This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- ODM-203
- DrugBank Accession Number
- DB16843
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
Structure for ODM-203 (DB16843)
- Weight
- Average: 505.54
Monoisotopic: 505.138402436 - Chemical Formula
- C26H21F2N5O2S
- Synonyms
- Not Available
- External IDs
- ODM203
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Y7HJ4D4CRT
- CAS number
- 1430723-35-5
- InChI Key
- ZJFCBQXPTQSTCZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C26H21F2N5O2S/c1-32-14-18(13-30-32)16-2-7-26-25(10-16)29-15-33(26)21-9-17(23-6-3-19(27)11-24(23)28)8-20(12-21)31-36(34,35)22-4-5-22/h2-3,6-15,22,31H,4-5H2,1H3
- IUPAC Name
- N-{2',4'-difluoro-5-[5-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-1-yl]-[1,1'-biphenyl]-3-yl}cyclopropanesulfonamide
- SMILES
- CN1C=C(C=N1)C1=CC2=C(C=C1)N(C=N2)C1=CC(=CC(NS(=O)(=O)C2CC2)=C1)C1=C(F)C=C(F)C=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 61733207
- BindingDB
- 247327
- ChEMBL
- CHEMBL3964954
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 1 Completed Other Healthy Volunteers (HV) 1 1 Completed Other Solid Tumors 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0228 mg/mL ALOGPS logP 4.48 ALOGPS logP 4.29 Chemaxon logS -4.4 ALOGPS pKa (Strongest Acidic) 9.72 Chemaxon pKa (Strongest Basic) 4.76 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 81.81 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 153.71 m3·mol-1 Chemaxon Polarizability 51.98 Å3 Chemaxon Number of Rings 6 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at July 18, 2022 20:54 / Updated at December 01, 2022 11:31