Senaparib

DB17163InvestigationalSmall molecule

Senaparib: Overview.

Mechanism: Pharmacologically active on Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymerase 2
Curator reviewed
Formula / weight: C₂₄H₂₀F₂N₆O₃ · 478.46 g/mol (avg)
Also known as: 2,4(1h,3h)-quinazolinedione, 5-fluoro-1-((4-fluoro-3-((4-(2-pyrimidinyl)-1-piperazinyl)carbonyl)phenyl)methyl)- · 5-fluoro-1-((4-fluoro-3-((4-(2-pyrimidinyl)-1-piperazinyl)carbonyl)phenyl)methyl)-2,4(1h,3h)-quinazolinedione
Code names: IMP-4297

Resolves to

Compound

Structure

InChIKeyVBTUJTGLLREMNW-UHFFFAOYSA-NSMILESFC1=C(C=C(CN2C(=O)NC(=O)C3=C(F)C=CC=C23)C=C1)C(=O)N1CCN(CC1)C1=NC=CC=N1

Targets

What you can answer from here — as of September 16, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

12Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Senaparib, and which of those have an active Phase 3 trial?

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