IT-139
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Identification
- Generic Name
- IT-139
- DrugBank Accession Number
- DB17145
- Background
Not Available
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 502.14
Monoisotopic: 500.875172 - Chemical Formula
- C14H12Cl4N4NaRu
- Synonyms
- Ruthenate(1-), tetrachlorobis(1h-indazole-.kappa.n2)-, sodium (1:1), (oc-6-11)-
- Sodium hydride; tetrachloro-bis(1h-indazol-2-yl)ruthenium
- Sodium Trans-[Tetrachlorobis(1H-Indazole)Ruthenate(iii)]
- External IDs
- IT-139
- KP-1339
- NKP-1339
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 7OSJ9KS483
- CAS number
- 197723-00-5
- InChI Key
- YGDDGJPSWMFECS-UHFFFAOYSA-J
- InChI
- InChI=1S/2C7H6N2.4ClH.Na.Ru/c2*1-2-4-7-6(3-1)5-8-9-7;;;;;;/h2*1-5H,(H,8,9);4*1H;;/q;;;;;;+1;+4/p-4
- IUPAC Name
- sodium tetrachlorobis(1H-2lambda4-indazol-2-yl)ruthenium
- SMILES
- [Na+].Cl[Ru](Cl)(Cl)(Cl)([N]1=CC2=CC=CC=C2N1)[N]1=CC2=CC=CC=C2N1
References
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 1 Completed Treatment Solid Tumors 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.00293 mg/mL ALOGPS logP 4.61 ALOGPS logP 6.15 Chemaxon logS -5.2 ALOGPS pKa (Strongest Acidic) 15.79 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 41.44 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 137.02 m3·mol-1 Chemaxon Polarizability 37.85 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at November 21, 2022 16:03 / Updated at December 01, 2022 11:35