Praliciguat

DB16300InvestigationalSmall molecule

Praliciguat is under investigation in clinical trial NCT03254485 (A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (Hfpef)).

Formula / weight: C₂₁H₁₄F₈N₆O₂ · 534.37 g/mol (avg)
Code names: IW-1973

Resolves to

Compound

UNIIR1S0H458SACAS1628730-49-3ChEMBLCHEMBL4297214ChEBI142431

Structure

InChIKeyCYSJNTQNMDWAJV-UHFFFAOYSA-NSMILESOC(CNC1=NC(=NC=C1F)C1=NN(CC2=C(F)C=CC=C2)C(=C1)C1=NOC=C1)(C(F)(F)F)C(F)(F)F

Targets

Q02153GUCY1B1Q02108GUCY1A1

What you can answer from here — as of April 23, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

7Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Praliciguat, and which of those have an active Phase 3 trial?

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