NAV

NB-124 sulfate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
NB-124 sulfate
DrugBank Accession Number
DB16951
Background

Not Available

Type
Small Molecule
Groups
Investigational
Structure
Similar Structures
Weight
Average: 580.6
Monoisotopic: 580.226173158
Chemical Formula
C19H40N4O14S
Synonyms
  • 6'-(r)-methyl-5-o-(5-amino-5,6-dideoxy-a-l-talofuranosyl)- paromamine sulfate
  • 6'-(r)-methyl-5-o-(5-amino-5,6-dideoxy-alpha-l-talofuranosyl)-paromamine sulfate
  • D-streptamine, o-5-amino-5,6-dideoxy-.beta.-d-allofuranosyl-(1->5)-o-(2-amino-2,7-dideoxy-d-glycero-.alpha.-d-gluco-heptopyranosyl-(1->4))-2-deoxy-, sulfate
  • Elx-02 sulfate
  • Exaluren disulfate
  • Exaluren sulfate

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
DZ671709NT
CAS number
1375073-96-3
InChI Key
BOIAUNVCOPGNOT-STOTURBNSA-N
InChI
InChI=1S/C19H38N4O10.H2O4S/c1-4(20)14-12(28)13(29)19(30-14)33-17-9(25)6(21)3-7(22)16(17)32-18-8(23)10(26)11(27)15(31-18)5(2)24;1-5(2,3)4/h4-19,24-29H,3,20-23H2,1-2H3;(H2,1,2,3,4)/t4-,5+,6+,7-,8+,9-,10+,11-,12-,13+,14+,15+,16+,17+,18+,19-;/m0./s1
IUPAC Name
(2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-5-[(1S)-1-aminoethyl]-3,4-dihydroxyoxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-[(1R)-1-hydroxyethyl]oxane-3,4-diol; sulfuric acid
SMILES
OS(O)(=O)=O.[H][C@@]1(O[C@@H](O[C@]2([H])[C@@H](O)[C@H](N)C[C@H](N)[C@H]2O[C@@]2([H])O[C@]([H])([C@@H](C)O)[C@@H](O)[C@H](O)[C@H]2N)[C@H](O)[C@@H]1O)[C@H](C)N

References

General References
Not Available
ChemSpider
28648305
ChEMBL
CHEMBL2206194

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility38.4 mg/mLALOGPS
logP-2.5ALOGPS
logP-5.6Chemaxon
logS-1.1ALOGPS
pKa (Strongest Acidic)12.19Chemaxon
pKa (Strongest Basic)9.71Chemaxon
Physiological Charge4Chemaxon
Hydrogen Acceptor Count14Chemaxon
Hydrogen Donor Count10Chemaxon
Polar Surface Area262.38 Å2Chemaxon
Rotatable Bond Count6Chemaxon
Refractivity109.01 m3·mol-1Chemaxon
Polarizability48.34 Å3Chemaxon
Number of Rings3Chemaxon
Bioavailability0Chemaxon
Rule of FiveNoChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleYesChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at September 14, 2022 19:09 / Updated at April 20, 2023 07:02