Insulin-like growth factor 1 receptor

BE0000858ProteinHumansIGF1R

Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). It is acted on by 44 drugs in DrugBank.

Gene name
IGF1R
UniProtKB entry
P08069Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,367 residues · 154,792 Da
Also known as
2.7.10.1 · IGF-I receptor · Insulin-like growth factor I receptor

Resolves to

Protein
UniProtP08069UniProt nameIGF1R_HUMAN
Gene
HGNCHGNC:5465NCBI Gene3480GenBank804990GeneCardsIGF1R
Pharmacology
IUPHAR/GtoPdb1801KEGGhsa:3480
Structure
PDB1IGRPDB1JQHPDB1K3A
Drugs

What you can answer from here — as of September 07, 2019

44DrugsApproved to experimental, with action, bond type and pharmacological action
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26Clinical trialsTrials of drugs acting on it, by phase and status
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18GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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150+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Insulin-like growth factor 1 receptor, how selective are they, and which programs against it are still in active trials?

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