KW-2450

DB16637InvestigationalSmall molecule

KW-2450: Overview.

Mechanism: Pharmacologically active on Insulin receptor and Insulin-like growth factor 1 receptor
Curator reviewed
Formula / weight: C₂₈H₂₉N₅O₃S · 515.63 g/mol (avg)
Code names: KW-2450 free base

Resolves to

Compound

Structure

InChIKeyHHCSNTXVZDWIGT-CMDGGOBGSA-NSMILESCC1=C(SC=C1)C(=O)NC1=CC(CN2CCN(CC2)C(=O)CO)=CC=C1\C=C\C1=NNC2=CC=CC=C12

Targets

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with KW-2450, and which of those have an active Phase 3 trial?

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