Insulin receptor

BE0000033ProteinHumansINSR

Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. It is acted on by 35 drugs in DrugBank.

Gene name
INSR
UniProtKB entry
P06213Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,382 residues · 156,331 Da
Also known as
2.7.10.1 · IR

Resolves to

Protein
UniProtP06213UniProt nameINSR_HUMAN
Gene
HGNCHGNC:6091NCBI Gene3643GenBank307070GeneCardsINSR
Pharmacology
IUPHAR/GtoPdb1800KEGGhsa:3643
Structure
PDB1GAGPDB1I44PDB1IR3
Drugs

What you can answer from here — as of September 07, 2019

35DrugsApproved to experimental, with action, bond type and pharmacological action
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5Clinical trialsTrials of drugs acting on it, by phase and status
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30GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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208+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Insulin receptor, how selective are they, and which programs against it are still in active trials?

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