OM85

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
OM85
DrugBank Accession Number
DB16533
Background

OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.

Type
Biotech
Groups
Investigational
Synonyms
  • Broncho-Vaxom
  • OM 85 BV
  • OM-85
  • OM-85 BV
External IDs
  • OM85

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action

OM85 acts on Trif and MyDD8, and is a NLRP3 activator.

Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
Not Available
CAS number
Not Available

References

General References
  1. Dang AT, Pasquali C, Ludigs K, Guarda G: OM-85 is an immunomodulator of interferon-beta production and inflammasome activity. Sci Rep. 2017 Mar 6;7:43844. doi: 10.1038/srep43844. [Article]
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedPreventionAsthma1
4CompletedPreventionBronchiectasis With Acute Exacerbation1
4RecruitingTreatmentRespiratory Tract Infections (RTI) / Wheezing Lower Respiratory Illness1
4Unknown StatusPreventionAdenoid Hyperplasia / Adenoids Hypertrophy / Preschool Children / Respiratory Tract Infections (RTI)1
3CompletedPreventionAtopic Dermatitis1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at February 01, 2021 19:18 / Updated at February 13, 2021 10:54