe Acute Respiratory Syndrome (SARS)1
1, 2RecruitingPreventionCoronavirus Disease 2019 (COVID‑19)1
Not AvailableActive Not RecruitingNot AvailableCoronavirus Disease 2019 (COVID‑19)1
Not AvailableNot Yet RecruitingPreventionCoronavirus Disease 2019 (COVID‑19) / SARS-CoV-2 Acute Respiratory Disease1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on September 17, 2020 18:37 / Updated on September 18, 2020 08:47