OM85

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
OM85
Accession Number
DB16533
Description

OM-85, a bacterial extract, is an immunomodulator of interferon-β production and inflammasome activity.

Type
Biotech
Groups
Investigational
Synonyms
  • Broncho-Vaxom
  • OM 85 BV
  • OM-85
  • OM-85 BV
External IDs
  • OM85

Pharmacology

Pharmacology
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Indication
Not Available
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics
Not Available
Mechanism of action

OM85 acts on Trif and MyDD8, and is a NLRP3 activator.

Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
Medicalerrors
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified

Chemical Identifiers

UNII
Not Available
CAS number
Not Available

References

General References
  1. Dang AT, Pasquali C, Ludigs K, Guarda G: OM-85 is an immunomodulator of interferon-beta production and inflammasome activity. Sci Rep. 2017 Mar 6;7:43844. doi: 10.1038/srep43844. [PubMed:28262817]
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedPreventionAsthma1
4CompletedPreventionBronchiectasis With Acute Exacerbation1
4Unknown StatusPreventionAdenoid Hyperplasia / Adenoid Hypertrophy / Preschool Children / Respiratory Tract Infections (RTI)1
3Active Not RecruitingPreventionCoronavirus Disease 2019 (COVID‑19) / Respiratory Viral Infections1
3CompletedPreventionAtopic Dermatitis (AD)1
2Active Not RecruitingPreventionAsthma / Wheezing1
2RecruitingTreatmentAsthma1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on February 01, 2021 19:18 / Updated on February 13, 2021 10:54